Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Systemic Pharmacology > Final Exam - Study questions > Flashcards

Final Exam - Study questions Flashcards

1
Q

What is the suffix for phosphodisterase ED drugs?

A

-fil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Ocular SE of -FIL drugs

A
  1. Retinal Heme
  2. NAION (non-arteritic ischemic optic neuropathy)
  3. Vision Loss
  4. Elevated IOP
  5. Cyanopsia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which three drugs will inhibit HMG-COA?

a. Alendronate
b. Tamoxifen
c. Statin
d. Sildenafil
e. Methotrexate

A

Alendronate(Osteoprosis), Statin (anti-hyperlipidemic) and FIL (ED drugs)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which two drugs will increase LDL levels?

A

Drospirenone (YAZ - contraception/Acne/Dysmenorrhea/Endometriosis/PCOS)
and
-FIL (phosphodiesterase -ED Drug)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which of the 4 drugs blocks all 3 pathways of the clotting system?

a. Enoxaparin
b. Clopidogrel
c. Coumadin
d. Abciximab

A

Coumadin (Warfarin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which of these drugs is patchy baldness associated with?

a. Enoxaparin
b. Clopidogrel
c. Coumadin
d. Abciximab

A

Coumadin (Warfarin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which of these drugs is Diabetic Retinopathy a contraindication with?

a. Enoxaparin
b. Clopidogrel
c. Coumadin
d. Abciximab

A

Enoxparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which of the following drugs only affects the first two pathways of the clotting system?

a. Enoxaparin
b. Clopidogrel
c. Coumadin
d. Abciximab

A

Enoxaparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the 4 drugs that interact with Coumadin?

A

Tetracycline, Fluoroquinolones, Macrolides and Azole Antifungals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which two of the following drugs will cause Jaundice?

a. Statin
b. Clopidogrel
c. Coumadin
d. Abciximab

A

Clopidogrel and Statin

Note: This is largely due to the fact that this drug is actively metabolized in the Liver, thus liver failure may induce further damage. NIACIN will also cause Jaundice

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which of the following two drugs has fever as an adverse effect?

a. Enoxaparin
b. Clopidogrel
c. Coumadin
d. Abciximab

A

Enoxaparin and Coumadin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which of the following will cause an additive effect on Abciximab/Epitifibatide?

a. Corticosteriods
b. NSAIDs
c. Fluoroquinolones
d. Tetracycliness

A

NSAID’s - Opthalmic inhibit COX and therefore TXA2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are some serious Ocular adverse affects for Statin drugs?

A

Diploplia, Ptosis, pseudo-CME, blurred vision, Increase IOP, intraocular hemorrhage, cataracts (NSC and PSC)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Which two drugs work on the PPAR nuclear level?

a. Statin
b. Niacin
c. Coumadin
d. Zone

A

Statin (hyperlipidemic and Zone drugs (DM drug)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which of the following drug will cause CME and toxic amblyopia?

a. Statin
b. Niacin
c. Coumadin
d. Zone

A

Niacin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Which drug can be used for DM 1 and 2?

A

Insulin Glargine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Which of the following anti lipid drugs will impair renal elimination when interacted with Gancyciclovir?

a. Statin
b. Fibrate
c. Niacin

A

Fibrate

Note: Gancyclovir interacting with Stiagliptin will also cause renal failure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Which of the following drugs will display a decrease in metabolism of Metformin, when interacted?

a. Amphotericin
b. Aminoglycosides
c. Acyclovir
d. Cyclosporine

A

Cyclosporine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Which of the following drugs, does not have a similar drug interaction to the rest?

a. Glipizide
b. Piolitazone
c. Sitaliptin
d. Metformin

A

Metformin

Note: Fish oils = increase blood sugar
Cyclosporine = decrease metabolism
Aminoglycoside, Amphotericin, Ganciclovir, Acyclovir = Nephro-toxicity lactic acidosis
Flaxseed = decreased blood sugar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Which of the following drugs will cause a metallic taste as an adverse effect?

a. Glipizide
b. Piolitazone
c. Sitaliptin
d. Metformin

A

Metformin

Note: Rash, Lactic Acidosis and Megaloblastic anemia is unique to this drug

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Which of the following drugs may cause photosensitivity but also cause death, as an adverse reaction?

a. Glipizide
b. Piolitazone
c. Sitaliptin
d. Metformin

A

Glipizide

Note: Causes Cardiovascular death

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Which drug will have a prolonged effect due to NSAID’s?

a. Glipizide
b. Pioglitazone
c. Sitaliptin
d. Metformin

A

Glipizide

Note: Class is a sulfonurea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Which drug will possibly give you flu like symptoms?

a. Statin
b. Fibrate
c. Niacin

A

Fibrate

Note: Fibrate also has muscular side effects as well

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Which of the following is has an adverse effect and causes Diabetic Macular edema and Bladder Cancer?

a. Glipizide
b. Pioglitazone
c. Sitaliptin
d. Metformin

A

Pioglitazone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Which two drugs will impair metabolism of Zone drugs?

