Final Exam - Study questions Flashcards
What is the suffix for phosphodisterase ED drugs?
-fil
Ocular SE of -FIL drugs
- Retinal Heme
- NAION (non-arteritic ischemic optic neuropathy)
- Vision Loss
- Elevated IOP
- Cyanopsia
Which three drugs will inhibit HMG-COA?
a. Alendronate
b. Tamoxifen
c. Statin
d. Sildenafil
e. Methotrexate
Alendronate(Osteoprosis), Statin (anti-hyperlipidemic) and FIL (ED drugs)
Which two drugs will increase LDL levels?
Drospirenone (YAZ - contraception/Acne/Dysmenorrhea/Endometriosis/PCOS)
and
-FIL (phosphodiesterase -ED Drug)
Which of the 4 drugs blocks all 3 pathways of the clotting system?
a. Enoxaparin
b. Clopidogrel
c. Coumadin
d. Abciximab
Coumadin (Warfarin)
Which of these drugs is patchy baldness associated with?
a. Enoxaparin
b. Clopidogrel
c. Coumadin
d. Abciximab
Coumadin (Warfarin)
Which of these drugs is Diabetic Retinopathy a contraindication with?
a. Enoxaparin
b. Clopidogrel
c. Coumadin
d. Abciximab
Enoxparin
Which of the following drugs only affects the first two pathways of the clotting system?
a. Enoxaparin
b. Clopidogrel
c. Coumadin
d. Abciximab
Enoxaparin
What are the 4 drugs that interact with Coumadin?
Tetracycline, Fluoroquinolones, Macrolides and Azole Antifungals
Which two of the following drugs will cause Jaundice?
a. Statin
b. Clopidogrel
c. Coumadin
d. Abciximab
Clopidogrel and Statin
Note: This is largely due to the fact that this drug is actively metabolized in the Liver, thus liver failure may induce further damage. NIACIN will also cause Jaundice
Which of the following two drugs has fever as an adverse effect?
a. Enoxaparin
b. Clopidogrel
c. Coumadin
d. Abciximab
Enoxaparin and Coumadin
Which of the following will cause an additive effect on Abciximab/Epitifibatide?
a. Corticosteriods
b. NSAIDs
c. Fluoroquinolones
d. Tetracycliness
NSAID’s - Opthalmic inhibit COX and therefore TXA2
What are some serious Ocular adverse affects for Statin drugs?
Diploplia, Ptosis, pseudo-CME, blurred vision, Increase IOP, intraocular hemorrhage, cataracts (NSC and PSC)
Which two drugs work on the PPAR nuclear level?
a. Statin
b. Niacin
c. Coumadin
d. Zone
Statin (hyperlipidemic and Zone drugs (DM drug)
Which of the following drug will cause CME and toxic amblyopia?
a. Statin
b. Niacin
c. Coumadin
d. Zone
Niacin
Which drug can be used for DM 1 and 2?
Insulin Glargine
Which of the following anti lipid drugs will impair renal elimination when interacted with Gancyciclovir?
a. Statin
b. Fibrate
c. Niacin
Fibrate
Note: Gancyclovir interacting with Stiagliptin will also cause renal failure
Which of the following drugs will display a decrease in metabolism of Metformin, when interacted?
a. Amphotericin
b. Aminoglycosides
c. Acyclovir
d. Cyclosporine
Cyclosporine
Which of the following drugs, does not have a similar drug interaction to the rest?
a. Glipizide
b. Piolitazone
c. Sitaliptin
d. Metformin
Metformin
Note: Fish oils = increase blood sugar
Cyclosporine = decrease metabolism
Aminoglycoside, Amphotericin, Ganciclovir, Acyclovir = Nephro-toxicity lactic acidosis
Flaxseed = decreased blood sugar
Which of the following drugs will cause a metallic taste as an adverse effect?
a. Glipizide
b. Piolitazone
c. Sitaliptin
d. Metformin
Metformin
Note: Rash, Lactic Acidosis and Megaloblastic anemia is unique to this drug
Which of the following drugs may cause photosensitivity but also cause death, as an adverse reaction?
a. Glipizide
b. Piolitazone
c. Sitaliptin
d. Metformin
Glipizide
Note: Causes Cardiovascular death
Which drug will have a prolonged effect due to NSAID’s?
a. Glipizide
b. Pioglitazone
c. Sitaliptin
d. Metformin
Glipizide
Note: Class is a sulfonurea
Which drug will possibly give you flu like symptoms?
