FINAL: Unit 4: Fetal Development+Congenital Heart Defects Flashcards
This system in terms of embryologic development
DEVELOPS EARLY
CARDIAC SYSTEM
Cardiac System
Embryologic Development
DAY 22 to 23
Fusion of the endocardial heart tubes
*THE HEART BEATS*
CARDIAC SYSTEM
Embryologic Dev
DAY 27
Heart starts circulating blood from the heart to the rest of the embryo
CARDIAC SYSTEM
Embryologic Dev
WEEK 8
4 Chambers of heart FULLY DEVELOPED
==> NORM heart function
CARDIAC SYSTEM
embryologic Dev.
WEEK 12***
Circulatory System is OPERATING
*NOTE: 12 weeks CARDIAC progress is 28-38wks progress for LUNGS
CARDIAC SYSTEM
Embryological Dev.
1st-2nd Trimester
HEART CAN FUNCTION
This system in terms of Embryologic Dev.
DEVELOPS LATE
PULMONARY SYSTEM
PULMONARY SYSTEM
Embryologic Dev.
WEEK 24*
Mucosal glands functional
Surfactant begins production (so the lungs can work—INC surf area)
PULMONARY SYSTEM
Embryologic Dev.
WEEK 28 TO TERM:
Surfactant production MATURES
PULMONARY SYSTEM
Embryologic Dev.
WEEK 36-40***
Alveoli appear, and surfactant reaches FULL MATURITY and is FUNCTIONAL
**REMEMBER—heart is fully working WAY BEFORE THIS (week 8 and by week 12 circulatory system is FULLY WORKING)
Fetal circulation is ________ from post-natal circulation
DIFFERENT
Fetal Circulation
Placenta
*Umbilical cord connects the placenta TO IVC and contains___________
Contains umbilical artery and umbilical vein
- Umbilical artery brings De-O2’d blood OUT of body
Fetal Circulation
Blood from the IVC goes where?
IVC—-> Rt. Atrium
*O2 comes from placenta
Fetal Circulation
Foramen Ovale
- permits MOST OF (90%) oxygenated blood ENTERING R. ATRIUM to pass INTO L. Atrium
- **SKIPS R. VENTRICLE + LUNGS
Fetal Circulation
Ductus Arteriosus
- Connects Aorta w/ the Pulm aa
-
SHUNTS most blood AWAY from lungs INTO aorta
- SKIPS LUNGS + L. SIDE OF HEART
- R. atrium–> R. vent–pulm aa–> aorta
Fetal Circulation
10% of blood goes where
10% goes to LUNGS only to nourish the developing lung tissue
BOTH Foramen Ovale and Ductus Arteriosus
Allow what?
- Allow blood to skip or shunt R. ventricle
OR
- Skip or shunt Lungs and L. side of heart
Fetal Circulation
More on blood vessels of Pulmonary circulation
*remember LUNGS for most part (only 10%) are SKIPPED
- Vessels of pulm circulation are vasoconstricted in the fetus
- blood traveling to and thru lungs is primarily used to nourish and develop lung tissue
Ductus Arteriosus
Blood b/w _______ and ________
Pulm aa & Aorta
Foramen Ovale
Blood b/w _________ and ________
R. and L. Atria
Umbilical Vein
O2’d blood into WHERE?
O2’d blood INTO IVC
**O2’d blood FROM PLACENTA
MORE PICS ON
O2’d blood from Placenta
Foramen Ovale–blood from Rt. atrium to L. atrium
Ductus Ateriosus–shunts blood AWAY from lungs
see pics
Fetal Circulation
Blood travels BACK TO PLACENTA via____________
Umbilical Arteries
*remember this is de-O2’d blood
Pediatric Development
Neonatal
Fetal fluid in lungs is squeezed out while passing thru birth canal.
Remaining fluid is Absorbed by capillaries and lymph
So that WHAT HAPPENS???
So infants lungs can expand w/ air w/ their first breath
-
Surfactant is necessary to maintain patent alveoli
- PREVENTS COLLAPSE***
What closes the foramen ovale after birth?
Closes w/ INCd Pressure in L. atrium
Ductus arteriosus begins to close when?
- w/in 24hrs of birth as lungs become filled w/ O2
-
BABY NOW BREATHING
- causes PO2 lvls to rise
-
BABY NOW BREATHING
Once baby PO2 lvls rise…
what happens to ventricles?