a. Acyclovir
b. Azoles
c. Beta Blockers
d. Trimethoprim
e. Flaxseed Oil

A

Azoles and Trimethoprim

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Which of the following drugs should you NOT use when an ocular disease is present?

a. Enoxaparin
b. Clopidogrel
c. Coumadin
d. Abciximab

A

Clopidogrel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Which of the following drugs should not be given to an individual with high cholestrol readings?

a. Enoxaparin
b. Clopidogrel
c. Coumadin
d. Abciximab

A

Coumadin

Note: May cause cholesterol embolism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Which of the following drugs can be used for a bacterial infection (H. Pylori) in the eye?

a. Estrone
b. Tamoxifen
c. Coumadin
d. Esomeprazole

A

Esomeprazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Which of the following drug causes dry mouth and diarrhea?

a. Estrone
b. Tamoxifen
c. Cimetidine
d. Esomeprazole

A

Cimetidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Which of the following drugs will cause gynecomastia?

a. Cimetidine
b. Tamoxifen
c. Coumadin
d. Esomeprazole

A

Cimetidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Which of the following drugs does not have any adverse affects?

a. Estrone
b. Tamoxifen
c. Coumadin
d. Esomeprazole

A

Esomeprazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Which of the following drugs causes Pseudotumor cerebri as an adverse reaction?

a. Estrone
b. Levothyroxine
c. Tamoxifen
d. Esomeprazole

A

Levothyroxine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

Which of the followings has an additive affect on Thyroid therapies?

a. B-blockers
b. Alpha Agonist
c. Sympathomimetics
d. NSAID’s

A

Sympathomimetics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

Which of the following drugs impairs the metabolism of caffeine?

a. Cimetidine
b. Tamoxifen
c. Coumadin
d. Esomeprazole

A

Cimetidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Which of the following drugs is an indication for Choriocarcinoma?

a. Cimetidine
b. Tamoxifen
c. Promethazine
d. Methotrexate

A

Methotrexate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

Which of the following is not an adverse affect of Alendronate?

a. Photosensitivity
b. Uveitis
c. Conjunctivitis
d. Scleritis

A

Conjunctivitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

Which of the following has big issue of producing too much production of vitamin k clotting factor?

a. Levothyroxine
b. Estrone
c. Drospirenone
d. Tamoxifen

A

Estrone

38
Q

Which of the three are ocular adverse affects of Thyroid drug.

a. Ptosis
b. Diplopia
c. EOM paresis
d. Ocular lesions
e. Contact lens

A

Ptosis, Diplopia and EOM

39
Q

Which of the following drugs, pick 2, causes an intolerance to Contact lenses?

a. Estrone
b. Estradiol
c. Tamoxifen
d. Clomiphene

A

Estrone and Estradiol

40
Q

Which hormone will induce a further affect of endometrial cancer and invasive breast cancer?

a. Estrone
b. Estradiol
c. Tamoxifen
d. Coumadin

A

Estrone

Note: DVT and MI are also part of this black box warning

41
Q

What type of phasic drug is YAZ?

a. monophasic
b. diphasic
c. triphasic
d. four phasic

A

monophasic

42
Q

Which type of vitamin will decrease the metabolism of YAZ?

a. Vit A
b. Vit B
c. Vit C
d. Vit D

A

Vit C = Ascorbic Acid

43
Q

Which of the following is an additive to hyperkalemia for contraception drugs?

a. Steroids
b. Tetracycline
c. Fluoroquinolones
d. NSAID’s

A

NSAID’s

44
Q

Severe adverse affects of Tamoxifen?

a. Stroke
b. Pancytopenia
c. Cataracts
d. Thromboembolism
e. Retinopathy
f. All of the above

A

All of the above

45
Q

Which of the following drugs will increase the levels of Cyclosporine, Steroids and Oxycodone?

a. Tamoxifen
b. Estradiol
c. Esterone
d. Yaz

A

Tamoxifen

46
Q

Which of the following two will decrease the effectiveness of Tamoxifen?

a. Fluoroquinolines
b. Statin drugs
c. Macrolides
d. Chlorpheiramine

A

Macrolide and Chlorpheiramine

47
Q

What type of affect will occur when NSAIDs and Methotrexate are combined?

a. Increase the affect of both
b. Decrease their affect
c. Allergy reaction
d. Myelosuppression

A

Fatal myelosuppression

48
Q

True or False. Bone marrow density will decrease as you take Methotrexate.

A

True

49
Q

Which of the following will cause neurotoxcity

a. Pemetrexed
b. Methotrexate
c. Trimethoprim
d. Pyrimethamine

A

All of these. They are all anti metabolites

50
Q

What would you take with central antiviral agents to lower the pH content?

a. Milk
b. Water
c. Coca Cola
d. Cocaine

A

Coca Cola - it will lower the pH level considerably faster

51
Q

At which level of the H2 receptor will only be affective?

a. Alpha level
b. Beta level
c. Kappa level
d. Basal Level

A

Basal level

52
Q

Match the following with hyperthyroidism and hypothyroidism.

a. Bradycardia
b. Tachycardia

A 
Hyper = Tachy
Hypo = Brady
53
Q

True or False. Estrogen dosing for menopause is significantly higher and safer than contraception.

