Final notes Flashcards
What are the benefits of isothiocyanates in reducing cancer? (there are 5)
- Block cell cycle
- modify phase 1 and phase 2
- induce apoptosis
- modify estrogen metabolism
- indirect antioxidant effect
What are the benefits of resveratrol for CVD?
- anti-inflammatory activity
- increases vasodilation (increases NO synthase) and decreases vasoconstriction (decreases ET 1)
- inhibit smooth muscle cell formation
- inhibit ROS
- inhibit platelet aggregation
What are the benefits of resveratrol on cancer?
- regulation transformation enzymes (phase 1 and phase 2)
- inhibit proliferation of cancer cells and induce apoptosis
- inhibit angiogenesis
- inhibit tumor invasion
- anti-estrogenic or estrogenic
How do isoflavones (phytoestrogens) help reduce the risk of cancers?
- regulates reproductive concentrations
- inhibit angiogenesis
- induce apoptosis
- inhibit DNA topoisomerase
- inhibit tyrosine kinase
- antioxidant effects
Do beta sitosterols have an effect on colon cancer proliferation or prostate cancer proliferation?
Prostate cancer proliferation
how much LDL cholestrol is reduced when we consume 2 grams of plant sterols/days
8.8%
What are the benefits of consuming chocolate on the CVD?
- inhibit LDL oxidation
- inhibit platelet aggregation
- relax smooth muscle
- modulate eicosanoid signaling
Are lignans or isoflavones more abundant in plants?
Lignans
Which phytoestrogen is found in flaxseeds and which one is found in soybenes
Lignans in flaxseeds
Isoflavones is soybeans
How does vitamin C help with Wilson’s disease
Vitamin C helps with Wilsons disease because it will go and impair the absorption of copper, in someone with wilsons disease they absorb more copper than one should.