Shift from working in parallel to working in series
*R. vent slightly EARLIER vs. L. vent
Alveoli grow until _________ yrs old
8 yrs old
*NO smoking in the house****
MSK Cardiopulm Development in Infants
0-3 months
SHAPE OF THORAX:
DIRECTION OF RIBS:
PRIMARY MM’S USED FOR INSPIRATION:
Triangular
Horizontal
Diaphragm
MSK Cardiopulm Development in Infants
3 to 6 months
SHAPE OF THORAX:
DIRECTION OF RIBS:
PRIMARY MM’S USED FOR INSPIRATION:
RECTANGULAR
HORIZONTAL
DIAPHRAGM + ACCESS. MM’S
*Happens as infant gains UE strength
MSK Cardiopulm Development in Infants
6 to 12 months
SHAPE OF THORAX:
DIRECTION OF RIBS:
PRIMARY MM’S USED FOR INSPIRATION:
Rectangular
Angled Downward
Diaphragm + Intercostals
*NOTE: @ around age 2, should demo little to NO activation of access mm’s during quiet breathing—–> JUST DIAPHRAGM
Shape of Ribs
Infant—Triangle (0-3mos)
Adult or 12mo’s–Angled Downward
see pics
MOST COMMON BIRTH DEFECT
Congenital Heart Defects
CHD
Dx of cardiac dysf may be made when ?
Prenatally
@ Birth
T/O life
CHDs most often occurr when ?
8-10th wk of gestation
CHD
Causes:
- Genetics
- FAS, Fetal drugs
- Trisomy 21
- SMA
- Turners syndrome
- VATER assoc.
10% of children w/ CHDs also have other phys malformations
*********
CHD Categorization
2 Cats:
- Acyanotic–> pts are PINK
- Cyanotic–> pts are BLUE
Acyanotic vs. Cyanotic
see pics
CHD Categories
Acyanotic
pts are PINK
- Blood Shunts: L to R
- Blood to body: FULLY O2’D to lungs and body
- SV: LOW SV, heart works HARDER
- SaO2: NORM SaO2
- Pulm blood flow: INCd pulm blood flow
- Color: PINK
CHD Categories
Cyanotic
pts are BLUE
- Blood Shunts: R to L
- Blood to Body: UNoxygenated blood returned to body
- SV: GOOD quality SV
- SaO2: 15-30% BELOW NORM
- *RBCs: INCd RBC formation
- *Viscosity: INCd blood viscosity—> risk of CVA
- Color: BLUE
Acyanotic vs. Cyanotic
Common Lesions
see pics
Common Acyanotic Lesions :
- Atrial Septal Defects- ASDs
- Ventricular Septal Defects -VSDs
- Atrioventricular Septal Defects-AVSDs
- Patent Ductus Arteriosus- PDA
- Coartication of the Aorta
- Pulmonary Stenosis
- Aortic Stenosis
*Alfred Ventured Ahead of Paula Cuz Paula Abdul
Common Cyanotic Lesions:
- Tetralogy of Fallot
- Transposition of the Great Arteries
- Tricuspid Atresia
- Pulmonary Atresia
- Truncus Arteriosus
- Total Anomalous Pulmonary Venous Return
- Hypoplastic Left-Sided Heart Syndrome- HLHS
*Triple T, P, Double T, H
Acyanotic
Atrial Septal Defect
ASD
what is it
- HOLE in septum b/w the atria
- persistent (long term) foramen ovale
Acyanotic
Atrial Septal Defect
ASD
Allows _______ blood to flow from _______ to _______
Allows oxygenated blood to flow from L atria to R atria
- Mixerespirated blood
- Stresses heart===> CHF
- >80% CLOSE in first yr w/out sx
Acyanotic
Atrial Septal Defect
ASD
S/S
- Murmur
- racing heart beat
- Enlarged pulm aa
Acyanotic
Atrial Septal Defect
ASD
>80% close w/out sx BUT
What is the Sx intervention?
PATCH placed via open heart sx OR cath proc.
Acyanotic Defects
Ventricular Septal Defect
VSDs
Explain generally
- Opening in Septum b/w L and R ventricle
- Blood flows b/w ventricles
- HEART MUST WORK HARDER TO PUMP BLOOD TO BODY
Acyanotic Defects
Ventricular Septal Defect
VSDs
LARGE DEFECTS…
- LG. defects may lead to:
- bacterial endocarditis
- pulm vascular obstructive dis.
