Final Exam: Treatments Flashcards
Paxlovid: who should use it?
Positive for COVID
12+ years old and 40+ kg
=< 5 days since symptom onset
Have 1+ risk factor for severe illness progression
Paxlovid: what is the dosing?
Two 150 mg tabs nirmatrelvir + one 100 mg tab ritonavir
BID
X 5 days
Molnupiravir: MAINLY beneficial at decreasing what?
Hospitalizations or death from serious illness
Molnupiravir: who SHOULD take?
Positive COVID
Mild-moderate illness
18+ years old
1+ risk of severe illness progression
Molnupiravir: who should NOT take?
X PREGNANT X
Hospitalized patients
Prophylaxis
Longer than 5 days
Molnupiravir: what is the dose?
ONE TIME 200 mg tablet with high fat meal*
Remdesivir: what is the dose?
200 mg IV loading dose
100 mg IV maintenance dose for 5-10 days
Remdesivir: what is the GFR cutoff?
<30
Remdesivir: originally used for what?
Ebola
Remdesivir: hospital or outpatient? Oxygen treatment or no?
Hospital only
Can be used in patients w/ O2 treatment or not
What should ALL COVID patients receive?
Dexamethasone
Corticosteroids: what dose should be used?
Dexamethasone 6 mg IV or PO daily x 10 days or discharge
Tocilizumab: what class of drug is it?
IL-6 antagonist
Tocilizumab: what is the dose?
ONE DOSE 8 mg/kg IV over 1 hour
Tocilizumab: hospital or outpatient? Oxygen treatment or no?
Hospital only
Oxygen treatment (conventional, HFNC or ECMO) patients only