first trimester Flashcards
What is the smallest fetal pole that a competent ultrasonologist would confidently diagnose as nonviable due to absence of cardiac activity?
a. 7 mm
b. 9 mm
c. 13mm
d. 17mm
e. 21mm
7mm
What is the smallest gestational sac size that a competent ultrasonologist would confidently diagnose as a blighted ovum because of lack of fetal pole?
a. 11mm
b. 15mm
c. 19mm
d. 23mm
e. 27mm
25mm
A woman presents with abdominal pain at 6 weeks amenorrhoea, BHCG is 6000, US empty uterus. O/E tender adnexae. Best next step:
- serial BCHG
- rpt US in 1 week
- laparoscopy
- laparotomy
- laparoscopy
Presents at 7 weeks after TOP 1 week ago. Still symptoms of pregnancy. O/E 7/40 size uterus, urinary BHCG positive. Op notes from TOP report minimal tissue, histopath: decidual tissue only. Next step:
- TV U/S
- Expoloratory laparotomy
- Reassurance
- TV USS
What is the concern about a pregnancy after failed morning after contraception?
- multiple pregnancy
- abnormal fetus
- increased risk of ectopic pregnancy
- increased risk of miscarriage
- higher risk of premature labour
- increased risk of ectopic pregnancy
A 21 yo woman has an US at 7/40 for lower abdominal pain. A viable 7/40 pregnancy is seen, and an 8cm single locular cystic structure is noted in the right adnexa. What management option do you choose?
- Reassure and review regularly
- RSO through a Pfannensteil incision
- RSO through a midline incision
- US guided drainage of the cyst
- Rescan in 6/52
- Rescan in 6/52
The most common presenting symptom for molar pregnancy is:
- abnormal bleeding
- hyperemesis
- fundus larger than dates
- thryotoxicosis
- pre-eclampsia
- abnormal bleeding
Concerning partial moles, which statement is incorrect?
- the fetus may be alive
- most are triploidic
- more often progress to choriocarcinoma than complete moles
- pre-eclampsia is more common with partial moles
- more often progress to choriocarcinoma than complete moles
Regarding hydatidiform mole, which statement is correct:
- <3 % progress to chroiocarcinoma
- choriocarcinoma can be associated with thyrotoxicosis
- commonest karyotype is 45 XO
- association between prognosis and rhesus blood group
- less common in older women
- choriocarcinoma can be associated with thyrotoxicosis
- <3 % progress to chroiocarcinoma
“however persistence or change into malignant disease requiring chemotherapy occurs in 0.5 – 4 per cent of partial moles” - RANZCOG
Concerning partial moles, all true except:
- fetus may be alive
- mostly triploidy
- same follow up as complete moles – different now, follow up if negative within 8 weeks then 3/12
- more often go on to choriocarcinoma than complete moles
- preeclampsia occurs most commonly with partial moles
- more often go on to choriocarcinoma than complete moles
Least valuable predictor of missed abortion
- 5mm sac with no heart beat
- 15 mm sac with no fetal pole
- 20 mm sac and no fetal heart beat
- 5mm sac with no heart beat
Spontaneous ab, correct option:
- increased in women > 40
- DES associated with many pregnancy problems but no spont ab
- Most common chromosomal abnormality is triploidy
- Genetic abnormality in aborted fetuses are similar to those occurring in term fetuses
- increased in women > 40
A woman with 4 previous 1st trimester miscarriages has been fully investigated, no cause found. Management for the next pregnancy is:
- progesterone supplement empirically, or test serum progesterone
- aspirin and heparin
- serial BHCG
- US at 6/40
- US at 6/40
In first trimester, a PG presents with N & V, tachycardia. TFT show slight increase in free T4, decrease in TSH, and normal RT3. This is associated with:
- normal
- hyperemesis gravidarum
- Graves disease
- Hashimoto’s thyroiditis
- Non-toxic goitre
- hyperemesis gravidarum
A woman has three first miscarriages and presented to you at 6 weeks gestation. What is the next most appropriate step?