- aortic regurgitation
- INCd incidence of lower resp tract infections
- CHF
Acyanotic Defects
Ventricular Septal Defect
VSDs
S/S
- Murmur
- fatigue
- INCd HR
- poor growth/feeding
- irritability
- restlessness
- rapid breathing
Acyanotic Defects
Ventricular Septal Defect
VSDs
Tx:
- Watch/Wait: may spontaneously close
- Sx: close via patch w/ open heart sx
Acyanotic Defects
Atrioventricular Septal Defect
AVSDs
*BOTH PLACES
Explain generally…
- Persistent (long term) foramen ovale AND ventricle septal defect w/ incomplete valve formation
- 15-40% children w/ Downs/Trisomy 21
Acyanotic Defects
AtrioVentricular Septal Defect
AVSDs
S/S
- Pulm HTN—-usually assoc’d w/ R.side HF
- lung congestion
- HF
Acyanotic Defects
AtrioVentricular Septal Defect
AVSDs
Tx:
- Sx usually required w/in first few months of life
Acyanotic Defects
Patent Ductus Arteriosus
PDA
“Open Passageway”
*opening b/w Pulm aa & Aorta
Describe generally…
- NORMALLY closes w/in 5-14 days after birth bc changes in prostaglandin lvls w/ INC O2 lvls
-
Often assoc’d w/:
-
prematurity/respiratory distress syndrome/hyaline membrane dis.
- —> Hypoxia: O2 lvls NEVER HIGH ENOUGH to signal closure
-
prematurity/respiratory distress syndrome/hyaline membrane dis.
Acyanotic Defects
Patent Ductus Arteriosus
PDA
“Open Passageway”
*opening b/w Pulm aa & Aorta
S/S
*vary based on SIZE of opening
-
LARGE:
- Compensatory tachycardia + INCd RR
- poor wt. gain
-
SMALL:
- asymptomatic
Acyanotic Defects
Patent Ductus Arteriosus
PDA
“Open Passageway”
*opening b/w Pulm aa & Aorta
Tx:
- Minimally invasive sx closure
- Med mgmt w/ indomethacin
Acyanotic Defects
Coartication (narrowing) of the Aorta
Explain Generally….
AKA 2* HTN
- Narrowing of the Aorta after it branches off to the UPPER BODY
- Obstructed of blood flow to LOWER BODY
- INCd work on L. vent to pump
- Can lead to CHF
Acyanotic Defects
Coartication (narrowing) of the Aorta
S/S
- INCd RR
- INCd sweating
- DECd growth
- DECd endurance
- murmur
Acyanotic Defects
Coartication (narrowing) of the Aorta
Tx:
- Cath to dilate
- Stent to open
-
Sx:
- REMOVE portion of aorta and sew back together or enlarge w/ patch
- MAY RE-OCCUR
Acyanotic Defects
PULMONARY STENOSIS
IN GENERAL….
- Fused, thickened or missing leaflets of pulm valve causing OBSTRUCTION
- INCs work on Rt. ventricle (bc this is where Pulm valve leaves) to pump blood to lungs
Acyanotic Defects
PULMONARY STENOSIS
S/S
- Fatigue
- murmur
- Rare cases have chest pain
Acyanotic Defects
PULMONARY STENOSIS
Dx:
- ECG
- Chest X-ray
- SpO2
- Cath
- MRI
Acyanotic Defects
PULMONARY STENOSIS
Tx:
- DEPENDS on anatomy and severity
- Cath
-
Sx:
- Valvotomy
- homograft (self) valve
- New valve
Acyanotic Defects
AORTIC STENOSIS
In general…
- Fused, Thickened, missing leaflets of Aortic valve (its IN the name of the defect as what it IS*)
- Obstruction from LEFT vent to aorta (bc this is where Aortic valve leads)
- INCd work on LEFT ventricle to pump blood to body (bc this is where Aortic valve is**)
Acyanotic Defects
AORTIC STENOSIS
S/S
MOST ALL ACYANOTIC DEFECTS HAVE SAME S/S***
- Fatigue
- Murmur
- Rarely chest pain
- fainting
- arrhythmias
Acyanotic Defects
AORTIC STENOSIS
Dx:
- Murmur
- ECG
- ECHO
- chest x-ray
- SpO2
- Cath
- MRI
Acyanotic Defects
AORTIC STENOSIS
Tx:
Depends on severity
- Balloon Valvuloplasty via cath
-
Sx:
- artificial valve OR Ross proc.
