FINAL EXAM - FIBER, PROTIENS, LIPIDS Flashcards

1
Q

From where does fiber come?

A

plants

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2
Q

In what place(s) can we get fiber in our diet? Where do we NOT get fiber?

A

CAN get fiber from beans, peas, veggies, fruits, whole grains
CAN’T get fiber from meat, dairy, eggs, junk food

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3
Q

Burkitt, et. al. study concerning the diets and colon cancer rates of those in Sub-saharan Africa

A
  • Africans USED to eat a lot of fiber, but now live on highly refined corn meal, which is LOW in fiber
  • Africans also have a low colon cancer rate
  • lacking fiber BUT ALSO lacing animal protein and fat
  • blacks in South Africa had acidic poop despite comparable fiber intakes, but sub-saharan Africans had these high SCFAs -> resistant starch
  • resistant starch acts in the same way as fiber in colon, as a prebiotic
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4
Q

insoluble fiber vs. soluble fiber

A

INSOLUBLE = fiber that doesn’t dissolve in water; considered “gut-healthy” b/c of laxative effect; adds bulk to diet; helps prevent constipation; “broom” for GI tract

SOLUBLE = fiber that dissolves in water; attracts H2O, forming a gel that delays gastric emptying, making you feel full; beneficial for insulin sensitivity; can help lower LDL

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5
Q

How many Americans get enough fiber in their diet?

A

3% get enough fiber in their diet

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6
Q

What is the 5:1 rule?

A

for every 5 grams of carbohydrates we eat, we should aim for 1 gram of fiber (if not at 5:1, at least get as close to it as we can for any given food/meal)

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7
Q

5 fiber facts from The Gut Health M.D. podcast?

A
  1. fiber is consistently associated with longevity (decreased risk in having AND dying from a heart attack, stroke, diabetes, colon cancer; live longer, lose weight)
  2. fiber is the preferred food of the gut bacteria
  3. fiber rewards us with short-chain fatty acids (a postbiotic), which has many healing benefits
  4. all plants contain fiber, especially prebiotic fiber; all plants feed different microbiomes; aka the sources of our fiber intake matter!
  5. eating a diversity of plants for every meal is the best way to optimize gut microbiome
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8
Q

Relationship b/w SCFAs and the human microbiome?

A
  • provides energy to the cells of colon
  • aids in formation of mucus
  • regulates body’s inflammatory response
  • possesses anti-cancer effects
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9
Q

Quick Fiber check tool

A

this awards points to types of food a person eats in a day (7 points to beans/lentils, which are high in fiber, all the way down to 0 points for no-fiber foods like meat, dairy, eggs, soda)

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10
Q

What is some ARCHEOLOGICAL evidence that suggests that humans have evolved to be predominantly plant eaters?

A
  • tools used for plant processing, like grinding stones and mortars
  • presence of plant seeds at archeological sites (Turkey and Rome - gladiators were most likely vegetarians)
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11
Q

What is some ANTHROPOLOGICAL evidence suggesting that humans have evolved to be predominantly plant eaters?

A
  • dental structure = we have rounded, square teeth while carnivores have triangular, sharper teeth
  • digestive tracts = relatively long (also true of other herbivores)
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12
Q

What is the impact of plant-based eating (even a single meal) on blood flow?

A
  • a single ANIMAL-based meal can impair blood flow, with up to 27% decrease in endothelial function
  • plants improve endothelial function and blood flow
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13
Q

Protein digestion and how ammonia is safely removed from the body?

A
  • when proteins are digested, they are broken down into constituent amino acids
  • these AA’s -> deamination = removing amino group, which contains N
  • nitrogen converted to ammonia
  • liver converts ammonia into urea
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14
Q

What is the WFPB diet and its relationship w/ heart disease?

A

WFPB - whole foods plant-based diet that emphasizes whole unprocessed foods, limiting/excluding animal products

  • associated w/ lower risk of CVD b/c of positive effects on cholesterol levels, BP, and inflammation
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15
Q

proinflammatory compounds and animal products?

