final exam Flashcards

1
Q

1) What and where is Camp Lejeune?

A

d) Marine base in North Carolina

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2
Q

2) What’s another name for a site listed on the EPA’s National Priority List?

A

d) Superfund Cleanup site

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3
Q

3) How long has the base been polluting its own drinking water?

A

d) 30 years

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4
Q

4) Tap water at an elementary school in Camp Lejeune had ____________ ppm of TCE in it. That’s ___________ times the levels recorded in Woburn, MA, which was made famous in the film A Civil Action.

A

c) 1,184, 5x

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5
Q

5) What site has had the most contaminated public drinking water ever discovered in the US, and how many people drank it?

A

a) Camp Lejeune, 750,000

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6
Q

6) What disease is associated with this polluted drinking water?

A

c) male breast cancer

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7
Q

8) When did Partain first hear about the link between the pollution at Camp Lejeune and weird diseases?

A

d) 2007

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8
Q

9) When did the military know there was a potentially hazardous contamination problem at Camp Lejeune?

A

c) 1982

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9
Q

10) When the author wrote her book, how many men had contacted Partain about their illness?

A

71

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10
Q

11) Why is it easier to study breast cancer in men than in women?

A

c) Because men’s risk factors aren’t complicated by age at puberty, life history, and HRT.

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11
Q

12) What is the cost estimate for cleaning up the base?

A

c) $200 million tax payer dollars

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12
Q

13) Why do epidemiologists have an easier time dealing with male breast cancer rates at Camp Lejeune than in other places?

A

c) So many men have come forward that statisticians have enough numbers to provide probable links.

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13
Q

14) Do epidemiological studies apply to individuals or populations?

A

c) Populations because epidemiology deals with averages.

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14
Q

15) What percent of the nation’s drinking water has TCE in it?

A

d) 34%

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15
Q

16) When did the EPA reclassify TCE as a known human carcinogen?

A

d) in 2011

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16
Q

17) True or false: Solid evidence links TCE to kidney cancer and suggestive evidence links it to neurotoxicity, immunotoxicity, developmental toxicity and endocrine effects.

A

true

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17
Q

19) Who is Margaret Kripke?

A

b) an immunologist at University of Texas MD Anderson Cancer Center

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18
Q

20) Margaret Kripke was a skeptic on the topic of environmental disease. What changed her mind?

A

d) She learned the industry could put chemicals on the market without testing them for safety first.

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19
Q

21) To qualify for service-related illness benefits, veterans must prove that ________ had a 50 percent chance of causing their problems.

A

a) An environmental exposure

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20
Q

22) When breast cancer runs in families, what other kind of cancer is linked with it?

A

c) ovarian

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21
Q

23) Of women who reach the age of 90, what percent will get breast cancer?

A

b) 12%

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22
Q

24) Mammograms miss __________ percent of all tumors.

A

c) 20

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23
Q

25) What is BSE?

A

d) Breast Self Exam

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24
Q

1) What two free-ranging animals contract breast cancer?

A

c) Humans and minks.

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25
Q

2) Do all human populations get breast cancer?

A

b) The Kaingan women of Brazil don’t get breast cancer.

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26
Q

3) How long have humans known about breast cancer?

A

d) The ancient Egyptians knew about it.

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27
Q

4) In an attempt to cure one woman’s breast cancer, Beatson did what?

A

c) He removed her ovaries, and it provided a temporary cure.

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28
Q

5) “Epidemiologists are people who use ______________ to study ______________.”

A

c) statistics , diseases

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29
Q

6) Why did Pike compare Japanese women to American women?

A

a) Because American women get breast cancer at a 6 times higher rate than Japanese women.

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30
Q

7) What did Pike conclude?

A

d) Weight at first menstruation and age at puberty explain half the difference in breast cancer rates.

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31
Q

8) What does progesterone do?

A

a) Inhibits the release of additional eggs so women get pregnant only once at a time.
b) Prevents ovulation.

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32
Q

9) Does the pill increase or decrease the risk of ovarian cancer?

A

a) The pill decreases ovarian cancer because it reduces cellular division and growth.

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33
Q

10) What is Pike’s hypothesis?

A

d) That the more menstrual cycles a woman experiences in her lifetime, the more her breasts are flooded with whiplashing hormones, increasing her probability of breast cancer.

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34
Q

11) In the mid-1980’s Pike was publishing papers that said what?