CYANOTIC DEFECTS
these pts are______
BLUE
“cyanotic”
Cyanotic Defects
Tetrology or Fallot
Tetra==4***
COMBINATION of defects:
- VSDs
- Aortic Override
- Pulm Stenosis
- R. Ventricular Hypertrophy
Cyanotic Defects
Tetrology or Fallot
Tetra==4***
What is it??
- 50% of Cyanotic defects***
- DECd blood flow to the lungs
- POORLY oxygenated blood (bc SO much going on think about COMBO*) pumps out thru Aorta
- *Degree of Cyanosis depends on pulm stenosis
Cyanotic Defects
Tetrology or Fallot
Tetra==4***
S/S
Cyanosis
murmur
*clubbing
‘Tet spell”
Cyanotic Defects
Tetrology or Fallot
Tetra==4***
Tx:
- Sx:
- repair VSD
- dilate pulm valve (rt. vent–pulm aa)
Cyanotic Defects
Transposition of the Great Arteries
“Transposition” meaning everything is all OUT OF POSITION***
EXPLAIN
- Aorta comes out of R. Ventricle—-NOT GOOD
- Pulm artery comes out of L. Ventricle—-NOT GOOD
- NO COMMUNICATION B/W SYSTEMIC AND PULMONARY CIRCULATIONS***
Cyanotic Defects
Transposition of the Great Arteries
S/S
- Cyanosis
- INCd RR
- poor feeding/Wt. Gain/appetite
Cyanotic Defects
Transposition of the Great Arteries
Dx:
- Fetal ECHO
- ECG
- Cath
- MRI
- SpO2
- Chest x-ray
Cyanotic Defects
Transposition of the Great Arteries
Tx:
- ALL will need open heart sx for arterial switch repair
- *Arrhythmias or vent dysf’s may develop later in life
Cyanotic Defects
Tricuspid Atresia
*IN NAME—–has to be something w/ Tricuspid Valve*****
General…
- Tricuspid Valve (R. Atria–>R. Vent) fails to develop OR is patent
- SMALLER than normal R. Vent
- ALWAYS have ASD
- SOMETIMES VSD
- ***only 1 functioning ventricle
Cyanotic Defects
Pulmonary Atresia
**IN NAME—–HAS to be something w/ Pulmonary valve (Rt. Vent—> Pulm aa)
General….
- Abnorm. formed pulm valve
- Block of blood from R. SIDE of heart TO lungs
- **often assoc’d w/ VSD
Cyanotic Defects
Pulmonary Atresia
S/S
- cyanosis
- poor feeding/wt. gain
- SOB
Cyanotic Defects
Pulmonary Atresia
Dx:
- Fetal US
- ECG
- ECHO
- SpO2
- chest x-ray
- MRI
Cyanotic Defects
Pulmonary Atresia
Tx:
- Balloon valvuloplasty via Cath.
- Open heart sx
- patch or Shunt
Cyanotic Defects
Truncus Arteriosus
General….
- Missing normal separation of the Aorta and Main Pulm aa during fetal development
- RESULTS IN R. and L. vents empty into a single Lg. vessel
-
Single GREAT ARTERY arises from the Vents
- carries BOTH pulmonary and systemic blood flow
*VSD ALWAYS present
*Heart functions as a SINGLE VENTRICLE
Cyanotic Defects
Truncus Arteriosus
Tx
Sx repair is req’d for correction
Cyanotic Defects
Total Anomalous Pulmonary Venous Return
General….
- Pulm veins attach to the R. Atrium OR to other veins that drain into the R. Atrium
Cyanotic Defects
Total Anomalous Pulmonary Venous Return
S/S
- Pulm congestion
- cyanosis
- HF
Cyanotic Defects
Total Anomalous Pulmonary Venous Return
*ASD may also be present…..what does this mean?
*ASD may also be present—-> Aids R. Atrium decompression
Cyanotic Defects
Total Anomalous Pulmonary Venous Return
Sx:
- Anastomosis (surgical joining) of the pulm veins TO L. atrium
- PERFORMED EARLY AS POSS.