A
  • saturated fats
  • heme iron
  • advanced glycation end products (AGEs)
  • arachidonic acid
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16
Q

Global Burden of Disease study

A

= largest study of risk factors for disease in history
- concluded that the NUMBER ONE cause of premature death in the U.S. AND number one cause of disability is the standard American diet (high intakes of meat, dairy produced, refined grains and sugars; low intakes of fruits, veggies, whole grains, nuts, seeds)

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17
Q

Of what are proteins composed?

A

amino acids!

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18
Q

What’s the idea behind “complete” and “incomplete” sources of protein?

A

this basically says that sources of protein that have all 9 essential amino acids are COMPLETE and any source of protein that doesn’t is INCOMPLETE

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19
Q

Are plants “incomplete” proteins?

A

No b/c all plants contain all essential amino acids

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20
Q

What is protein turnover?

A

the cycle involving both protein SYNTHESIS and protein DEGRADATION in the body; helps maintain an adequate supply of amino acids

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21
Q

How likely is protein DEFICIENCY vs. protein EXCESS?

A

protein deficiency is not a concern in industrialized countries, but common in regions where the amount and variety of foods are limited; protein excess does not cause adverse health outcomes

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22
Q

Kwashiorkor’s disease

A

a form of protein-energy malnutrition often characterized by extensive edema (swelling) in the extremities (hands, feet); often starts in the legs but later involves the entire body -> abdominal distention and intestinal parasites

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23
Q

Marasmus

A

a form of protein-energy malnutrition characterized by extreme wasting of muscle and adipose tissue; skin hangs on in folds

24
Q

What are the key steps involved in protein digestion?

A
  1. Gastric cells release gastrin, which enters the blood, causing the release of gastric juices.
  2. HCl in gastric juices denatures protein & converts pespinogen to pepsin, which begins to digest proteins by hydrolizing peptide bonds.
  3. Partially digested proteins enter the S.I. and cause secretin and CCK to be released.
  4. Secretin stimulates pancreas to release bicarbonate into the intestine, which neutralizes chyme. CCK stimulates pancreas to release proenzymes into S.I.
  5. Additional proenzymes are converted to active enzymes. These enzymes digest polypeptides into tripeptides, dipeptides, and free A.A.’s.
  6. Intestinal enzymes in the lumen of S.I. and within mucosal cells complete protein digestion.
25
Q

What are some of the important functions of proteins in the human body?

A
  • provide structure of tissues such as bones, teeth, and skin
  • catalysis to make up enzymes
  • allow movement through our muscles, ligaments, and tendons
  • involved in the transport of substances across cell membranes and within circulatory system
  • communicate via protein hormones and cell-signaling proteins
  • protect our skin (collagen) and immune system (antibodies)
  • regulation of fluid balance
  • regulation of pH (hemoglobin)
26
Q

What is the point of the urea cycle?

A

to make sure that the ammonia produced via deamination is converted into a substance that the liver can handle

27
Q

saturated fats

A

fatty acids that contain ONLY carbon-carbon SINGLE bonds in their backbone; best to consume in moderation; increases total cholesterol and LDL cholesterol

28
Q

monounsaturated fats

A

fatty acids that contain ONE carbon-carbon double bond in their backbone; considered a healthy fat; lowers LDL and maintains HDL

29
Q

polyunsaturated fats

A

fatty acids that contain more than one carbon-carbon double bond in their backbone; an essential fat; lowers LDL

30
Q

WHO trans fat ban

A

the WHO called for a global elimination of industrially produced fatty acids from the food supply b/c of the link b/w them and the increased risk of heart disease; as of 2020, 32 countries had implemented mandatory trans fatty acid limits, impacting 2.4 billion people

31
Q

What have studies shown regarding trans fats?

