Fine tuning for Exam 2 Flashcards
1
Q
Gastrin is made by what cells and what’s its function? What inhibits it?
A
- G cells of antrum, duodenum, and jejunum
- Stimulates gastric acid
- Inhibited by somatostatin
2
Q
CCK is made from what cells? What inhibits it?
A
- I cells of duodenum, jejunum, and ileum
- Somatostatin
3
Q
Secretin is secreted by what cells? What’s its action and what is it inhibited by?
A
- S cells of duodenum, jejunum, and ileum
- decreases gastric acid and increases HCO3-
- Inhibited by somatostatin
4
Q
Ghrelin is secreted by what cells? What’s its action and what is it inhibited by?
A
- X cells of the stomach
- Food intake/hunger, increase in gastric acid
5
Q
Motilin is secreted by what cells?
What’s its action and what inhibits it?
A
- increase in migrating motor complex
- increase in gastric and intestinal motility
6
Q
Incretins (GIP and GLP-1)
-stimulate insulin increase
A
GIP (k cells)
- secretion is stimulated by FA, AA, and carbs
- stimulates glucagon secretion
GLP-1 (L cells)
- only stimulated by carbs
- decreases glucagon release
7
Q
Paracrine control of GIT
A
1) Somatostatin (d cell)
- potent inhibitor
2) Serotonin (EC cell)
- excitatory
3) Histamine (ECL, mast cells)
- specific receptor (excitatory)
