Final Exam - Pseudomonas to Rickettsia Flashcards
Describe the morphology of Pseudomonas
Gram negative rods, obligate aerobe (cat +/ Oxid -), motile rods, ubiquitous
what exotoxins does P. Aeuriginosa have? WHAT DO THEY DO?
T3SS,
Exotoxin A - inhibits prot synthesis
Exotoxin S & T - interferes with phagocytosis by affecting the actin cytoskeleton
Exotoxin U - cytotoxic effect
Exotoxin Y - increases intracellular CAMP to cytopathic levels
What bacteria causes kennel cough?
Bordetella bronchiseptica
What causes turkey coryza?
Bordetella avium
tracheobronchitis, sinusisits, conjunctivitis
What causes rabbit syphillis?
treponema paraluiscuniculi
What causes fowl Spirochetosis?
Borrelia answerina (chickens - greenish diarrhia)
Tularemia is caused by what?
Francissella tularensis
Tularemia is spread by what vector?
dermacenter and ambylomma
Tularemia is also known as what?
rabbit fever, deer fly fever, lemming fever?
Is Tularemia reportable?
Yes
Is lyme disease reportable?
only in humans, not in animals
Name the vector for lyme disease
ixodes scapularis, ixodes pacificus
Name the vector for Borellia Burgdorferi sensu loto
ixodes scapularis, ixodes pacificus (deer tick and western black leg tick), 2 year ticks!
What is Ixodes a vector for?
borellia burdorferi – lyme disease
Is chlamydia psittici reportable?
Yes
What bacteria causes infectious canine tracheobronchitis
Bordetella bronchiseptica
What organisms from Murphy’s review cause abortion?
brucella, campylobacter and chlamydia (and Rickettsia)
Does taylorella cause abortions?
No, but it does cause a failure to conceive
Reproductive and GI problems are associated with what genus of bacteria?
Camplylobacter
What two bacteria have cytolethal distending toxin?
helicobacter and campylobacter
What’s special about chlamydia?
Two phases – elementary body and reticulate body
What is the infective form of chlamydia? Is it metabolically active?
elementary body, metabolically inactive
How does chlamydia infect other cells once inside a host cell?
inside a cell it becomes metabolically active reticulate body, makes more elementary bodies to be released from host cell and infect other cells
What are important pathogen characteristics of helicobacter?
cytolethal distending toxin, lives in stomach, produces urease to make ammonia and neutralize stomach acid
A dog comes into your clinic with a nasty skin/ear infection. On a gram stain you see WBC’s and G- cocci. What org comes to mind?
staphylococcus
A dog comes into your clinic with a nasty skin/ear infection. On a gram stain you see WBC’s and G+ cocci. What org comes to mind?
streptococcus
A dog comes into your clinic with a nasty skin/ear infection. On a gram stain you see WBC’s and G- rods. What orgs come to mind?
pseudomonas, e. coli
What causes Glanders?
Burkholderia mallei
What causes pseudoglanders?
Burkholderia pseudomallei
What causes myleidosis
Burkholderia pseudomallei
What causes Farcy?
Burkholderia mallei (cutaneous glanders)
What causes Contagious Equine Metritis?
Taylorella equigenitalis
What causes recurrent uveitis in horses?
leptospira interrogans
What is the model organism for eye issues in cattle?
moraxella
When Moraxella causes an infection in an eye what is it called?
Infectious Bovine Keratosis (IBK)
mycoplasma felis infects what species?
cats and horses
What causes human syphillis?
treponema pallidum
What species of chlamydia is reportable?
chlasmydia psittici
What species of chlamydia are zoonotic?
c. abortus, c. felis, c. pneumonia, c. psittici
what’s the only hemotrophic mycoplasma we learned?
myocplasma haemophilus – all others are NON hemotrophic
mycoplasma haemophilus causes hemolytic anemia in what species?
cats
What is a clinical sign of swine dysentery?
bloody diarrhea
What causes porcine proliferative enteritis?
Lawsonia intracellularis
What is a clinical sign of porcine proliferative enteritis?
non-bloody diarrhea (‘garden hose’ duct)
True or false: dermonecrotic toxin is produced by pasteurella?
false. produced by bordetella
What are the five toxins of bordetella? What do they do?
1) Trachael cytotoxin - damages ciliated epithelial cell
2) dermonectrotic toxin - affects actin cytoskeleton, inhibits osteoblasts (atrophic rhinitis)
3) adenyl cyclase toxin - pore forming, rereg. ion and fluid flow, hemolytic, reduces phagocytic capacity of leukocytes
4) pertussis toxin (B. pertussis only) - loss of fluids and ions, inhibits phagocytes
5) osteotoxin - lethal to trachael and bone cells
Where does brucella multiply in cells?
inside macrophages
Is brucella reportable?
yes
Is brucella zoonotic?
yes
Does brucella cause abortion?
Yes, in cows, people, swine and dogs
Is Brucella a problem in the US?
Yes because of wild pigs and animals (deer)
T/F: Both Lawsonia and Chladmydia are intracellular?
TRUE
Name reportable diseases (There are ____)
Burkholderia mallei
What color is pseudomonas on MacConkey Agar?
colorless
What causes pseudomonas to appear lime green?
blue pyocyanin (virulence factor) and yellow fleuroscin
How can you distinguish Burkholderia pseudomallei from mallei?
pseudo is motile (and grows on cepacia agar?)
pseudo causes meliodosis and pseudoglanders
how can you distinguish melioidosis from glanders?
glanders – horses and cats mainly
meliodosis mainly sheep and goats
glanders - B mallei (non motile)
meliodosis - B pseudomallei (motile)
What causes whitemore’s dz in humans?
Burkholderia pseuodmallei “vietnamese time bomb”
What causes CEM contagious equine metritis?
Taylorella equigenitalis
What causes swine dysentery?
Brachyspira hyodysenteriae (growing pigs 6-12 weeks)
Swine dysentery affects what age group of swine?
growing pigs, 6-12 weeks
What causes proliferative enteropathy in pigs, horses, mammals and birds?
lawsonia intracellularis
the leading cause of food-borne bacterial gastroenteritis in humans
C jejuni and C coli
necrotic donut hole shaped lesions are pathognomonis for what?
ovine camplylobacter: c. jejuni or c. fetus ssp fetus
What is found in 50% of the ceca of chickens?
Campylobacter jejuni
how can you distinguish campylobacter from acrobacter?
campylobacter will not grow below 30 degrees C but arco will
What causes “weak calf syndrome”
leptospira ser. hardio
What is the tick vector for borellia anserina?
argas persicus (soft tick)
what causes infectious sinusitis in turkeys?
mycoplasma gallisepticum
what causes sternal bursitis in turkeys?
mycoplasma synovial
what causes contagious bovine pleuropneumonia (CBPP)
mycoplasma mycoides ssp mycoides SMALL COLONY
True or false: mycoplasma are normal commensal organisms of the lower urogenital tract?
true – dz usually in overcrowded/stressed animals
What does mycoplasma mycoides ssp mycoides LARGE colony cause?
mastitits, pneumonia, septicemia in kids