First Aid Flashcards
What is the formula for Alveolar Ventilation (VA)?
VA = (VT - VD) x RR
Tidal volume - Dead space, x RR (12-20 breaths/min)
Pathology- hyperplasia of mucus-secreting glands bronchi–> Reid index (thickness of gland layer/total thickness of bronchial wall) >50%.
Productive cough for 3 months per year for at least 2 years. Findings: wheezing, crackles, cyanosis,
Chronic bronchitis
Desquamated epithelium casts in sputum, Charcot-Leyden Crystals… What is the associated disease?
Curschmann’s spirals (bronchial asthma)
Charcot-Laden crystals are double pointed hexagonal crystals that are formed when eosinophils in sputum breakdown.
What pathology is at hand: Opacities seen on X-ray on both sides of the carina. bilateral hilar lymphadenopathy, uveitis
Sarcoidosis
What is the formula for the calculation of physiologic dead space?
Vd = Vt x (PaCO2 - PECO2/PaCO2)
Where Vt is the Tidal Volume (~500mL)
What pathology is at hand: Vasculitis and glomerulonephritis
Goodpasture’s, Wegener’s
What pathology is at hand: Anti-glomerular basement membrane antibodies
Goodpasture’s
What pathology is at hand: Honeycomb lung on x-ray
Interstitial fibrosis
What pathology is at hand: Tennis-racket shaped cytoplasmic organelles
Birbeck granules
What pathology is at hand: Iron containing nodules in the alveolar septum. What are they and what is the associated pathology?
Ferruginous bodies - Asbestos related disease
Idiopathic pulmonary hypertension is associated with what gene mutation?
BMPR2 gene (inhibits vascular smooth muscle proliferation).
MCC of pneumonia in immunocompromised patients?
Pneumocystis jiroveci
MCC of atypical/walking pneumonia?
Mycoplasma pneumonia
Causative agent for pneumonia in alcoholics?
Klebsiella pneumoniae
Pneumonia associated with bird handlers?
Chlamydia psittaci