A

False. Estrogen does for menopause is LOWER and safer than contraception

54
Q

What is the most potent estrogen producer?

A

Estradiol

Note: Estrone is a metabolite of Estradiol and will be 1/3 potent as Estradiol

55
Q

Which gender does osteoporosis occur in the most?

A

Female

Note: Cholesterol build up

56
Q

What are the two most lethal cancer’s that can spread to the eye?

A

Lung and Breast

57
Q

What are the top 4 cancer deaths in males?

A
  1. Lung 2. Prostate 3. Colon 4. Pancreas
58
Q

What are the top 4 cancer deaths in females?

A
  1. Lung 2. Breast 3. Colon 4. Pancreas
59
Q

What are the highest amount of new cases in males?

A

Prostate

60
Q

What are the highest amount of new cases in females?

A

Breast

61
Q

Which type of drug also has the similar affects as chemotherapy of vomitting, nausea and chemical structure of the drug?

A

Anti-psychotics

62
Q

Which is correct?

a. Arterial thrombosis = Coagulation Cascade
b. Arterial thrombosis = Platlet rich clot

A

b. Arterial thrombosis = Platlet rich clot

63
Q

Which is correct?

a. Venous thrombosis = Coagulation Cascade
b. Venous thrombosis = Platlet rich clot

A

Venous thrombosis = Coagulation Cascade

64
Q

Which of the two pathways, Extrinsic or Intrinsic, causes a thrombin burst?

A

Extrinsic - synthesis of vitamin K coagulation factors

65
Q

Which of the two pathways, Extrinsic or Intrinsic, is important in the inflammatory pathway?

A

Intrinsic

66
Q

What of the following is a contraindication for a statin drug?

a. Apple juice
b. Orange Juice
c. Grapefruit juice
d. Purple Drank

A

Grapefruit juice

67
Q

True or False. Coronary heart disease causes 1/2 deaths in all of the US

A

True

68
Q

True or False. Type 2 DM is most common in Overweight, Non-caucasian and Over 40 years of age.

A

True

69
Q

Which ethnic group has the greatest risk for insulin resistance?

A

Latino’s

70
Q

Which ethnic group has the greatest for Beta cell dysfunction?

A

East Asian

71
Q

What is the most common side effect from Anti HTN?

A

Headache

72
Q

Which structure is the most similar to Morphine?

a. Hydrocodon
b. Codeine
c. Heroine
d. NSAID’s

A

Codeine

Note: NSAID’s are the most different

73
Q

What is the most common side affect of Lisinopril?

A

Cough with plegm

74
Q

Lisinopril is associated with what ocular side effects?

A

Ocular surface issues, Dry eye (when combined with BBlockers)

75
Q

Amlodipine is associated with what ocular issues?

A

Diplopia, Pain, and Conjunctivitis (when combined with Lisinopril)

76
Q

Terazosin is associated with what ocular side effects?

A

Catract surgery and Intraoperative floppy iris syndrome and Pain

77
Q

Metaprolol/Atenolol is associated with what ocular issues?

A

Decrease IOP, Glaucoma progression, Opth Decong anatagonist

78
Q

Furosemide is inhibits reabsorption of NaCl at what parts of the kidney?

A

Proximal and Distal

79
Q

What drugs are hypersensitive to Sulfonamides?

A

Furosemide, HCTZ diuretic

80
Q

What major ocular issue is associated with HCTZ diuretic?

A

Angle Closeure Glaucoma

81
Q

Which drug is associated with Lupus Erythematosus?

A

Hydralazine

82
Q

Escitalopram is associated with what ocular issues?

A

Ptosis, Conjunctivitis, Diplopia, Blur and DRY EYE!

83
Q

Which of the following is not an SSRI?

a. Fluoxetine
b. Duloxetine
c. Escitalopram
d. Sertraline

A

Duloxetine

84
Q

Which typical anti-pshycotic drug is associated with cataracts?

A

Qutiapine

85
Q

Which alzheimer drug inactivates ACHesterases?

A

Donepizil

86
Q

Which drug is associated with Parkinsons?

A

Sinemet

87
Q

Celecoxib has 4 major side effects. Name them.

A

Bleeding, Ulcer, Stroke and Sulfa allergy

88
Q

Which drug is associated with respiratory disease, that also has a side-effect causing conjunctivitis

A

Tramadol

89
Q

What are the 3 ocular side effects of Fluticasone?

A

Cataracts, Glaucoma and Increase IOP

90
Q

Name the 5 ocular issues related to Mometasone.

A

Increase IOP, Glaucoma, HSV infection, Cataracts and Vision changes

Systemic Pharmacology (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions