Final (Old material) Flashcards
Accurate temperature measurement in children
Rectal thermometer in children < 3 y.o.
Oral thermometer in children > 5 y.o.
Axillary, temporal, tympanic thermometers are less accurate
Normal rectal temperature range
- 9-100.2F
(36. 6-37.9C)
T/F Degree of fever correlates with severity of illness
False. The general appearance is a stronger indicator. So a low temperature does not negate a serious bacterial illness.
Fever mgmt recs: How? Pharm vs non pharm
- Non-pharmacological -
- hydration
- appropriate clothing and ambient temp
- tepid water baths for temp > 104F
- Do not allow shivering
- Never use alcohol or ice baths
- Pharm mgmt -
- acetaminophen 10-15 mg/kg/dose q 4-6 hours (FIRST LINE)
- ibuprofen (children age 6+ months)
- Temp < 102.5F: 5 mg/kg/dose q 6-8 hours
- Temp >=102.5F: 10 mg/kg/dose q6-8 hrs
- No aspirin, no naproxen
- alternating acetaminophen and ibuprofen may increase risk of med error/toxicity
Causes of fever in neonates (2)
Congenital or acquired infections
1) late onset group B strep
2) acquired anatomic or physiologic dysfunction, i.e. renal
Causes of fever in all children (11)
- bacterial, fungal, parasitic, or viral infection
- vaccines
- biologic agents
- tissue damage
- malignancy - neoplasms
- drugs
- collagen-vascular disorders
- endocrine disorders
- inflammatory disorders - teething
- environmental - heat stroke
- if temp > 105.8F - likely CNS dysfunction such as malignant hyperthermia, drug fever, heat stroke
infants with meningitis don’t present with?
nuchal rigidity
do thorough neuro exam, fontanelles,
Definition of fever without a focus/source
- Acute fever of unknown etiology after examining child that is < 2 years old/24 months
- < 24 months = higher risk for SBI, esp < 3 months old = need workup
Most infants < 90 days have causative agent as ________, however, still need to rule out _____ disease so require a _____ work-up.
- Viral
- Bacterial
- Sepsis
< 24 months/2 yrs → Greatest risk of unsuspected occult bacteremia w/ E. coli.
What are common SBIs with no clinical sx’s? (3)
- UTI
- PNA
- bacteremia
Any child < 3 years old who is ill-appearing should have the following tests…(10)
- CBC w/diff
- Glucose
- CRP
- PCT
- blood cultures
- CSF testing
- UA and culture
- CXR
- Stool cx if diarrhea with blood or mucus in stool
- If in season, rapid testing for influenza/RSV/enterovirus
Red Flags - Infants who need to be admitted to the hospital and for serious bacterial infections: (16)
- Prematurity
- Underlying health conditions
- Parents are unreliable historians and/or caretakers
- Ill or toxic-appearing
- Skin color is ashen, blue, mottled, or pale
- Lethargic, weak
- High-pitched cry, decreased response
- Poor feeding
- tachypnea or tachycardia
- Chest/abdominal retractions
- Petechiae
- Seizure
- Capillary refill > 3 seconds
- decrease UO
- Bulging fontanel
- Non-blanching skin rash
evaluation of fever in young infants 29-60 days (1-2 months)
- ill appearing, get:
- septic workup, admit
- healthy appearing, get:
- CBC/diff
- Blood culture
- UA and urine culture
- PCT
- CRP
- CXR if signs of respiratory symptoms/not clearly bronchiolitis
- if low criteria [well appearing, full term, no system anti, normal labs etc]:
- sent home with strict f/u in 12-24 hrs, seek care if worsens, or if culture is +, if unreliable caretakers
- high criteria:
- Admit and further workup
evaluation of fever in 60-90 day (2-3 month) infant
- if ill appearing = sepsis workup, admit
- if healthy appearing, get:
- CBC/diff
- Blood culture
- UA + culture
- PCT
- if immunized in past 24 hrs & temp < 101.5F, never mind!
