Final: Tumors and Tumor Like Processes Flashcards

1
Q

What is the most common source of osteoblastic metastatic carcinoma in adult females?

A

Breast CA

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2
Q

The 3 common causes of solitary sclerotic vertebral body/ivory vertebra

A
IHOP:
I: Ivory
H: Hodgkin's lymphoma
O: Osteoblastic mets
P: Paget's dz
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3
Q

Is it common to find a tumor involving a joint?

A

No

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4
Q

Is multiple myeloma more common in the vertebral body or neural arch?

A

Vertebral body

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5
Q

What malignancy demonstrates as a cold bone scan?

A

Multiple Myeloma

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6
Q

What is the common age range of primary osteosarcoma?

A

10-25 y/o

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7
Q

What is the most dense (white on x-ray) primary malignant tumor?

A

Multiple Myeloma

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8
Q

What is the difference between sunburst and onion skin appearance?

A

Sunburst: spoked wheel –> osteosarcoma

Onion skin: Ewing’s sarcoma

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9
Q

Which part of the long bone is commonly involved in osteosarcoma?

A

Metaphysis

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10
Q

What is codman’s triangle?

A

A periosteal rxn seen w/ aggressive bone lesions. Periosteum does not have time to ossify w/ shells of new bone so only edge of raised periosteum will ossify.

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11
Q

Why is Ewing’s sarcoma commonly found in the dyaphysis of long bone?

A

It is a marrow cell tumor.

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12
Q

What is a geographic lytic appearance and does it suggest more benign or aggressive neoplasms? What are the other two lytic appearances of tumors?

A

Destructive lytic bone lesions. Benign.

Motheaten/permeative
Blowout

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13
Q

Which condition presents as a solitary exostosis that points away from the nearest joint?

A

Osteochondroma. MC benign bone tumor.

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14
Q

Incidence of malignant transformation in osteochondroma and hereditary multiple exostosis

A

Osteochondroma = 1%

Hereditary multiple exostosis: 20%

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15
Q

What is a corduroy vertebra?

A

Vertical lines in vertebral bodies

–> Ddx with Paget’s dz

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16
Q

Is spinal hemangioma commonly solitary or polyostotic?

A

Solitary

17
Q

Which is the most common benign bone tumor of the spine?

A

Hemangioma

18
Q

Is a bone island symptomatic?

A

Usu asx

DDx: osteoblastic mets, osteoid osteoma

19
Q

Which benign tumor cassically demonstrates as pain worst at night and easily relieved by aspirin?

A

Osteoid osteoma

20
Q

Which part of the bone is usu involved with osteoid osteoma?

A

Cortical

21
Q

What is the appearance of the tumor matrix in the endochondroma?

A

Geographic lytic, expansile, thinned cortex, endosteal scalloping, most central, calcification in 50%

22
Q

What is multiple endochondromatosis called?

A

Ollier’s dz

23
Q

What is the most common location of fibrous cortical defect?

A

Lower extremity

24
Q

What is a fallen fragment sign associated with?

A

Piece of cortex breaks off and falls into the fluid of the cyst (Assoc w/simple bone cyst)

25
Q

Which benign bone tumor is named according to its appearance rather than its histological composition?

A

Aneurysmal bone cyst: acute onset w/pain and rapid progression. MC tumor of posterior arch

26
Q

Radiographic appearance of endochondroma

A
Enchondroma: Stippled calcification
•    Geographic lytic
•    Expansile
•    Thinned  cortex,  endosteal  scalloping
•    Metaphyseal-diaphyseal
•    Most  central
•    Calcification  in  50%
•    No periosteal reaction; no soft tissue mass
27
Q

Radiographic appearance of simple bone cyst

A

Simple bone cyst:
• Geographic; lytic; maybe loculated (multiple pockets)
• Broad based at physis, narrows toward diaphysis
• Bone expansion, but not beyond physis diameter
• “Fallen fragment” sign with fracture

28
Q

Radiographic appearance of aneurysmal bone cyst

A
Aneurysmal bone cyst: 
•    Expansile
•    Lytic, septated
•    Eccentric
•    Markedly  thinned  cortex
•    Metaphyseal, may extend to epiphysis (only benign tumor to cross growth  plate)
•    Periosteal  response  more  common
29
Q

Radiographic appearance of osteochondroma

A
Osteochondroma:
•    Bony  exostosis:  cortex  continuous  with  host  bone;  normal  trabeculae 
•    Cartilaginous  cap  may  calcify
•    Project  away  from  joint
•    Sessile produces asymmetric widenin
30
Q

Is giant cell tumor painful? Is it malignant?

A

Yes, painful

Benign

31
Q

Is Paget’s dz monostotic or polyostotic?

A

Polyostotic, many bones involved

32
Q

Radiographic features of Paget’s dz in a long bone

A

Ivory vertebrae, opaque or lucent (increased or decreased density), thick cortex, coarsened trabeculae, subarticular extension, pseudofractures, deformities, saber shin deformity, bone expansion, polyostoic, R side > L side
Femur and Tibia: Blade of grass or candle flame appearance; V lesion