CYANOTIC DEFECTS
HYPOPLASTIC LEFT-SIDED HEART SYNDROME
HLSHS
Includes 3 things:
- Hypoplastic (underdeveloped) L. Vent
- Aortic and Mitral Valve stenosis (narrowing) OR atresia (complete closure)
- Coartication of the Aorta
Cyanotic Defects
Hypoplastic (underdeveloped) L. Sided Heart Syndrome
HLHS
S/S
- may be MINIMAL while PDA (Patent Ductus Arteriosus) is open
- cyanosis
- poor feeding/wt. gain
- INCd work of breathing
- lethargy
Cyanotic Defects
Hypoplastic (underdeveloped) L. Sided Heart Syndrome
HLHS
Dx:
- fetal echo
- ECG
- ECHO
- chest x-ray
- SaO2
- cath
- MRI
Cyanotic Defects
Hypoplastic (underdeveloped) L. Sided Heart Syndrome
HLHS
Tx:
- Prostaglandin E to maintain PDA (Patent Ductus Arteriosus)
- Mech. Vent may be req’d until sx or heart transplant can occur
- 3 staged sx procedure or transplant
Pulmonary Patho of infancy or childhood
Abnorm Development
- **Assess chest wall****
- Looking for weakness and/or Tone imbalance:
- Incomplete elongation of ribcage
- Rib cage flaring—–ant or lat.
- LOWER resting pos. of diaphragm
- Kyphotic posture
- Pectus excavatum
- Abnorm dev of the chest can cause DEC in pulm function
Soda Pop Model
*of Postural Support
“If you can’t breathe, you can’t function.”
Mary Massery
Soda Pop Model
Ex. POOR POSTURE
EXTREME EXAMPLE
SEE PICS
COMMON Pediatric Pulmonary Dx’s
3 NEW
Rest you already know!!!!!
- Meconium (baby’s poop in womb) Aspiration Syndrome
- SIDS
- Tracheoesophageal Fistula
- Asthma
- Resp. Distress Syndrome/Hyaline Memb Dis.
- Pectus deformities
- Bronchopulm Dysplasia (BPD)
- Broncholitis Obliterans (BO)
- Cystic Fibrosis (OLD)
- Lung Transplants
Meconium Aspiration Syndrome
MAS
What is Meconium?
contents of fetal/newborn bowel
Meconium Aspiration Syndrome
MAS
WHEN occur?
W/ FIRST postnatal breaths
Meconium Aspiration Syndrome
MAS
Reversible when?
Reversible IF airways are suctioned immediately @ birth
Meconium Aspiration Syndrome
MAS
Can Cause:
- Atelectasis
- Tension pneumothorax—-WORSE KIND (one-way door)
- Persistent (long term) Pulm HTN
- Bronchiolitis
- Pneumonitis
Meconium Aspiration Syndrome
MAS
Tx:
- Pulm hygiene
- Supplemental Oxygen (PRN)
- Assisted ventilation (PRN)
Sudden Infant Death Syndrome
SIDS
what is it?
Sudden, unexpected death during sleep of an otherwise healthy infant
*MAY be linked be w/ respiration infection and brain stem dev.
SIDS
Risk Factors:
- Male infant
- LOW birth wt
- active resp. infection
- sleeping on soft surfs
- sharing bed w/ adults/siblings/pets
- overheating
- age (MOST RISK @ 2-3mos old
- prematurity w/ immature neural development
- 2nd hand smoke
- maternal age <20
- family hx
- inad. prenatal care
SIDS and “Back to Sleep”
Sleep in SUPINE
*incidence DECd by >50% since “Back to Sleep”
SIDS
PT Role
Back to Sleep/Tummy to Play
SIDS
Back to Sleep/Tummy to Play
Promoting compliance???
5 S’s****
1. Shush
2. Sound
3. Swaddle
4. Swing
5. Suck
Tracheoesophageal Fistula
- .02% of births
-
Abnorm connection b/w esophagus and trachea
- —–> Causes fluids to pass thru esophagus INTO trachea and lungs
- **Req’s Sx
Tracheoesophageal Fistula
Commonly seen w/:
Trisomy 13, 18 and 21
VATER syndrome
heart defects
defects of kidney + urinary tract
VATER syndrome
V: Vert abnormal
A: Anal Atresia
T: Trachea
E: Esophagus
R: Renal
NORM Vital Signs for Various Ages
Ranges + Avgs
RPE Also
see pics
Tx Ideas for CHDs and Pediatric Pulmonary Dx’s
- Lateral costal breathing manual tech.
- put your hand where YOU want them to breathe INTO
- Diaphragmatic breathing QUICK STRETCH
- RIGHT AFTER LOOOONG EXHALE JUST BEFORE INHALE!!!
- Diaphragmatic breathing w/ visualization
- IMTs
- Flexibility
- Strength
- Posture
- Pulm toileting
- Functional Mobility
- Endurance training—-OBSTACLE COURSES!!!