FINAL: Unit 4: Fetal Development+Congenital Heart Defects Flashcards
This system in terms of embryologic development
DEVELOPS EARLY
CARDIAC SYSTEM
Cardiac System
Embryologic Development
DAY 22 to 23
Fusion of the endocardial heart tubes
*THE HEART BEATS*
CARDIAC SYSTEM
Embryologic Dev
DAY 27
Heart starts circulating blood from the heart to the rest of the embryo
CARDIAC SYSTEM
Embryologic Dev
WEEK 8
4 Chambers of heart FULLY DEVELOPED
==> NORM heart function
CARDIAC SYSTEM
embryologic Dev.
WEEK 12***
Circulatory System is OPERATING
*NOTE: 12 weeks CARDIAC progress is 28-38wks progress for LUNGS
CARDIAC SYSTEM
Embryological Dev.
1st-2nd Trimester
HEART CAN FUNCTION
This system in terms of Embryologic Dev.
DEVELOPS LATE
PULMONARY SYSTEM
PULMONARY SYSTEM
Embryologic Dev.
WEEK 24*
Mucosal glands functional
Surfactant begins production (so the lungs can work—INC surf area)
PULMONARY SYSTEM
Embryologic Dev.
WEEK 28 TO TERM:
Surfactant production MATURES
PULMONARY SYSTEM
Embryologic Dev.
WEEK 36-40***
Alveoli appear, and surfactant reaches FULL MATURITY and is FUNCTIONAL
**REMEMBER—heart is fully working WAY BEFORE THIS (week 8 and by week 12 circulatory system is FULLY WORKING)
Fetal circulation is ________ from post-natal circulation
DIFFERENT
Fetal Circulation
Placenta
*Umbilical cord connects the placenta TO IVC and contains___________
Contains umbilical artery and umbilical vein
- Umbilical artery brings De-O2’d blood OUT of body
Fetal Circulation
Blood from the IVC goes where?
IVC—-> Rt. Atrium
*O2 comes from placenta
Fetal Circulation
Foramen Ovale
- permits MOST OF (90%) oxygenated blood ENTERING R. ATRIUM to pass INTO L. Atrium
- **SKIPS R. VENTRICLE + LUNGS
Fetal Circulation
Ductus Arteriosus
- Connects Aorta w/ the Pulm aa
-
SHUNTS most blood AWAY from lungs INTO aorta
- SKIPS LUNGS + L. SIDE OF HEART
- R. atrium–> R. vent–pulm aa–> aorta
Fetal Circulation
10% of blood goes where
10% goes to LUNGS only to nourish the developing lung tissue
BOTH Foramen Ovale and Ductus Arteriosus
Allow what?
- Allow blood to skip or shunt R. ventricle
OR
- Skip or shunt Lungs and L. side of heart
Fetal Circulation
More on blood vessels of Pulmonary circulation
*remember LUNGS for most part (only 10%) are SKIPPED
- Vessels of pulm circulation are vasoconstricted in the fetus
- blood traveling to and thru lungs is primarily used to nourish and develop lung tissue
Ductus Arteriosus
Blood b/w _______ and ________
Pulm aa & Aorta
Foramen Ovale
Blood b/w _________ and ________
R. and L. Atria
Umbilical Vein
O2’d blood into WHERE?
O2’d blood INTO IVC
**O2’d blood FROM PLACENTA
MORE PICS ON
O2’d blood from Placenta
Foramen Ovale–blood from Rt. atrium to L. atrium
Ductus Ateriosus–shunts blood AWAY from lungs
see pics
Fetal Circulation
Blood travels BACK TO PLACENTA via____________
Umbilical Arteries
*remember this is de-O2’d blood
Pediatric Development
Neonatal
Fetal fluid in lungs is squeezed out while passing thru birth canal.
Remaining fluid is Absorbed by capillaries and lymph
So that WHAT HAPPENS???
