Finals Flashcards
Block 1
In which layer are the keratohyaline granules found? A. Stratum corneum B. Stratum lucidum C. Stratum granulosum D. Stratum spinosum
C. Stratum granulosum D. Stratum spinosum Keratohyalin granules primarily exist within the stratum granulosum, with some present in the stratum spinosum.
10/M brought in by his parents for hair loss. You note that part of his eyelashes are missing too. During the clinic visit he unconsciously and constantly pulls at his hair. The most likely diagnosis is? A. Male pattern baldness B. Tinea capitis C. Telogen effluvium D. Trichotillomania
D. Trichotillomania Male pattern baldness - loss of hair on the scalp in men. It happens as hormone levels change over a man’s lifetime Tinea capitis - Caused by superficial fungal infection of the skin on the scalp, eyebrows and eyelashes with a propensity for attacking hair shaft and follicles Telogen effluvium - Hair loss due to high grade fever, stress or trauma Trichotillomania - Hair-pulling disorder that involves recurrent, irresistible urges to pull out hair from the scalp, eyebrows, eyelashes and other parts of the body
Occurs when growth at the nail root (matrix) is interrupted by trauma OR any sever acute illness e.g. heart attack, measles, pneumonia, or fever. A. Terry’s nails B. Oil spot C. Beau’s lines D. Mee’s Lines
C. Beau’s lines Terry’s nails - Proximal white nail with narrow distal pink or brown band (0.5 to 3mm). The nail looks opaque and white, but the nail tip has a dark pink to brown band. Oil spot – Red brown discoloration of the nail bed (oil spot sign, salmon patch). Very common in Psoriasis Beau’s lines – Etiology: Temporary cessation of nail growth in the matrix. Transverse depression across the nail plate. These lines emerge from under the nail folds weeks later, and allow us to estimate when the patient was sick Mee’s Lines - Transverse type of true leukonychia caused by systemic disease. Causes: Arsenic poisoning
Which picture best illustrates depigmented patch?
(No answer)
Choose the best answer A. Fissure B. Excoriation C. Erosion D. Ulcer
C. Erosion
Is this a ___ A. Primary lesion B. Secondary lesion
B. Secondary lesion
Choose the best answer A. Vesicle B. Bullae C. Papule D. Nodule
B. Bullae
Is this a ___ A. Primary lesion B. Secondary lesion
A. Primary lesion
Choose the best answer A. Bullae B. Plaque C. Erosion D. Ulcer
D. Ulcer
Is this a ___ A. Primary lesion B. Secondary lesion
B. Secondary lesion
Choose the best answer A. Macule B. Patch C. Plaque D. Papule
C. Plaque
Is this a ___ A. Primary lesion B. Secondary lesion
B. Secondary lesion
Choose the best answer A. Vesicle B. Pustule C. Bullae D. Crust
B. Pustule
Is this a ___ A. Primary lesion B. Secondary lesion
A. Primary lesion
Choose the best answer A. Macule B. Patch C. Plaque D. Papule
A. Macule
Is this a ___ A. Primary lesion B. Secondary lesion
A. Primary lesion
This nail finding is commonly found in patients with psoriasis and alopecia areata. A. Beau’s lines B. Oil spot C. Koilonychia D. Nail pitting
D. Nail pitting
Usually occurs with over treated hair A. Trichoptilosis B. Trichostasis spinolosa C. Pili torti D. Pili annulati
A. Trichoptilosis Trichoptilosis - Split ends Trichostasis spinolosa - common but under-diagnosed disorder of hair follicle and is defined as a follicular disorder resulting from retention of numerous hairs surrounded by a keratinous sheath in dilated follicles Pili torti - Hair is twisted along the long axis Pili annulati - Alternating
Red brown discoloration of the nail bed, also known as salmon patch or oil spot is commonly found in this disease A. Acne vulgaris B. Atopic dermatitis C. Psoriasis vulgaris D. Seborrheic dermatitis
C. Psoriasis vulgaris
Nerve sheath tumors, axillary freckling, café au lait macules and lisch nodule on the iris are found in what disease? A. Marfan’s syndrome B. Von Recklinghausen’s disease C. Psedoxanthoma elasticum D. Ehlers Danlos syndrome
B. Von Recklinghausen’s disease Von Recklinghausen’s disease – also known as “neurofibromatosis 1” is a genetic disorder characterized by the growth of tumors on the nerves. The disease can also affect the skin and cause bone deformities.
18/M was brought to the emergency room for seizures. On P.E. you note the following findings. What is the most likely diagnosis? A. Neurofibromatosis B. Dermatomyositis C. Tuberous sclerosis D. Ehlers danlos disease
C. Tuberous sclerosis
56/M alcoholic, came in consulting for jaundice. During physical exam his fingernails where noted to appear as below. This condition has been associated with underlying pulmonary and CVS diseases as well as neoplastic, infectious and hepatobiliary diseases. What term is used to describe this condition? A. Koilonychias B. Terry’s nails C. Raquet nails D. Fingernail clubbing
D. Fingernail clubbing
A 28 year old male comes in for red scaly patches, non-pruritic, non-tender on his palms. His girlfriend who accompanies him has similar lesions on her palms. What laboratory exam should you request to confirm diagnosis A. Treponema pallidum Hemagglutination test B. Tzanck smear C. CBC D. KOH smear
A. Treponema pallidum Hemagglutination test Treponema pallidum Hemagglutination test - Treponema pallidum hemagglutination commonly known as TPHA is diagnostic test used to detect the dissolved amount of antibodies in the serum sample of a patient against the causative agents of syphilis. Tzanck smear - chickenpox skin test and the herpes skin test KOH smear – fungal infection
Casal’s necklace is characterized by a pigmented scaly rash over the C3 and C4 dermatome. It is often accompanied by dermatitis, dementia and diarrhea. It is associated with? A. Iron deficiency B. Zinc deficiency C. Vitamin C deficiency D. Vitamin B3 Deficiency
D. Vitamin B3 Deficiency
A first year medical student, sustained a small cut on her index finer while dissecting a cadaver who died of complications of Tuberculosis. She later developed a lichenified rough non healing plaque over the area. The most probable diagnosis is? A. Scrofuloderma B. TB verrucosa cutis C. Lupus vulgaris D. Papulonecrotic tuberculid
B. TB verrucosa cutis Scrofuloderma – direct extension of tubercle bacilli from an underlying infected lymph node or bone to the skin TB verrucosa cutis - Caused by exogenous re-infection of a previously sensitized individual Lupus vulgaris - Small sharply defined red brown lesions, with a scaly and friable surface Papulonecrotic tuberculid - chronic, recurrent, and symmetric eruption of necrotizing skin papules arising in crops, involving primarily the buttocks and extensor surfaces of the arms and legs. A hallmark of this condition is that lesions heal with varioliform and pitting scarring.
A 45 year old male is noted to have a string pulsations at the uvula synchronous with his heartbeat. Most probable condition? A. Aortic insufficiency B. Ludwig’s angina C. Vincent’s angina D. Quinsy
A. Aortic insufficiency
What disease gives patients this impassive, sphinx-like expression of the face? A. Scleroderma B. Parkinson’s disease C. Leprosy D. Grave’s disease
B. Parkinson’s disease