First Lecture Flashcards

1
Q

What are the 6 levels of organization?

A

Chemical, Cellular, Tissue, Organs, Organ System, and Organism

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2
Q

What elements are found at the chemical level?

A

C, O, H, N, P, S

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3
Q

What is the difference between living and nonliving things?

A

Energy expended to arrange their molecules in a certain way.

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4
Q

What are the 4 basic components or structures in a cell?

A

Plasma membrane, cytosol, DNA, and ribsomomes.

Also, cells essentially interact with the environment and maintain a level of organization of the chemicals.

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5
Q

What makes an organ?

A

-Two or more tissues organized together

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6
Q

What is an organ system?

A

Two or more organs working together

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7
Q

What makes an organism?

A

-An entire being.

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8
Q

What makes a living thing?

A

-Living things are composed of a single cell or a group of cells, at least physical and chemical machines, respond to short-term changes in their environment, grow and reproduce, adapt to long-term changes in their environment via natural selection

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9
Q

What is the boundary organ concept?

A

Some organ systems are on the boundary (fluid side, internal environment, the fluid that surrounds your cells) and the external environment (that faces the external environment). Boundary organs are on the interface. They are the gatekeepers. The function of boundary organs is very important for homeostasis. Wastes and excesses and water balance are affected if they do not perform well, and if they are impaired so is homeostasis.
Nutrients control: salt and water. One of the most important things that your integumentary system does is to keep water in. How about waste? Not a HUGE function, but you do lose toxins and salts through sweat! Urea is a nitrogen-containing waste. Before dialysis, they would put you in a tub full of salts to sweat out toxins.
-All boundary organs are involved in energy exchange and essentially makes sure everything is in balance for with the cardiovascular, skeletal, muscle, and nervous system.
-Kidneys as a boundary organ: filter wastes and nutrients from the blood. Rely on circulation to perform their function but also to provide for the nonboundary organ cell.

The Boundary Organ Tissue that is responsible for making the changes to the blood, then the blood mixes up those changes. Boundary Organ is one that DIRECTLY exchanges with outside environment.

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10
Q

Does the boundary organ system help maintain tolerable conditions inside or outside the cell?

A

Outside of Cells!

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11
Q

What does the capillary epithelium do?

A
  • Capillaries are permeable. This is helpful because we can’t have a capillary to every cell.
  • They are charged with regulating the amount of tissue between blood and interstitial fluid.
  • Small.
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12
Q

ECF?

A
  • Sodium: same size bubble, equal concentrations.
  • Pores allow sodium to move freely, and as it moves you reach equilibrium. Potassium as well. Not as much potassium as sodium
  • Antibodies, clotting factors, hormones, once in blood stays in blood unless moved.
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13
Q

ICF?

A

ICF calcium is sequestered in membranous organelles. Stores things. SER. Golgi apparatus: UPS packages and labels. Smooth ER stores lots of calcium. Maintains concentration gradient for calcium to be favored to move in when needed.
Cells spend most of their life spending their DNA to make proteins. Cell membrane does NOT allow it to diffuse out. Only way out is by active transport.

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14
Q

Why are proteins soluble in cytosol?

A

They have a charge. Similarly phosphates, phosphorus and oxygen compounds. They contribute to a negative charge inside of cells.

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15
Q

Is there a high or low concentration of Na+ outside of the cell?

A

High

How many sodium are pumped out? –> 3

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16
Q

Is there high or low concentration of K+ outside of the cell?

A

Low

how many potassium are pumped in? 2

17
Q

How does the sodium/potassium pump work?

A

Pumps sodium outside of the cell and pumps potassium inside of the cell.
-So there is very little sodium inside of the cell while there is a lot of potassium inside of the cell

18
Q

Where do you find the most calcium?

A
  • Inside of membranous organelles
  • Membrane bound organelles= Mitochondria, Nucleus, Endoplasmic Reticulum, Golgi Apparatus, Lysosomes, Peroxisomes, Vesicles.
19
Q

Are the compartments (ICF, ECF) best described as hypertonic or isotonic to each other?

A

Isotonic

20
Q

How does the cell maintain the concentrations of ions as shown on this table?

A

Concentration and electrochemical gradients.

21
Q

Is the inside or outside of the cell more negative? and why?

A

Inside of a cell is more negative
-The sodium/potassium pump is pumping 3 positively charged sodium out, 2 positively charged potassium in, while there are increased amounts of phosphate and proteins on the inside of the cell contributing to an overall negative charge on the inside of the cell.

22
Q

How is homeostasis controlled?

A
  • Boundary organs work to maintain the ECF.
  • Change occurs and needs to be detected via receptors in the body. Change is detected by chemical and pressure receptors in the ECF. Receptors only detect the rate and direction of change.
  • Most receptors are located in the nervous and endocrine system. Why? –> signals like chemical and nerves.
  • Homeostasis implies static but in reality, it fluctuates.
23
Q

What are the three components of the feedback loop?

A
  1. Receptor= monitors a controlled condition
  2. Control Center= determines next action
  3. Effector = receives directions from the control center and produces a response that changes the controlled condition
24
Q

Describe Negative Feedback in the control of Blood Pressure

A
  • Pressure receptors in walls of certain arteries detect an increase in BP
  • Blood Pressure = hydrostatic pressure; the force of blood on walls of vessels
  • Brain receives and integrates input
  • Brain signals heart and blood vessels
  • Heart rate slows and vessels dilate (increase in diameter)

-BP remains normal

25
Q

Describe Postive Feedback during Childbirth

Can you name two other examples of a positive feedback mechanism?

A
  • Stretch receptors in walls of uterus send signals to the brain
  • Brain causes release of hormone (oxytocin) into bloodstream
  • Uterine smooth muscle contracts more forcefully
  • More stretch, more hormone, more contraction etc.
  • Cycle ends with birth of the baby & decrease in stretch

-Two other mechanims= blood clotting and muscle contraction

26
Q

Describe the Feedforward mechanism indigestion

A
  • Chemoreceptors in nose and mouth send signals to the brain
  • Brain sends nervous signals to stomach
  • Stomach smooth muscle and glands activated before food arrives!
  • Stomach also releases hormone Gastrin, to recruit a positive feedback mechanism!
  • This positive feedback mechanism is eventually stopped by feedback mechanisms that are similar to that of a metabolic pathway.