First/Second line HTN

Question 1

Trial that led to goal of less than 130/80?

Answer 1

SPRINT

Question 2

Trial that led demonstrated benazepril better with DHP CCB?

Answer 2

ACCOMPLISH

Question 3

Secondary stroke (Hx of stroke or TIA) 1st line?

Answer 3

thiazide or ACEi/ARB or combo with both

second line: DHP CCB

Question 4

HFrEF 1st line?

Answer 4

ACE/ARB/ARNI AND BB

metoprolol succinate, bisoprolol, carvedilol

Question 5

HFrEF 2nd lines?

Answer 5

MRA
hydralazine + isosorbide dinitrate (African Americans)
loop diuretic

Question 6

HFpEF with fluid overload first line?

Answer 6

diuretics

Question 7

HFpEF w/o fluid overload first line?

Answer 7

ACEi/ARB and/or BB

Question 8

HFpEF w/o fluid overload second line?

Answer 8

DHP CCB

Question 9

SIHD first line?

Answer 9

ACEi/ARB AND BB

Question 10

SIHD second line?

Answer 10

DHP CCB
thiazide
MRA

Question 11

Diabetes without albuminuria first line?

Answer 11

thiazide, DHP CCB, or ACEi/ARB

Question 12

Diabetes with albuminuria first line?

Answer 12

ACEi/ARB

Question 13

DM with albuminuria second line?

Answer 13

DHP CCB and thiazide

Question 14

CKD stage 1 or 2 without albuminuria first line?

Answer 14

thiazide, DHP CCB, or ACEi/ARB

Question 15

CKD stage 1 or 2 with albuminuria or CKD stage 3 or higher first line?

Answer 15

ACEi/ARB

second line:
DHP CCB and thiazide

Question 16

What trial found ACEi/ARB combo gave no benefit?

Answer 16

ONTARGET