- perform an U/S
- serum bHCG
- reassurance
- lupus screen
- commence on progesterone
- perform an U/S
Patient 16 days after expected period. PV spotting in casualty. BHCG is 140,000. Most likely diagnosis?
- multiple pregnancy
- intrauterine pregnancy
- missed ab
- ectopic pregnancy
- intrauterine pregnancy and dysgerminoma of the ovary
- intrauterine pregnancy
After which procedure is the decay rate of BHCG the fastest?
- vacuum curette for termination of pregnancy
- vacuum curette for spontaneous abortion
- resection of ectopic pregnancy
- linear salpingotomy for ectopic pregnancy
- BHCG decays at the same rate for all procedures
- BHCG decays at the same rate for all procedures
Which investigation delivers the greatest dose of radiation to an 8 weeks fetus?
- IVP
- CXR
- Cholecystogram
- Barium enema
- Lumbar spine series
- Barium enema
In a woman who conceives with an IUD insitu, all of the following are associated EXCEPT:
- miscarriage
- prematurity
- low birth weight
- fetal abnormalities
- chorioamnionitis
- fetal abnormalities
Suction curettage for missed abortion at 10/40. What size suction catheter should you use?
- 6
- 8
- 10
- 12
- 14
- 10
The most likely place of damage if haemorrhage and suction D&C?
- anterior laceration of corpus
- posterior laceration of corpus
- lateral laceration of corpus
- cervical laceration
- cervical laceration
(vs lateral laceration of corpus- uterines)
At 7 weeks gestation, which of the following findings is most likely to be consistent with a tubal ectopic pregnancy?
- abdo US empty uterus + BHCG <600
- abdo US empty uterus + BHCG <1000
- abdo US empty uterus + BHCG >7000
- abdo pain and negative culdocentesis
- abdo US empty uterus + BHCG >7000
A woman had a termination of pregnancy at 8/40 gestation at a local clinic under LA. The cervix was difficult to dilate and the uterus appeared to be perforated during this dilation. There was no bleeding or pain. A TVS was performed and showed a viable 8/40 fetus with an intact sac. What is the most appropriate management?
- continue with the termination
- transfer to hospital and continue termination under GA
- insert a cervagem vaginally and wait 4 hrs then attempt the suction termination
- perform a laparotomy and repair the defect, continue with suction termination with hysterotomy and removal of POC if necessary
- stop the procedure and wait 1-2 weeks then reconsider
- stop the procedure and wait 1-2 weeks then reconsider
3 recurrent abortions, no cause found after investigation. Now 6/40 in next pregnancy, next step:
- aspirin
- progesterone
- quantitative HCG
- transvaginal US
- TV USS
Regarding ectopics
- Continuing US and BHCG delays intervention and leads to greater risk of rupture
- Recurrence risk about 10%
- Better chance of subsequent live birth with salpingostomy vs salpingectomy
- Better chance of subsequent live birth with salpingostomy vs salpingectomy
recurrence risk 15%
RCOG : The three-year cumulative pregnancy rate was 62% after salpingotomy and 38% after salpingectomy
37 yo has just had 4th 1st trimester miscarriage within her only marriage and no living children. Most likely cause
- idiopathic
- lupus
- chromosomal
- cervical incompetence
- idiopathic
What is of proven value as treatment for recurrent 2nd trimester miscarriages associated with uterine contractions?
- erthromycin
- transfusing wife with husbands WBC
- Strassmann operations
- McDonald cerclage
- McDonald cerclage
Recurrent abortion, no cause found. What do you do at 6-7/40 in next pregnancy?
- pelvic US
- cervical suture
- BHCG
- Progesterone injections
- pelvic US
A lady 12 weeks pregnant with a bicornuate uterus presents to A&E with pain and bleeding. US shows an empty uterus and 8 cm adnexal mass. Obs BP 90/60, PR 110:
- get A&E to organise laparoscopy with probable salpingostomy
- get A&E to organise laparoscopy with probable laparotomy
- do nothing until you arrive in 30 mins
- have a culdotomy tray ready for you
- get A&E to organise laparoscopy with probable laparotomy
At 12 weeks gestation the corpus luteum is removed for bleeding, the most appropriate pregnancy support with the least fetal risk is:
- duphaston
- depo provera
- norethisterone
- progesterone and oestrogen
- no hormones
- no hormones
Commonest cause of first trimester miscarriage?