a. Statin
b. Fibrate
c. Niacin
Fibrate
Note: Fibrate also has muscular side effects as well
Which of the following is has an adverse effect and causes Diabetic Macular edema and Bladder Cancer?
a. Glipizide
b. Pioglitazone
c. Sitaliptin
d. Metformin
Pioglitazone
Which two drugs will impair metabolism of Zone drugs?
a. Acyclovir
b. Azoles
c. Beta Blockers
d. Trimethoprim
e. Flaxseed Oil
Azoles and Trimethoprim
Which of the following drugs should you NOT use when an ocular disease is present?
a. Enoxaparin
b. Clopidogrel
c. Coumadin
d. Abciximab
Clopidogrel
Which of the following drugs should not be given to an individual with high cholestrol readings?
a. Enoxaparin
b. Clopidogrel
c. Coumadin
d. Abciximab
Coumadin
Note: May cause cholesterol embolism
Which of the following drugs can be used for a bacterial infection (H. Pylori) in the eye?
a. Estrone
b. Tamoxifen
c. Coumadin
d. Esomeprazole
Esomeprazole
Which of the following drug causes dry mouth and diarrhea?
a. Estrone
b. Tamoxifen
c. Cimetidine
d. Esomeprazole
Cimetidine
Which of the following drugs will cause gynecomastia?
a. Cimetidine
b. Tamoxifen
c. Coumadin
d. Esomeprazole
Cimetidine
Which of the following drugs does not have any adverse affects?
a. Estrone
b. Tamoxifen
c. Coumadin
d. Esomeprazole
Esomeprazole
Which of the following drugs causes Pseudotumor cerebri as an adverse reaction?
a. Estrone
b. Levothyroxine
c. Tamoxifen
d. Esomeprazole
Levothyroxine
Which of the followings has an additive affect on Thyroid therapies?
a. B-blockers
b. Alpha Agonist
c. Sympathomimetics
d. NSAID’s
Sympathomimetics
Which of the following drugs impairs the metabolism of caffeine?
a. Cimetidine
b. Tamoxifen
c. Coumadin
d. Esomeprazole
Cimetidine
Which of the following drugs is an indication for Choriocarcinoma?
a. Cimetidine
b. Tamoxifen
c. Promethazine
d. Methotrexate
Methotrexate
Which of the following is not an adverse affect of Alendronate?
a. Photosensitivity
b. Uveitis
c. Conjunctivitis
d. Scleritis
Conjunctivitis
Which of the following has big issue of producing too much production of vitamin k clotting factor?
a. Levothyroxine
b. Estrone
c. Drospirenone
d. Tamoxifen
Estrone
Which of the three are ocular adverse affects of Thyroid drug.
a. Ptosis
b. Diplopia
c. EOM paresis
d. Ocular lesions
e. Contact lens
Ptosis, Diplopia and EOM
Which of the following drugs, pick 2, causes an intolerance to Contact lenses?
a. Estrone
b. Estradiol
c. Tamoxifen
d. Clomiphene
Estrone and Estradiol
Which hormone will induce a further affect of endometrial cancer and invasive breast cancer?
a. Estrone
b. Estradiol
c. Tamoxifen
d. Coumadin
Estrone
Note: DVT and MI are also part of this black box warning
What type of phasic drug is YAZ?
a. monophasic
b. diphasic
c. triphasic
d. four phasic
monophasic
Which type of vitamin will decrease the metabolism of YAZ?
a. Vit A
b. Vit B
c. Vit C
d. Vit D
Vit C = Ascorbic Acid
Which of the following is an additive to hyperkalemia for contraception drugs?
a. Steroids
b. Tetracycline
c. Fluoroquinolones
d. NSAID’s
NSAID’s
Severe adverse affects of Tamoxifen?
a. Stroke
b. Pancytopenia
c. Cataracts
d. Thromboembolism
e. Retinopathy
f. All of the above
All of the above
Which of the following drugs will increase the levels of Cyclosporine, Steroids and Oxycodone?
a. Tamoxifen
b. Estradiol
c. Esterone
d. Yaz
Tamoxifen
Which of the following two will decrease the effectiveness of Tamoxifen?
a. Fluoroquinolines
b. Statin drugs
c. Macrolides
d. Chlorpheiramine
Macrolide and Chlorpheiramine
What type of affect will occur when NSAIDs and Methotrexate are combined?
a. Increase the affect of both
b. Decrease their affect
c. Allergy reaction
d. Myelosuppression
Fatal myelosuppression
True or False. Bone marrow density will decrease as you take Methotrexate.
