final flex review Flashcards
severity of AKI is determined by what two things/
UO
Cr
2 most common causes for AKI
prerenal
ATN
what is the first indicator of AKI
UO (normal is 0.5mg/kg)
serum Cr takes full day to rise
what are 5 toxic causes of ATN
radiocontrast
aminoglycosides
pigment
cisplatinum
amphotericin B
- interstitial inflammation; renal tubular cell injury
- often hypersensitivity reaction to drugs
- fever, rash, eosinophilia
- NSAIDs can cause tubulointerstitial damage
interstitial nephritis
what 5 drugs can cause interstitial nephritis
abx
furosemide
dilantin
NSAIDs
PPI
RBC casts
glomerular damage–nephritic syndromes
WBC casts
inflammatory conditions
pyelonephritis
AIN
glomerulonephritis
Muddy brown casts
ATN
muddy brown casts
ATN
waxy/granular casts
CKD
epithelial casts
ATN
AIN
nephritic syndrome
doubling of serum Cr every day with hematuria and edema should make you think of
rapidly progressive glomerular nephritis
- over 3.5g protein/day
- low albumin
- elevated lipids
- edema
- non-inflammatory
nephrotic syndrome
- under 3.5g protein/d
- hematuria
- azotemia, oliguria, uremia
- HTN +/- edema
- inflammatory
nephritic syndrome
gold standard to make the dx between nephrotic and nephritic syndrome
kidney biopsy
- viral or parasitic infxn
- acute tubule-interstitial nephropathy
disorders of nephritic syndrome
tx for pyelonephritis
cipro x 14 days or admit for IV cipro
young male w/ dysuria and penile discharge
urethritis
if under 35 test/treat for STI
when do you tx asymptomatic bacteriuria
pregnancy
transplat
prior to TURP
3 tx options for uncomplicated cystitis
TMP-SMX (Bactrim) DS 1 PO BID x 3 days
Nitrofurantoin 100mg PO BID x 5 days
Ciprofloxacin 500mg PO BID x 3 days
complicated cystitis tx (4)
Ciprofloxacin 500mg PO BID x 7 days
TMP-SMZ 1 PO BID x7-10 days
Levofloxacin 750mg PO Q Day x 5 days
Augmentin 500/125mg PO TID x 10-14 days (pregnant)
2 tx options for acute pyelo
Ciprofloxacin 500mg PO BID x 7 days
TMP-SMZ 1 PO BID x14 days
tx for acute prostatitis
Ciprofloxacin 500 mg PO BID x 6 weeks
Levofloxacin 500 mg PO daily x 6 weeks
TMP-SMX one PO BID x 6 weeks
tx GC + chlamydia if sexually active