all infants this age that has fever need urinalysis
all infants < 3 months to rule out UTI
Subjective data - Current medications - all children (2)
- Immunization history (esp. recent immunizations)
- Meds used to treat fever, illness
Definition: fever of unknown origin
- 100.5F at least once daily x 14 or more days and dx not apparent after careful hx, PE, and noninvasive tests
- temp > 101+ on several occasions > 3 weeks and no dx with 1 week intense investigation
FUO - usually ______, may require _______ consult; ___% self-resolve
- viral
- ID
- 25
Define prolonged fever
single illness in which fever that exceeds that than which is expected for the clinical diagnosis
Sometimes may have prolonged fever that precedes FUO
common causes of FUO in < 6 yrs (6)
- UTI/pyelo
- respiratory infection
- local infection such as abscess
- Juvenile arthritis
- leukemia (rare)
- COVID
common causes FUO in adolescents:
- TB
- Inflammatory bowl disease
- lymphoma
- Autoimmune diseases
- Covid
- chlamydia
Work-up/labs in FUO (16)
- To be done in primary care
- CBC w/ diff
- ESR
- CRP
- UA and culture
- blood cultures
- CMP
- liver and renal function tests
- LDH
- RAF
- ANA
- uric acid levels
- PPD/mantoux skin test or CXR
- sinus XR, mastoid XR, GI XR
- echocardiogram
Kawasaki criteria
persistent fever for at least 5 days PLUS > 4 of these:
- bilateral conjunctival injection, nonpurluent
- change in lips and oral cavity (red, cracked strawberry tongue, diffuse redness mucosa)
- cervical lymphadenopathy (unilateral); > 1.5 cm nodes
- polymorphous exanthema rash in extremities, trunk, perineal regions
- changes in peripheral extremities (edema hands & feet) or perineal area
can also be incomplete who lack classic sx’s = coronary artery abn can confirm dx too
Kawasaki labs if incomplete KD dx
- based on symptoms
A. fever >= 5 days + 4 of the following:
- a. dry, cracked mucous membranes (90% incidence)
- b. maculopapular (or morbilliform) rash, or macular rash in perianal area (70-90%)
- c. Changes in extremities such as edema of hands and feet, erythema of palms and soles (acute), or desquamation of fingers and toes (subacute)
- d. bilateral, non-purulent conjunctivitis
- e. strawberry tongue
- f. Asymmetric ant. cervical lymphadenopathy
- g. irritability h. ST, gallop rhythms, innocent flow murmurs, murmurs of aortic or mitral regurgitation
- incomplete dx include:
albumin > 3
urine > 10 WBC
platelet > 450,000 after 7 days of fever
anemia
total WBC > 15,000
elvation of ALT
coronary artery abnormalities (confirms)
Imaging studies in Kawasaki
- Echo (baseline then repeat 2 wks, then 6-8 wks)
- EKG
Kawasaki mgmt
EARLY DIAGNOSIS TO PREVENT ANEURYSMS!
Treatment more effective before 10th day of illness
IVIG to control vascular inflammation
high dose aspirin (antiplatelet effect) - need inactiavted flu shott
baseline echo, then 2 wks, then 6-8 wks after onset
delay live vaccines at least 11 months after admin of IVIG
Kawasaki Disease - Stage 1 (acute)
- Lasts about 10 days
- Perisistent high fever for >= 5 days - may not respond to antipyretics, abx
- PLUS Conjunctival hyperemia, edema of hands and feet, polymorphous erythematous rash, unilateral lymphadenopathy
- strawberry tongue = classic (no ulcers/pharyngeal exudate)
- lymph node > 1.5cm (non tender to slightly firm)
- tachycardia, gallop rhythms, flow murmurs, mitral regurg or aortic regurg
Kawasaki Disease - Stage 2 (subacute)
- Day 11-25
- Fever disappears
- Most symptoms resolve
- Desquamation of fingers, toes, groin, and perianal region
- Thrombocytosis
- Coronary aneurysms REFER TO ECHO!