So infants lungs can expand w/ air w/ their first breath
-
Surfactant is necessary to maintain patent alveoli
- PREVENTS COLLAPSE***
What closes the foramen ovale after birth?
Closes w/ INCd Pressure in L. atrium
Ductus arteriosus begins to close when?
- w/in 24hrs of birth as lungs become filled w/ O2
-
BABY NOW BREATHING
- causes PO2 lvls to rise
-
BABY NOW BREATHING
Once baby PO2 lvls rise…
what happens to ventricles?
Shift from working in parallel to working in series
*R. vent slightly EARLIER vs. L. vent
Alveoli grow until _________ yrs old
8 yrs old
*NO smoking in the house****
MSK Cardiopulm Development in Infants
0-3 months
SHAPE OF THORAX:
DIRECTION OF RIBS:
PRIMARY MM’S USED FOR INSPIRATION:
Triangular
Horizontal
Diaphragm
MSK Cardiopulm Development in Infants
3 to 6 months
SHAPE OF THORAX:
DIRECTION OF RIBS:
PRIMARY MM’S USED FOR INSPIRATION:
RECTANGULAR
HORIZONTAL
DIAPHRAGM + ACCESS. MM’S
*Happens as infant gains UE strength
MSK Cardiopulm Development in Infants
6 to 12 months
SHAPE OF THORAX:
DIRECTION OF RIBS:
PRIMARY MM’S USED FOR INSPIRATION:
Rectangular
Angled Downward
Diaphragm + Intercostals
*NOTE: @ around age 2, should demo little to NO activation of access mm’s during quiet breathing—–> JUST DIAPHRAGM
Shape of Ribs
Infant—Triangle (0-3mos)
Adult or 12mo’s–Angled Downward
see pics
MOST COMMON BIRTH DEFECT
Congenital Heart Defects
CHD
Dx of cardiac dysf may be made when ?
Prenatally
@ Birth
T/O life
CHDs most often occurr when ?
8-10th wk of gestation
CHD
Causes:
- Genetics
- FAS, Fetal drugs
- Trisomy 21
- SMA
- Turners syndrome
- VATER assoc.
10% of children w/ CHDs also have other phys malformations
*********
CHD Categorization
2 Cats:
- Acyanotic–> pts are PINK
- Cyanotic–> pts are BLUE
Acyanotic vs. Cyanotic
see pics
CHD Categories
Acyanotic
pts are PINK
- Blood Shunts: L to R
- Blood to body: FULLY O2’D to lungs and body
- SV: LOW SV, heart works HARDER
- SaO2: NORM SaO2
- Pulm blood flow: INCd pulm blood flow
- Color: PINK
CHD Categories
Cyanotic
pts are BLUE
- Blood Shunts: R to L
- Blood to Body: UNoxygenated blood returned to body
- SV: GOOD quality SV
- SaO2: 15-30% BELOW NORM
- *RBCs: INCd RBC formation
- *Viscosity: INCd blood viscosity—> risk of CVA
- Color: BLUE
Acyanotic vs. Cyanotic
Common Lesions
see pics
Common Acyanotic Lesions :
- Atrial Septal Defects- ASDs
- Ventricular Septal Defects -VSDs
- Atrioventricular Septal Defects-AVSDs
- Patent Ductus Arteriosus- PDA
- Coartication of the Aorta
- Pulmonary Stenosis
- Aortic Stenosis
*Alfred Ventured Ahead of Paula Cuz Paula Abdul
Common Cyanotic Lesions:
- Tetralogy of Fallot
- Transposition of the Great Arteries
- Tricuspid Atresia
- Pulmonary Atresia
- Truncus Arteriosus
- Total Anomalous Pulmonary Venous Return
- Hypoplastic Left-Sided Heart Syndrome- HLHS
*Triple T, P, Double T, H
Acyanotic
Atrial Septal Defect
ASD
what is it
- HOLE in septum b/w the atria
- persistent (long term) foramen ovale