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Systems Pathology I > Final Exam > Flashcards

Final Exam Flashcards

1
Q

Rhumatoid arthritis associated with skin disease and what HLA does it have?

A

Psoriatic Arthritis HLA-B27

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2
Q

Which disease is juvenile RA and produces a rash and fever?

A

Still’s Disease

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3
Q

Which disease has unilateral bone lesions, cafe au lait spots, fibrous displasia and percoscious puberty?

A

McCune Albright

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4
Q

Unexplained hematuria, history of unexplained nephritis, end stage renal disease, hearing loss, occular lesions, familial history of nephritis

A

Alpert Nephritis

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5
Q

Which type of diabetes myelitis is found in children and is insulin dependent?

A

Type I Diabetes Mellitus

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6
Q

Which type of diabetes Mellitus is there peripheral neuropathy and HLA-DR3 and HLA-DR4?

A

Type II Diabetes Mellitus

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7
Q

Which type of meningitis has bacteria, turbid CSF with neutrophils, and is treated with antibiotics?

A

Acute purulent meningitis

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8
Q

What are the 4 common symptoms of leptomeningitis?

A

Nuchal rigidity
Headache
Vomiting
Papiledema

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9
Q

Which leptomeningitis is a associated with viruses, clear CSF, lymphocytes?

A

Acute Lymphocytic Meningitis

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10
Q

Which type of meningitis is associated with TB, chronic granulomatous inflammation, insidious onset, personality changes?

A

Chronic meningitis

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11
Q

Disease in which patient has epigastric pn. Radiates to back, increase in amalase lipase and peptidase.

A

Acute Pancreatitis

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12
Q

Destroying of all the cells, enzymatic fat necrosis, development of diabetes, risk of pancreatic adenocarcinoma in the head of pancreas.

A

Chronic pancreatitis

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13
Q

What two diseases have cafe au lait spots?

A

Neurofibromatosis (Von recklinghause disease)

And

McCune Albright Disease

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14
Q

Which arthritis is associated with IBD?

A

Enteropathic arthritis

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15
Q

Congenital disease causing hydrocephalus in which the cerebellar tonsils extend down into the foramen magnum

A

Arnold Chiari malformation

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16
Q

What two congenital diseases cause noncommunicating hydrocephalus?

A

Stenosis of Cerebral Aqueduct

Arnold Chiari malformation

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17
Q

Which two tumors can cause acquired, non-communicating hydrocephalus?

A

Ependomoma

Meduloblastoma

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18
Q

Most common disorder of the female breast

A

Fiborcystic disease

19
Q

Breast lesion, benign, no risk of cancer, fibrosis, cystic dilation, no epithelial hyperplasia

A

Nonproliferative fibrocystic disease

20
Q

Breast lesion that has 5x increased risk of cancer in atypical ductal epithelial cells, epithelial hyperplasia with cysts and fibrosis

A

Proliferative Fibrocystic Disease

21
Q

Breast lesion that can look like cancer but it is not, back to back glands (like adenocarcinoma), slight risk for cancer

A

Sclerosing adenosis

22
Q

What are the two benign tumors of the breast?

A

Fibroadenoma

Intraductal papilloma

23
Q

Most common benign tumor of the breast, young females, estrogen dependent, loose fibroblast in stroma with ducts and acini with one layer of cuboidal cells

A

Fibroadenoma

24
Q

Benign tumor of the breast, subareolar, bloody nipple discharge, unilateral

A

Intraductal Papilloma

25
Q

Most common malignant tumor of the breast, prolonged exposure to estrogen

A

Ductal carcinoma

26
Q

Noninvasive malignant tumor of the breast, confined to the ducts, calcification and central necrosis - ccc is funny to me

A

Comedocarcinoma

27
Q

Malignant tumor of the breast that has lymphocytic infiltrates

A

Medullary carcinoma

28
Q

Malignant tumor of the breast with cells with clear halo due to mucopolysacharides, with tumor cells in epidermis beneath nipple

A

Paget’s disease of the breast

29
Q

Malignant tumor of the breast in which cells line up in a row “Indian file”

A

Invasive lobular adenocarcinoma

30
Q

What kind of nodules will you have with alcoholic cirrhosis?

A

Micronodular

Macrovasicular

31
Q

What kind of nodules are found with non-alcoholic cirrhosis?

A

Macronodular

32
Q

What kind of nodules would you find in the liver with Wilson’s disease - hint, upside down W

A

Mixed micronodular and macronodular

33
Q

What is the most common cause for chronic liver disease in the US?

A

Hepititis C

34
Q

What is the most common cause for chronic liver disease in the western world?

A

Alcohol abuse

35
Q

What is the most common cause of acute and chronic liver disease?

A

Alcohol abuse

36
Q

Which multiple endocrine neoplasia is associated with parathyroid hyperplasia, pancreases insulinoma, pituitary gland, aka Werner Syndrome?

A

MEN I

37
Q

Which Multiple endocrine neoplasia is associated with parathyroid hyperplasia, thyroid medullary carcinoma, adrenal gland (pheochromocytoma), aka sipple syndrome, remember pta

A

MEN IIA

38
Q

Which multiple endocrine neoplasia is associated with thyroid carcinoma and pheochromocytoma, aka William syndrome - remember “prince William is a boy”

A

MEN IIB

39
Q

What blood vessel is affected with epidural hematoma?

A

MMA

40
Q

What cranial blood vessel is lesioned with a subdural hematoma?

A

Bridging veins

41
Q

Which blood vessel is leisioned with cerebral hemorrhage and malignant hypertension?

A

Lenticulostriate branch of MCA

42
Q

What blood vessel is lesioned with subarachnoid hemorrhage?

A

Circle of Willis

43
Q

Which malignant tumor has rapid growth, arise from striated muscles, affects extremities, retroperitoneal and orbit, affects children below 10 years, rapid growth, early metastasis

A

Rhabdomyosarcoma

44
Q

Sialadentitis of all salivary glands including lacrimal gland - keratoconjuctiivitis = dry eye
Xerostomia = dry mouth
Autoimmune

A

Sjorgren syndrome

Systems Pathology I (6 decks)

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