- Non-specific EKG changes
- Prevention: IVIG + aspirin therapy (an exception to Reye Syndrome)
Kawasaki Disease - Stage 3 (convalescent)
- 1-2 months after initiation of s/s
- Lasts until ESR back to normal
- Most symptoms disappear
- Onychomadesis of toenails - period shedding of proximal end of toinail 2 months after recovery
- Beau lines are deep transverse grooves on nailbed
- Cardiac findings: abnormalities of cardiac vessels, myocarditis
UTI symptoms in neonates (8)
- Jaundice
- Hypothermia
- FTT
- Sepsis
- Vomiting or diarrhea
- Cyanosis
- Abdominal distention
- Lethargy
UTI symptoms in Toddlers & Preschoolers
- malaise, irritability
- difficulty feeding
- Poor weight gain
- Fever
- Vomiting or diarrhea
- Malodor
- Dribbling
- Abdominal pain/colic
UTI symptoms in School-Age children
- Classic dysuria with frequency, urgency and discomfort
- Malodor
- Enuresis
- Abdominal/flank pain
- Fever/chills
- Vomiting or diarrhea
- Malaise
___ is the most common cause of SBI in children < 24 months with fever without a focus
UTI
Complicated UTI s/s
- < 2 yrs
- Upper urinary tract (pylo)
- Hx medical problem
- Abnormal anatomy
- Drug resistant pathogen
- Fever, toxicity, dehydration
UTI Diagnosis on UA
Positive findings on
- Urine luekocyte esterase
- Nitrites
- Leukocyte count, or
- Gram stain
Empiric tx for Pediatric UTI
- Bactrim - 1st line for uncomplicated lower UTI (age > 2 months)
- Amoxicillin/augmentin - for young children with uncomplicated UTI or pyelonephritis
- Cephalexin (age > 6 months)
- Cefixime (age > 6 months)
- Macrobid (age > 1 month)
Duration of tx
- age 2-24 months or febrile: 7-14 days
- age > 24 months and afebrile: 3-5 days can be appropriate
Protocol for child needing renal and bladder u/s
- < 2 y.o with first UTI
- all children with fever + pyelonephritis
- recurrent UTI/
Pediatriac referral to GU
- High-risk - immunocompromised, abnormal u/s
- Age < 3 months = need sepsis workup
- congenital abnormalities
- Pyelonephritis
- Recurrent UTI (about 3 episodes)
UTI risk factors
- > 102.2F
- Females < 1 yr old
- Uncircumcised males
- Duration of fever (> 24-48 hrs)
- Absence of another infection
Low risk for young infant with fever unknown origin
- Well appearing, easily consolable
- previously healthy
- full-term infant (> 37 weeks)
- normal UA (neg Leuko/nitrite), WBC (5-15k), and PCT (>0.3)
- ANC < less than 1,500 bands
- appears well
- no focal bacterial infection; normal CXR
- Reliable caregivers and follow up,
- discharge home and close f/u in 12–24 hours
- no systemic anti w/in 72 hrs
- ANC < 1500 bands
- stool smear negative
- If low-risk criteria not met = be admitted, get LB and CSF studies
- NO empiric antibiotics until LB is obtained to avoid masking or undertreating an undx meningitis
FUO, LB only if have 1 of these:
- WBC count < 5,000 microL or > 15,000 microL (N 5-15k)
- Absolute band count > 1,500 microL (N 2500-6000)
- PCT > 0.5 ng/ml (N < 0.5)
- CRP > 20 mg/L (N 0.8-1)
- Pneumonia on CXR
define fever without origin (FUO)
_>_100.5F at least once daily x 14 days+ and dx not apparent after careful hx, PE, tests
or
>101F+ on several occasions >3 weeks, failure to reach diagnosis, despite 1 week intense investigation
Do you give empiric antibiotics for FUO?
NO!
non painful red eye conditions
conjunctivitis (allergic, viral, bacterial, chemical)
dry eye syndrome
subconjunctival hemorrhage
Viral conjunctivitis key findings
Adenovirus
- redness, itchy, swollen conjunctiva
- tearing, clear watery discharge
- fever, headache, anorexia, malaise
- blepharitis
- pharyngitis with enlarged preauricular nodes
- happens with URI
Adenoviral conjunctivitis management
- Cool compresses
- Lubricating drops
- Good handwashing
- avoid touching the eyes,
- don’t share any towels
- wash pillowcases
- resolves in 1-2 weeks
- NO prophylaxis antibiotics
- Antihistamine ophthalmic for sx relief
With bacterial conjunctivitis (pink eye), consider what in neonate and adolescent and adults sexually active
gonorrhea and chlamydia
Bacteria conjunctivitis key findings
- Erythema 1 or both eyes (uni then bi)
- Yellow - green purulent discharge
- Encrusted and matted eyelid on awakening
- injected conjunctiva
- photophobia
- petechiae on bulbar conjunctiva
- sx’s of URI , otitis media, pharyngitis
- normal vision
bacterial conjunctivitis c/b what orgs
haemophilus influenzae, strep pneumoniae, and staph aureus.
