Fire Facts Flashcards
What is the hallmark sign for COPD? (Ratios)
Decreased FEV1 to FVC ratio
What is the hallmark sign of a Restrictive Lung disease?
A decrease in lung capacity, and a normal FEV1/FVC ratio
How does the emphysema from smoking different from alpha-1-anti trypsin deficiency?
The emphysema from smoking is typically Centricacinar (centribulbar) while emphysema from alpha-1-antiprypsin deficiency is Panacinar
What are the causes of a trasudative pleural effusion?
- CHF
- Cirrhosis
- Nephrotic Syndrome
- Pulmonary embolus
- Fluid overload
What are the causes of exudative pleural effusions?
- Pneumonia
- Infection
- TB
- Cancer
- Uremia
- Connective tissue disease
What is the triad in Kartagener Syndrome? What is the defect?
Triad:
Situs Inversus
Bronchiectasis
Recurrent sinusitis
Dynein arm defect—> immotile cilia
What lung tumors arise centrally in the lung and are linked to smoking? Which tumors tend to arise peripherally in the lung?
Central - squamous cell, small cell: smoking central S sounds
Peripherally - Adenocarcinoma, Large Cell carcinoma
How is alveolar 02 calculated?
Alveolar gas equation
PAO2 = 150mmHg - (PaCO2/0.8)
What is the A-a gradient?
PAO2 - PaO2
Normally around 10 to 15… (a big change is bad news, no oxygenation)
What is being described: Inadequate PaO2 due to the following: -High Altitude -Hypoventilation -Pulmonary fibrosis - R to L cardiac shunt -V/Q mismatch
Hypoxemia
What is being described: Inadequate O2 delivery to organs/tissue: -Anemia -CO poisoning -Low cardiac output -Hypoxemia
Hypoxia
What pathology is being described:
Inadequate perfusion
-Obstruction of arterial flow (MI or stroke)
-Reduced venous drainage
Ischemia
What are the sinus cavities associated with sinusitis?
Ethmoid, frontal, maxillary, and sphenoid sinuses
What is Virchow’s triad for a DVT?
- Stasis (post op, long drive/flight)
- Hypercoagulability (OCPs, defect in coagulation proteins-factor V, pregnancy)
- Endothelial damage (exposed collagen - vessel trauma, fractures, bacterial infections, foreign bodies)
What are the associated Obstructive Lung Diseases?
- Chronic bronchitis
- Emphysema
- Asthma
- Bronchiectasis