True
Which of the following will cause neurotoxcity
a. Pemetrexed
b. Methotrexate
c. Trimethoprim
d. Pyrimethamine
All of these. They are all anti metabolites
What would you take with central antiviral agents to lower the pH content?
a. Milk
b. Water
c. Coca Cola
d. Cocaine
Coca Cola - it will lower the pH level considerably faster
At which level of the H2 receptor will only be affective?
a. Alpha level
b. Beta level
c. Kappa level
d. Basal Level
Basal level
Match the following with hyperthyroidism and hypothyroidism.
a. Bradycardia
b. Tachycardia
Hyper = Tachy Hypo = Brady
True or False. Estrogen dosing for menopause is significantly higher and safer than contraception.
False. Estrogen does for menopause is LOWER and safer than contraception
What is the most potent estrogen producer?
Estradiol
Note: Estrone is a metabolite of Estradiol and will be 1/3 potent as Estradiol
Which gender does osteoporosis occur in the most?
Female
Note: Cholesterol build up
What are the two most lethal cancer’s that can spread to the eye?
Lung and Breast
What are the top 4 cancer deaths in males?
- Lung 2. Prostate 3. Colon 4. Pancreas
What are the top 4 cancer deaths in females?
- Lung 2. Breast 3. Colon 4. Pancreas
What are the highest amount of new cases in males?
Prostate
What are the highest amount of new cases in females?
Breast
Which type of drug also has the similar affects as chemotherapy of vomitting, nausea and chemical structure of the drug?
Anti-psychotics
Which is correct?
a. Arterial thrombosis = Coagulation Cascade
b. Arterial thrombosis = Platlet rich clot
b. Arterial thrombosis = Platlet rich clot
Which is correct?
a. Venous thrombosis = Coagulation Cascade
b. Venous thrombosis = Platlet rich clot
Venous thrombosis = Coagulation Cascade
Which of the two pathways, Extrinsic or Intrinsic, causes a thrombin burst?
Extrinsic - synthesis of vitamin K coagulation factors
Which of the two pathways, Extrinsic or Intrinsic, is important in the inflammatory pathway?
Intrinsic
What of the following is a contraindication for a statin drug?
a. Apple juice
b. Orange Juice
c. Grapefruit juice
d. Purple Drank
Grapefruit juice
True or False. Coronary heart disease causes 1/2 deaths in all of the US
True
True or False. Type 2 DM is most common in Overweight, Non-caucasian and Over 40 years of age.
True
Which ethnic group has the greatest risk for insulin resistance?
Latino’s
Which ethnic group has the greatest for Beta cell dysfunction?
East Asian
What is the most common side effect from Anti HTN?
Headache
Which structure is the most similar to Morphine?
a. Hydrocodon
b. Codeine
c. Heroine
d. NSAID’s
Codeine
Note: NSAID’s are the most different
What is the most common side affect of Lisinopril?
Cough with plegm
Lisinopril is associated with what ocular side effects?
Ocular surface issues, Dry eye (when combined with BBlockers)
Amlodipine is associated with what ocular issues?
Diplopia, Pain, and Conjunctivitis (when combined with Lisinopril)
Terazosin is associated with what ocular side effects?
Catract surgery and Intraoperative floppy iris syndrome and Pain
Metaprolol/Atenolol is associated with what ocular issues?
Decrease IOP, Glaucoma progression, Opth Decong anatagonist
Furosemide is inhibits reabsorption of NaCl at what parts of the kidney?
Proximal and Distal
What drugs are hypersensitive to Sulfonamides?
Furosemide, HCTZ diuretic
What major ocular issue is associated with HCTZ diuretic?
Angle Closeure Glaucoma
Which drug is associated with Lupus Erythematosus?
Hydralazine
Escitalopram is associated with what ocular issues?
Ptosis, Conjunctivitis, Diplopia, Blur and DRY EYE!
Which of the following is not an SSRI?
a. Fluoxetine
b. Duloxetine
c. Escitalopram
d. Sertraline
Duloxetine
Which typical anti-pshycotic drug is associated with cataracts?
Qutiapine
Which alzheimer drug inactivates ACHesterases?
Donepizil
Which drug is associated with Parkinsons?
Sinemet
Celecoxib has 4 major side effects. Name them.
Bleeding, Ulcer, Stroke and Sulfa allergy
Which drug is associated with respiratory disease, that also has a side-effect causing conjunctivitis
Tramadol
What are the 3 ocular side effects of Fluticasone?
Cataracts, Glaucoma and Increase IOP
Name the 5 ocular issues related to Mometasone.
Increase IOP, Glaucoma, HSV infection, Cataracts and Vision changes