H flu more common in children (dec-april)
Bacterial conjunctivitis: adult management vs children
- Children: empiric (trimethoprim + polymyxin B sulfate ophthalmic soln, erythromycin 0.5% ointment to cover H influ)
- Older children/teens
- WATCH only! Resolves in 1 week no matter what
- Adult: if not immunocompromised → conservatively
- observe or empiric antibiotic x 1 week
- if Chlam/gon = refer CDC
Allergic conjunctivitis results from ____ and is associated with ___
igE mediated hypersensitivity
a/s with atopic disorders, asthma, atopic dermatitis, seasonal, perennial plant
allergic conjunctivitis sx’s and on exam
- bilateral severe eye itching, teary
- rhinitis
- clear, white stringy mucoid discharge
- teary boggy conjunctiva
- allergic shriners/dark circles
allergic conjunctivitis management
Identify/avoid the allergen
Cold compresses and artificial tears
Oral antihistamines if systemic allergy sx’s
- NO antibiotics/steroids
- eye drops:
- Ketotifen (antihistamine)
- Patanol or Olopatadine (prescription); Used > 3 yrs old
how does chemical conjunctivitis occur
Benign: fumes, smoke, chlorine or toxic
- if causes severe pain, vision disturbances = refer!
vernal conjunctivitis
type of allergic conjunctivitis
common in childhood and spring
bilateral
more severe
atopic conjunctivitis
common in >50 yrs old
bilateral itchy, burning, tearing
tx w mass stabilizer eye drop or refer
refer!
dry eye syndrome sx’s
- foreign body sensation
- scratchy gritty feeling stinging, tearing
what test to do for dry eye vs lacrimal problem? Explain.
schirmer test
assesses aqueous production. using filter paper and placing it in the inferior culdesac, measure tear production after 5 mins. < 5 mm = tear deficiency
dry eye management and treatment
Avoid causative medications
anticholinergics or diuretics
Avoid air conditioners or fans
1st line: preservative-free lubricants (OTC) if not work refer and cyclosporin rx
Subconjunctival hemorrhage
- benign
- from increased intrathoracic pressure (coughing sneezing, straining)
- no pain
- common in HTN or blood thinner pts
- resolves in 2 weeks
ocular adnexal disorders
disorders of structures that surround the eye
Blepharitis
Hordeolum (stye)
Chalazion
Nasolacrimal duct obstruction
Preseptal and orbital cellulitis
flakey, yellow scaly debris over eyelid margins on awakening
inflammation of eyelid or follicles
Blepharitis
blepharitis management (3)
- 1st line: warm compresses x 10 mins several times a day
- dilute baby shampoo with warm water and just cleanse the eyelid every day
- Topical antibiotic is only needed if due to a staph infection.
usu resolves with conservative treatment.
If it’s persistent or severe, doxycycline
Define hordeolum (stye) and symptoms
Acute infection and inflammation of eyelid gland d/t to a blocked meibomian gland
Staph aureus
- contact lens use
- painful furuncle/nodules
- NO injection, NO discharge, NO redness
- foreign body sensation
resolves 1-2 weeks (ruptures from compresses or I&D)
Define chalazion and management
Chronic, inflammation of eyelid from lipogranuloma of meibomian
NON painful, non-infectious nodule; results from hordeolum
Warm compresses, gentle massage, weeks to resolve, I&D if persistent
Hordeolum vs Chalazion
chalazion results from a hordeolum
Chalazion: located AWAY from the eyelid margin, more firm, and it’s non-tender, deeper in eyelid
Hordeolum: closer to the eyelid margin
Nasolacrimal duct obstruction (dacryostenosis) symptoms and management
- tearing, mucoid discharge
- blepharitis
- painful, tenderness/swelling over duct
- elevated WBC from exudate
manage:
- Daily massage of the lacrimal duct. If it doesn’t resolve by 12 months = refer for probing procedure.
