Finding Dangerous Mucosa

Question 1

localized

Answer 1

29%
confined to primary site

Question 2

regional

Answer 2

48%
spread to regional lymph nodes

Question 3

distant

Answer 3

19%
cancer has metastasized

Question 4

unknown

Answer 4

4%
unstaged

Question 5

CLASSIC PATIENT PROFILE OF
ORAL SQUAMOUS CELL CARCINOMA
(2)

Answer 5

 Male, over 50 years, smoker, drinker
 This profile is changing with the emergence of a subset of
OPSCC caused by sexual transmission of high-risk types
of HPV

Question 6

CLINICAL PRESENTATION OF POTENTIALLY
PRE-MALIGNANT AND MALIGNANT LESIONS
(6)

Answer 6

 Leukoplakia
 Erythroplakia
 Erythroleukoplakia
 Chronic ulceration
 Exophytic
 Endophytic

Question 7

 Exophytic
(4)

Answer 7

 Mass-forming
 Fungating
 Papillary
 Verruciform

Question 8

 Endophytic
(3)

Answer 8

 Invasive
 Burrowing
 Ulcerated

Question 9

EVIDENCE BASED FINDINGS:
 “Overall, there is ”

Answer 9

insufficient evidence to support or refute the use of visually-based examination adjuncts.

Question 10

TRANSEPITHELIAL BRUSH TEST
(3)

Answer 10

 Oralscan Laboratories, Suffern, NY
 OralCDx test kit
 Computer assisted oral brush biopsy analysis

Question 11

ORALCDX BRUSH TEST REPORT
 Negative -
* Positive –
 Atypical -

Answer 11

no cellular abnormalities
epithelial dysplasia or
carcinoma
- Scalpel biopsy indicated
abnormal epithelial changes
- Scalpel biopsy indicated

Question 12

ORALCDX TRANSEPITHELIAL BRUSH TEST
 Drore Eisen, DDS, MD, Medical Director Oralscan Laboratories:
 “The brush test is used to test
 “These are lesions that dentists do not find sufficiently suspicious to

Answer 12

benign-appearing lesions that have been either watched
or ignored in the past.”

warrant referral for
scalpel biopsy, not those distinguished by signs and symptoms of malignancy, clear
indications for scalpel biopsy.”

Question 13

EVIDENCE BASED FINDINGS:
* Given the lack of data on the effectiveness of adjunctive cancer detection techniques in general dental
practice settings,

Answer 13

clinicians must rely on a thorough oral mucosal examination supported by specialty referral
and /or tissue biopsy for oral premalignant and malignant lesion diagnosis”

Question 14

OMINOUS CLINICAL SIGNS THAT SHOULD PROMPT BIOPSY
(5)

Answer 14

 Intense whiteness
 Redness, ulceration bleeding
 Granular or verruciform surface
 Exophytic growth
 Mass formation, induration