Final Exam Flashcards
An atom or group of atoms that has an unpaired (extra) electron and is therefore unstable and highly reactive
Free radical
Chemically reactive molecules containing oxygen
Reactive oxygen species (ROS)
An imbalance between the production of reactive oxygen species and the bodies ability to detoxify the free radicals or repair damage
Oxidative stress
Enzyme that is part of the detoxification of reactive oxygen species
Superoxide dismutase (SOD)
Aβ peptide in amyloid plaques
Alzheimer’s disease
Hyperphosphorylated tau
Neurofibrillary tangles
α-synuclein
Lewy bodies
Hippocampus, cortical and limbic structures
Alzheimer’s disease
Substantia nigra (& linked cortical regions)
Parkinson’s disease
Spinal cord (and precentral gyrus -part of the primary motor cortex)
ALS
Subcortical brain structures that are crucial in planning, organizing and executing movement, addiction
Basal ganglia
Nucleus in the basal ganglia involved in initiating voluntary movement. Contain a lot of dopaminergic neurons
Substantia nigra
One of the three major classes of glia in nervous system, controls the ionic environment of neurons and can be involved in neurotransmitter reuptake
Astrocyte
Stimulus that produces a natural, automatic reaction; food is the most famous example, but there are many things you respond to without learning
Unconditioned stimulus
Previously neutral stimulus that, after repeated association with an unconditioned stimulus, elicits the response produced by the unconditioned stimulus itself
Conditioned stimulus