Complications from dacryostenosis (2)
Dacryocystitis (inflammation of duct = infection)
I&D or systemic antibiotics
Peri/orbital cellulitis
If acute otitis media is associated with conjunctivitis, that’s commonly due to _____ bacteria. So treat with ____
haemophilius influenza
Amoxicillin clavulanate
otitis media risk factors
- allergies
- upper respiratory infection
- cleft palate
- adenoid hypertrophy
- tobacco exposure.
otitis media sx’s
- ear pain
- pulling at ear
- fever (otitis externa has NO fever)
- TM erythema and pain
- worse when child lying down
- otorrhea
mild vs severe otitis media
mild: < 102.2F, sx’s < 48 hrs
severe: >102.fF, sx’s > 48 hrs
otitis media management
Pain control (Tylenol)
Only treat amoxicillin(-clavulanate) or cephalosporin if healthy children (no Down S, cleft palate, tubes):
- severe sx’s > 6 months, medicate then f/u 48-72 hrs of onset of sx’s
- no severe sx’s, < 24 months, bilateral
- if sx’s persist after 48-72 hrs of sx onset
DON’T treat if:
- < 24 months, no severe sx’s, unilateral
- > 24 months, not severe sx’s
Complications of otitis media
- mastoiditis (fever, pain behind ear, swelling posterior ear over mastoid process)
- perforation of TM
- otorrhea
- effusion (fluid; hearing test if > 3 months; refer if > 6 months or hearing lost but watch and wait 48 hrs if mild)
- cholesteatoma (cyst in ear; pearly white lesion = refer!)
the most common cause of infectious pharyngitis
viral
viral pharyngitis management
Tx symptomatic
self-resolve in 5-7 days.
use warm salt water gargles, lozengers, acetaminophen or ibuprofen, and hydration.
Glasgow coma scale score 13-15 means
- mild
- no focal deficits
- < 30 minutes LOC
- may have linear skull fractures
Glasgow coma scale score 9-12 means
- moderate
- focal signs
- variable loss LOC
- may have depressed skull fracture or intracranial hematoma
Glasgow coma scale of < 8 means
- severe
- focal signs
- prolonged loss LOC
- depressed skull fractures and intracranial hematoma
Pedi head injury discharge & education
- If worried caregiver is not reliable = admit
- Discharge home with close observation:
- Minor head trauma and no LOC
- Brief LOC (< 5 mins) with:
- Normal neuro exam
- No s/sx IICP (vomiting, h/a)
- No s/s basilar skull fracture (raccoon eyes, battle sign)
- With or w/o a head CT
- Wake child every 2-4 hours at night for first 24-48 hrs
- Educating parent s/sx of deterioration
- Not responding to q’s
- Vomiting
- Horrible headache
- Slurring speech
highest risk sport for boys and girls for concussion/mild traumatic brain injury?
boys: football and hockey
girls: soccer and basketball
concussion red flags, bring to ED!
- Weakness, numbness, decreased coordination
- Worsening headaches
- Repeated vomiting or nausea
- Slurred speech
- Anisocoria (unequal pupils)
- Seizures
- very drowsy
- Increasing confusion, agitation, restlessness
- Focal neurological signs
- Problem with nerve, spinal cord, left side face numb / arm numb, paralysis of leg
- Can’t recognize people or places
- Neck pain
- Unusual behavior changes
- Any loss of consciousness, especially if for 30 seconds or more
retrograde amnesia vs anterograde amnesia
retrograde amnesia: very brief, can’t recall events before injury
anterograde amnesia: seconds-minutes, can’t make new memories and can’t recall
which imaging preferred for concussions? and what are the indications?
CT scan
indications:
- Focal neurological findings
- Signs of IICP
- GCS < 15 after 2 hrs OR < 13 at any time
- Seizures r/t to trauma
- Age > 60
- Anticoagulation or coagulopathy
- Intoxication
- Recurrent vomiting
- s/sx skull fracture
- LOC (excessive irritability or lethargy)
- LOC >1 min
- Amnesia