Final Medications: Wk 8 GI

Question 1

Metoclopramide (reglan) works by blocking ___ receptors in the ___. it is a ___ and enhances movement of ___ ___ contents

Answer 1

dopamine
CTZ
prokinetic
upper GI

Question 2

Metoclopramide (reglan) is used for ____, post- op ___, ___ and ___ therapy

Answer 2

gastoparesis
emesis
chemo
radiation

Question 3

side effects of Metoclopramide (reglan)

Answer 3

high doses cause sedation

EPS > prevelence in kids

Question 4

Metoclopramide (reglan) is contraindicated in ____, h___, or _____

Answer 4

GI obstruction
hemorrhage
perforation

Question 5

Diphenoxylate/Atropine (Lomotil) is often used for ____ ___

Answer 5

travelers

diarrhea

Question 6

Diphenoxylate/Atropine (Lomotil) blocks nerve signals to the ___ muscles, which ___ the muscle and slows ___. Results in decreased painful muscle contraction and prevents___

Answer 6

GI
relaxes
peristalsis
spasm

Question 7

There is potential for drug dependence vs opiates with __. with prolonged use of __ there can be physical dependence

Answer 7

Diphenoxylate/Atropine (Lomotil)

Question 8

Diphenoxylate/Atropine (Lomoti) has ___ effects t/f should not be used in ___ patients, ___, ___, and B__

Answer 8

anticholinergic 
cardiac
tachycardia
glaucoma 
BPH

Question 9

Bisacodyl (Dulcolax)

is a ___ (contact) _____

Answer 9

stimulant

laxative

Question 10

Bisacodyl (Dulcolax) should be avoided in patients with…

Answer 10

intestinal obstruction
severe abdominal pain 
appendicitis 
ulcerative colitis
diverticulitis

Question 11

Prilosec (Omeprazole) is ____ __ used to treat peptic ulcers, ___ and ___ prophylaxis. It can also treat ___ ___ ___which is a hypersecretory disease.

Answer 11

Peptic ulcers
GERD
PUD prophylaxis
Zollinger- Ellison syndrome

Question 12

PPIs suppress gastric secretion by inhibiting the ___ ___ enzyme system in the gastric __ cells. The ___ __ is the last stage in gastric acid secretion, so by inhibition the gastric secretions are suppressed

Answer 12

H+/K+ ATPase
Parietal
Proton pump

Question 13

Side effects of PPIs -> Prilosec (omeprazole)

Answer 13

Headache
Dizziness
Rash
Elevated AST & ALT

Question 14

Adverse effects of Prilosec (omeprazole)

Answer 14

Increased risk for:

• C. Diff
• hip fracture
• anemia
• pneumonia

*can mask gastric cancers

Question 15

Histamine 2 blockers block the h2 receptors of the ___ cells, causing a ___ in ____ ___ and ____. It is used to treatment of ___ and as ___. It can also prevent ___ ___ in the esophagus

Answer 15

Parietal 
Decrease 
Gastric secretion 
Concentration 
PUD 
Prophylaxis 
Acid reflux

Question 16

Ranitidine (zantac) is a __ __ ___. It is potent and has a ___ duration of action. It has ___ side effects then cimetidine (tagament).

Answer 16

Histamine 2 blocker
Long
Fewer

Question 17

Side effects of ranitidine (zantac)

Answer 17

H/a
Nausea 
Vertigo
Diaherrha/ constipation 
Depression 
Blurred vision
Rash
Confusion in older adults

Question 18

Adverse reactions of histamine 2 blockers

Answer 18

Hepatotoxicity
Cardiac dysrhythmias
Blood dyscarias
Can prolong QT interval