- T21
- XO
- T16
- T18
- XXY
- XO
Altogether, the trisomies make up 50% of chromosomal causes, T16 being the most common and always lethal. On its own XO comprises 20% so is probably most common
A woman you have been following with a bicornuate uterus had her LNMP 11/52 ago. A home pregnancy test was positive 2/52 ago. She has presented to ED with severe lower abdominal pain and bleeding O/E HR 110, BP 90/60, lower abdomen rigid and US 6 cm adnexal mass and empty uterus. Mx?
- ask for stat LFT’s plt in preparation for MTX
- ask for a culdocentesis tray to be organised
- have them do nothing until you arrive in < 30 mins
- begin arranging theatre for laparoscopy/likely linear salpingostomy
- begin arranging theatre for laparoscopy probably laparotomy
- begin arranging theatre for laparoscopy probably laparotomy
A 21 yo primigravida at 14 weeks is found to have a BP of 180/110. The BP was noted to be normal at her first visit and prior to pregnancy. Of the possible diagnoses, the most lethal is?
- PIH
- Acute glomerulonephritis
- Essential HT
- Hydatidiform mole
- Phaeochromocytoma
- Phaeochromocytoma
In a woman who is 8 weeks pregnant with an IUD in situ the correct management is?
- immediate removal of the IUD
- advise termination of pregnancy
- remove the IUD only if there is evidence of infection
- if the strings are visible cut them as high up in the cervical canal as possible
- immediate laparoscopy to exclude ectopic pregnancy
- immediate removal of the IUD
The most common emotional response after a termination is
- severe depression
- shame
- relief
- anxiety
- psychosis
- relief
27 yo female at 7/40 pregnant with 8 cm unilocular cyst presents with LIF pain. Mx?
- operative laparoscopy
- cystectomy via pfannensteil
- oopherectomy via midline incision and washings
- laparoscopy and aspiration of cyst
- repeat US in 6 weeks
- repeat US in 6 weeks
Ectopic pregnancvy
- increased after legal TOP
- increased on progesterone only pill more than without contraception
- rate is higher with copper IUD’s than plastic ones
- increased with IUD more than normal population
- none of the above
- none of the above
TOP at 6/52. One week later, no bleeding or pain but BHCG remains positive. There is a 6-7 week size uterus. The path showed scanty decidual tissue, no fetal parts. Next ?
- qualitative BHCG
- ultrasound
- repeat curette
- laparotomy
- ultrasound
6/52 pregnant, 3 days of abdo pain and 2 days of PV bleeding. Bilateral adnexal tenderness. US – complex adnexal mass and free fluid in POD. Next?
- culdocentesis
- laparotomy
- quantitative BHCG
- laparoscopy
- laparoscopy
12 weeks pregnant. HCG positive at 6 weeks. No other antenatal care. Feels pregnant. One week history of PCB without cramping. Speculum reveals bright red 3 cm mass on the ectocervix. Which test will give a definite diagnosis?
- real time US
- tissue biopsy
- colposcopy and biopsy
- stain with Lugo’s iodine
- real time US
Risk of ectopic highest with?
- COCP
- Condoms
- No contraception
- POP
- diaphragm
- no contraception
Threatened ab at 6 weeks shows cardiac activity and appropriate for dates. Risk of ab?
- <10%
- 50%
- 25%
- 90%
- <10%
Woman at 6/52 amenorrhoea with PV bleeding and lower abdo pain. HCG 3000 and US empty uterus. Options?
- do nothing
- serial HCG
- laparoscopy
- laparoscopy
Pregnant lady in first trimester with the following GTT. Fasting BSL 6.8, 2 hrs post 100gm load 12.6. Mx?
- admit for stabilisation
- commence on oral hypoglycaemic agent
- commence on insulin as an outpatient
- repeat the test in the second trimester
- counsel on dietary measures
- commence on insulin as an outpatient
vs admit for stabilisation