Final Exam Prep Flashcards

1
Q

The blood test most commonly used to confirm the existance of heart muscle damage is:

A

Creatine Kinase

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2
Q

The diagnosis of acute myocardial infarction consists of the following “triad”:

A

chest pain,
ECG changes,
Elevation of biomarkers

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3
Q

An ideal marker should appear in the blood quickly after an infarct and then be rapidly cleared from the blood.

T / F

A

False

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4
Q

Marker Responses to MI curve, which one is the highest one (B)?

A

Cardiac Troponin

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5
Q

Marker Responses to MI curve, which one is the lowest one (D)?

A

Cardiac troponin after unstable angina

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6
Q

Marker Responses to MI curve, which one is the Average one (C)?

A

CKMB

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7
Q

Marker Responses to MI curve, which one is the narrowest one (A)?

A

Myoglobin

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8
Q

Creatine Kinase (CK) lacks specificity for cardiac damage and, therefore, needs to be augmented with the CK-MB fraction.

T / F

A

True

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9
Q

CK-MM (98%) :

CK-MB (1%)

A

Skeletal muscle expression of creatine kinase

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10
Q

CK-MM (70%) :

CK-MB (30%)

A

Cardiac myocardial expression of creatine kinase

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11
Q

CK-BB

A

Expressed mainly in the tissues, little significance in blood straem

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12
Q

CK/CPK

A

catalyzes the conversion of creatine to phosphocreatine degrading ATP to ADP

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13
Q

Troponin-C (TnC)

A

binds to Ca++ ions to produce a conformational change in TnI

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14
Q

Troponin-I (TnI)

A

binds to actin in thin myofilaments to stabilze troponin-tropomyosin complex

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15
Q

Troponin-T (TnT)

A

binds to tropomyosin forming the troponin-tropomyosin complex

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16
Q

Tropomyosin

A

a thin filament element

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17
Q

Troponin as a marker: Which Troponin have studies failed to find a source outside the heart?

A

Troponin-i

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18
Q

Which biomarker may provide prognostic information (ie. peak levels corelate with infarct size)

A

Tni

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19
Q

Myoglobin is released into the blood in detectable range as early as

20
Q

A non-dominant left coronary artery is almost always more important than the dominant RCA.

T / F

21
Q

A major limitation of coronary arteriography is:

A

it only provides a luminogram that provides no onformation about the vessel wall

22
Q

Coronary arteriograpy visulizes only the major epicardial branches.
T / F

23
Q

In 1929, who performed the first right heart cardiac catherization (upon self!)?

24
Q

List 2 complications of Cardiac Catherization

A

Arrhythmias

Renal insufficiency

25
List 3 Pitfalls of Coronary Arteriography
1. ) Difficulty in detecting ostial left main. 2. ) Superinmposition of branches. 3. ) Unrecognized branches
26
Diagnostic Cardiac Catherization provides lots of information to the clinician. Along with Coronary Arteriography, what 2 other areas will this procedure allow acquisition of data?
1. ) Left Ventricolography | 2. ) Hemodynamic data
27
How many coronary angiograms are done annually in the USA?
1,000,000
28
Vascular access to perform cardiac catherization is most often obtained via the:
Femoral artery
29
What is the major cation of extracellular fluid?
Sodium (Na)
30
What is the major anion of extracellular fluid?
Chloride (Cl)
31
During a fasting plasma glucose test, a value of >140 mg/dl on more than one occasion is diagnostic for diabetes mellitus. T / F
True
32
Low levels are a risk factor for coronary artery disease.
HDL-Cholesterol
33
is the "bad" cholesterol
LDL-Cholesterol
34
``` Electrolytes normal plasma values: Na = K = Cl = Glucose = ```
``` Na = 135 - 146 K = 3.5 - 5.5 Cl = 95 - 109 Glucose = 60 - 109 ```
35
Which of the following are considered renal function tests?
BUN & creatinine
36
In urinalysis, a positive nitrite test indicates
that bacteria may be present in significant numbers
37
Crystals in the urine indicates that
conditions are right for kidney stones to be made
38
Is a result ofbleeding into the bladder or urinary & can be caused by catheter placement
Hematuria
39
Urine which is reddish brown in color
All of the above
40
Albumin in the urine is significant because it may indicate
kidney disease
41
Normal urine pH is
6.0 - 7.0
42
In urinalysis, the presence of Ketones in the urine could indicate
kidney stones
43
Acute tubular necrosis may result from
Blunt Trauma
44
Medical Technologists no longer routinely test and report urine odor. T / F
True
45
The presence of glucose in the urine can most often be seen in this patient group
diabetics
46
Protein casts tend to dissolve in alkaline medium. T / F
True