Final - Lecture 7

Question 1

How would selection process be modified with multi-birth species?

Answer 1

• select for more traits

- more prone to inbreeding, but can tolerate higher levels

Question 2

How would selection process be modified with single birth species?

Answer 2

• more maternal care
• longer gestation length
• have a more focused opportunity with each individual - don’t have range of phenotype between progeny per generation
• takes longer to accumulate inbreeding (has a bigger impact though)

Question 3

Steps to running a breeding program

Answer 3

1. is ongoing population still viable?
2. do we need to collect more phenotypes?
3. should we alter selection goals?
4. technology to enhance success = EBVs
5. QTL incorporation
6. mating scheme

Question 4

What is too much selection?

Answer 4

• past the point of function

- reduced welfare

Question 5

Who should be in charge of these ethical responsibilities?

Answer 5

• society (consumers)
• breeds (involved in process to move in certain directions)
• Government (to control bans)
• PETA?

Question 6

Who will pay for these ethical responsibilities?

Answer 6

• consumers will speak with money and breeders will be influenced
• society should be more educated

Question 7

What is the role of biotechnology in companion animal genetics?

Answer 7

• cloning
• supply/demand
• human genome as a framework

Question 8

What is the role of phylogeny studies?

Answer 8

• divergence/similarity to other mammals
• process/period/location of domestication
• debunk myths about breed origin
• revise breed designations
• facilitate new breed development

Question 9

What does gene therapy do?

Answer 9

drugs capable of enhancing host/cell/tissue/organ response

Question 10

Pleuripotency

Answer 10

Ability of certain substance capable of producing several distinct biological responses

“jack of all trades, master of none”

Question 11

Pet biotechnology

Answer 11

Location of genes and sequence horology with humans, mice, cattle

Question 12

Genome sequence spin-offs

Answer 12

• phylogeny studies
• gene therapy
• stem cell research
• drug efficacy
• zoonotic diseases
• therapeutics for other species
• designer dogs/cats/birds/horses
• transgenic chimeras

Question 13

Dog breed phylogeny

Answer 13

Arranged in wheel in terms of closeness to domestication of wolf

• develop socioeconomic connections
• looking at number of differences (easy to place - rate of recombination)
• biotechnology - level of domestication