A

links trans fats to diminished memory, increased risk for heart disease

32
Q

The 4 steps of lipid digestion

A
  1. Lingual lipase is released in the mouth, causing a minor amount of lipid digestion.
  2. Gastric lipase in the stomach removes some more fatty acids for additional digestion.
  3. Bile emulsifies the lipids when they immediately enter the small intestine, transforming the fats into smaller stabilized micelles.
  4. CCK and secretin are signaled, pancreatic lipase is produced and removes some fatty acids, and triglyceride digestion is finalized via hydrolysis and simple diffusion.
33
Q

What are the REQUIREMENTS for the digestion of lipids?

A
  • emulsification
  • lipases (gastric, lingual, pancreatic)
  • bile salts
  • micelle formation
  • absorption
34
Q

For what process is bile responsible?

A

the emulsification of fats

35
Q

Where does lipid digestion start?

A

lipid digestion starts in the mouth

36
Q

What enzymes are involved in LIPID digestion?

A

lingual lipase, gastric lipase, bile, pancreatic lipase, CCK, secretin

37
Q

What is cholesterol, and where is it found?

A

a sterol found in animal foods and made in the human body; required for bile acid and steroid hormone synthesis

38
Q

glycolipids

A

lipids with a carbohydrate attached by a glycosidic bond; meant to maintain the stability of cell membrane and facilitate cellular recognition

39
Q

Alli (Orlistat)

A
  • # 1 Dr. recommended OTC weight loss aid
  • best to use it in conjunction w/ a reduced fat, low-cal diet
  • when taken before a meal, it attaches to enzymes in the body and blocks about 25% of fat from being digested
  • undigested fat passed out of body, so caloric deficit!
40
Q

phospholipids

A

a type of lipid composed of a glycerol bonded to two fatty acids and a polar head group

41
Q

lipogenesis

A

the metabolic processes that result in fatty acid and, ultimately, triglyceride synthesis

42
Q

lipolysis

A

the breakdown of triglycerides into fatty acids and glycerol

43
Q

adipocytes

A

specialized cells that make up the majority of adipose tissue

44
Q

ketones

A

acids your body releases when it burns fat instead of glucose for energy; having these means your body is using backup energy source

45
Q

emulsification

A

the process whereby large lipid globules are broken down and stabilized into smaller lipid droplets

46
Q

partial hydrogenation

A

a process whereby some carbon-carbon double bonds found in PUFAs are converted to C-C single bonds, resulting in the production of a lipid containing saturated and trans fatty acids

47
Q

omega-3 fatty acids

A

a fatty acid in which the FIRST C-C double bond is located b/w the 3rd and 4th carbons from the methyl (omega) end

48
Q

omega-6 fatty acids

A

a fatty acid in which the first double C-C- bond is located b/w the 6th and 7th carbons from the methyl (omega) end

49
Q

What is the RELATIONSHIP b/w omega-3’s and omega-6’s?

A

omega-3 = ANTI-inflammatory
omega-6 = PRO-inflammatory

50
Q

components of a fatty acid

A
  • hydrocarbon chain
  • alpha end = carboxylic acid (COOH)
  • omega end = methyl group (CH3)
51
Q

What are the top sources of saturated fat in the standard American diet?

A

red meat, whole milk, cheese, hot dogs, lunch meat

52
Q

cis fatty acids vs. trans fatty acids

A

CIS fatty acid - Hydrogens are on the SAME SIDE of the fatty acid backbone, so —\—
TRANS fatty acids - Hydrogens are on OPPOSITE SIDES of fatty acid backbone, which makes it more STABLE, so ———

53
Q

COMPONENTS of fiber?

A

cellulose, starch, hemicellulose, lignans, pectins, suberin, cutin, and waxes

54
Q

Sources of OMEGA -3 FATTY ACIDS?

A

linolenic acid; canola, soybean, flaxseed, other seed oils; marine algae; fish oils; animal fats

55
Q

sources of OMEGA-6 fatty acids?

A

LINOLEIC acid; nuts, corn, safflower, soybean, cottonseed, sunflower seeds, peanut oil