Final Exam - Pseudomonas to Rickettsia Flashcards by Elizabeth Noelle

Describe the morphology of Pseudomonas

Gram negative rods, obligate aerobe (cat +/ Oxid -), motile rods, ubiquitous

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what exotoxins does P. Aeuriginosa have? WHAT DO THEY DO?

T3SS,
Exotoxin A - inhibits prot synthesis
Exotoxin S & T - interferes with phagocytosis by affecting the actin cytoskeleton
Exotoxin U - cytotoxic effect
Exotoxin Y - increases intracellular CAMP to cytopathic levels

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What bacteria causes kennel cough?

Bordetella bronchiseptica

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What causes turkey coryza?

Bordetella avium

tracheobronchitis, sinusisits, conjunctivitis

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What causes rabbit syphillis?

treponema paraluiscuniculi

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What causes fowl Spirochetosis?

Borrelia answerina (chickens - greenish diarrhia)

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Tularemia is caused by what?

Francissella tularensis

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Tularemia is spread by what vector?

dermacenter and ambylomma

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Tularemia is also known as what?

rabbit fever, deer fly fever, lemming fever?

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Is Tularemia reportable?

Yes

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Is lyme disease reportable?

only in humans, not in animals

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Name the vector for lyme disease

ixodes scapularis, ixodes pacificus

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Name the vector for Borellia Burgdorferi sensu loto

ixodes scapularis, ixodes pacificus (deer tick and western black leg tick), 2 year ticks!

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What is Ixodes a vector for?

borellia burdorferi – lyme disease

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Is chlamydia psittici reportable?

Yes

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What bacteria causes infectious canine tracheobronchitis

Bordetella bronchiseptica

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What organisms from Murphy’s review cause abortion?

brucella, campylobacter and chlamydia (and Rickettsia)

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Does taylorella cause abortions?

No, but it does cause a failure to conceive

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Reproductive and GI problems are associated with what genus of bacteria?

Camplylobacter

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What two bacteria have cytolethal distending toxin?

helicobacter and campylobacter

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What’s special about chlamydia?

Two phases – elementary body and reticulate body

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What is the infective form of chlamydia? Is it metabolically active?

elementary body, metabolically inactive

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How does chlamydia infect other cells once inside a host cell?

inside a cell it becomes metabolically active reticulate body, makes more elementary bodies to be released from host cell and infect other cells

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What are important pathogen characteristics of helicobacter?

cytolethal distending toxin, lives in stomach, produces urease to make ammonia and neutralize stomach acid

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A dog comes into your clinic with a nasty skin/ear infection. On a gram stain you see WBC's and G- cocci. What org comes to mind?

staphylococcus

A dog comes into your clinic with a nasty skin/ear infection. On a gram stain you see WBC's and G+ cocci. What org comes to mind?

streptococcus

A dog comes into your clinic with a nasty skin/ear infection. On a gram stain you see WBC's and G- rods. What orgs come to mind?

pseudomonas, e. coli

What causes Glanders?

Burkholderia mallei

What causes pseudoglanders?

Burkholderia pseudomallei

What causes myleidosis

Burkholderia pseudomallei

What causes Farcy?

Burkholderia mallei (cutaneous glanders)

What causes Contagious Equine Metritis?

Taylorella equigenitalis

What causes recurrent uveitis in horses?

leptospira interrogans

What is the model organism for eye issues in cattle?

moraxella

When Moraxella causes an infection in an eye what is it called?

Infectious Bovine Keratosis (IBK)

mycoplasma felis infects what species?

cats and horses

What causes human syphillis?

treponema pallidum

What species of chlamydia is reportable?

chlasmydia psittici

What species of chlamydia are zoonotic?

c. abortus, c. felis, c. pneumonia, c. psittici

what's the only hemotrophic mycoplasma we learned?

myocplasma haemophilus -- all others are NON hemotrophic

mycoplasma haemophilus causes hemolytic anemia in what species?

cats

What is a clinical sign of swine dysentery?

bloody diarrhea

What causes porcine proliferative enteritis?

Lawsonia intracellularis

What is a clinical sign of porcine proliferative enteritis?

non-bloody diarrhea ('garden hose' duct)

True or false: dermonecrotic toxin is produced by pasteurella?

false. produced by bordetella

What are the five toxins of bordetella? What do they do?

1) Trachael cytotoxin - damages ciliated epithelial cell 2) dermonectrotic toxin - affects actin cytoskeleton, inhibits osteoblasts (atrophic rhinitis) 3) adenyl cyclase toxin - pore forming, rereg. ion and fluid flow, hemolytic, reduces phagocytic capacity of leukocytes 4) pertussis toxin (B. pertussis only) - loss of fluids and ions, inhibits phagocytes 5) osteotoxin - lethal to trachael and bone cells

Where does brucella multiply in cells?

inside macrophages

Is brucella reportable?

yes

Is brucella zoonotic?

yes

Does brucella cause abortion?

Yes, in cows, people, swine and dogs

Is Brucella a problem in the US?

Yes because of wild pigs and animals (deer)

T/F: Both Lawsonia and Chladmydia are intracellular?

TRUE

Name reportable diseases (There are ____)

Burkholderia mallei

What color is pseudomonas on MacConkey Agar?

colorless

What causes pseudomonas to appear lime green?

blue pyocyanin (virulence factor) and yellow fleuroscin

How can you distinguish Burkholderia pseudomallei from mallei?

pseudo is motile (and grows on cepacia agar?) | pseudo causes meliodosis and pseudoglanders

how can you distinguish melioidosis from glanders?

glanders -- horses and cats mainly meliodosis mainly sheep and goats glanders - B mallei (non motile) meliodosis - B pseudomallei (motile)

What causes whitemore's dz in humans?

Burkholderia pseuodmallei "vietnamese time bomb"

What causes CEM contagious equine metritis?

Taylorella equigenitalis

What causes swine dysentery?

Brachyspira hyodysenteriae (growing pigs 6-12 weeks)

Swine dysentery affects what age group of swine?

growing pigs, 6-12 weeks

What causes proliferative enteropathy in pigs, horses, mammals and birds?

lawsonia intracellularis

the leading cause of food-borne bacterial gastroenteritis in humans

C jejuni and C coli

necrotic donut hole shaped lesions are pathognomonis for what?

ovine camplylobacter: c. jejuni or c. fetus ssp fetus

What is found in 50% of the ceca of chickens?

Campylobacter jejuni

how can you distinguish campylobacter from acrobacter?

campylobacter will not grow below 30 degrees C but arco will

What causes "weak calf syndrome"

leptospira ser. hardio

What is the tick vector for borellia anserina?

argas persicus (soft tick)

what causes infectious sinusitis in turkeys?

mycoplasma gallisepticum

what causes sternal bursitis in turkeys?

mycoplasma synovial

what causes contagious bovine pleuropneumonia (CBPP)

mycoplasma mycoides ssp mycoides SMALL COLONY

True or false: mycoplasma are normal commensal organisms of the lower urogenital tract?

true -- dz usually in overcrowded/stressed animals

What does mycoplasma mycoides ssp mycoides LARGE colony cause?

mastitits, pneumonia, septicemia in kids