Final Review Flashcards
What are the allosteric inhibitors of hexokinase?
G-3-P (competitive) and ATP
What are the allosteric inhibitors of PFK-1?
ATP and citrate
What are the allosteric activators of PFK-1?
ADP, AMP, F-2,6-P
What are the allosteric inhibitors of glyceraldehyde-3-phosphate dehydrogenase?
NAD+ (regulated by)
What are the allosteric inhibitors of pyruvate kinase?
Acetyl CoA and ATP
What are the allosteric activators of pyruvate kinase?
F-1,6-biphosphate + AMP
What type of enzyme is an aldolase?
Lyase
What type of enzymes is a kinase?
Transferase
What type of enzyme is a dehydrogenase?
Oxidoreductase
What type of enzyme is a mutase?
Isomerase
What type of enzyme is enolase?
Lyase
What are the three allosteric regulators of the TCA cycle?
- Citrate synthase
- Isocitrate dehydrogenase
- a-ketoglutarate dehydrogenase
What are the allosteric inhibitors of citrate synthase?
Succinyl-CoA, citrate, ATP, NADH
What are the allosteric inhibitors of isocitrate dehydrogenase?
ATP and NADH
What are the allosteric activators of isocitrate dehydrogenase?
ADP and NAD+