A

c) Women taking the pill as teens doubled their risk of breast cancer before the age of 45.

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35
Q

12) If the risk of something is very low (like 0.13%), and you double it, is it still very low?

A

b) yes

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36
Q

13) What does HRT stand for?

A

b) hormone replacement therapy

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37
Q

14) How might menopause be adaptive?

A

a) It allows grandmothers to care for grandchildren, freeing the mother.

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38
Q

15) What did HRT do to breast cancer rates?

A

b) increased rates by 26%

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39
Q

16) A 100 percent increase in something is the same as _______________.

A

b) doubling it

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40
Q

17) “We’re pretty much marinating in ________________ and _______________.”

A

b) hormones, toxins

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41
Q

1) According to Hartmann, the breast is the only organ without ________________.

A

b) A medical specialty

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42
Q

2) True or false: The metabolic energy required by a lactating woman to feed her infant is 30% of her total output.

A

true

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43
Q

3) What did the Human Microbiome Project, a project set to decode the microbial genes of every major human gland, fail to include?

A

b) breast milk

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44
Q

4) How many ounces of milk does the average new mother make in a 24-hour period?

A

c) 16

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45
Q

5) How many species of bacteria did Mark McGuire find in human breast milk?

A

800

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46
Q

6) What do oligosaccharides feed?

A

d) the bacteria in the guts of newborn babies

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47
Q

7) The incidence of NEC is ________ percent lower in breast-fed babies than in formula-fed babies.

A

77

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48
Q

8) What is NEC?

A

d) an illness that causes the lower intestine to shrivel and die

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49
Q

9) Where does Newburg find his disease-causing organisms?

A

a) in baby poop

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50
Q

10) Newburg noticed something about rats that made him change his career. What was it?

A

b) Formula fed rats were dumber than nursed rats.

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51
Q

11) ___________ occurs naturally in breast milk. It acts as an anti-inflammatory agent, an antioxidant, and an anti-infectoice glycoprotein.

A

b) Lactoferrin

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52
Q

12) When human breast milk is pasteurized, what happens to it?

A

d) The bioactive ingredients in it die.

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53
Q

13) Dr. Bruce German said the following: “This whole story is part of a revolution in science itself, where the _______________________ science of the twentieth century is giving way to the ___________________ science of the twenty first century.”

A

a) chemistry dominated, biology-dominated

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54
Q

14) Who is Katherine Hinde?

A

b) A human evolutionary biologist who studies monkeys at Harvard.

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55
Q

15) According to Hinde, macaque mothers make______________ milk for their daughters and ____________ milk for their sons.

A

c) Thin but abundant, fatty

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56
Q

16) What do endocannabinoids do?

A

b) make babies feel full after they’ve consumed breast milk

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57
Q

17) True or false: breasts make the same kind of milk for a sick baby and a healthy baby.

A

b) false

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58
Q

18) True or false: As a baby gets older, the milk gets more fat and cholesterol in it.

A

a) true

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59
Q

19) Breast-feeding reduced heart disease/type II diabetes by _______ %

A

c) 10

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60
Q

20) True or false: At least nine dangerous chemicals can be found in breast milk that do not belong there.

A

true

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61
Q

22) Why do people spray flame-retardants on polyurethane products?

A

b) Because polyurethane products burn easily.

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62
Q

24) Are mattresses soaked in flame-retardants?

A

a) no

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63
Q

25) Why do flame retardants end up in breast milk?

A

a) Because PBDE’s love fat.

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64
Q

26) Did doctors ever find DDT in human breast milk?

A

b) yes

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65
Q

27) Have researchers ever found PCBs in human breast milk, even after the ban?

A

b) Yes

66
Q

28) At the molecular level, what does PBDE resemble?

A

c) PCBs

67
Q

29) Does PBDE regularly show up in breast milk?

A

yes

68
Q

30) High levels of PBDE in babies and toddlers are associated with ___ according to a 2010 study in New York.

A

a) lower performance IQ
b) lower verbal skills
c) slower physical development

69
Q

31) Do breast-fed infants have higher levels of chemicals in their bodies compared to their formula-fed colleagues, and does the difference persist?

A

d) Yes, but bottle-fed kids catch up by mid-childhood

70
Q

32) “It was not until persistent organic chemicals began appearing in human milk that countries_____________________________________.”

A

c) took steps to ban them

71
Q

33) Why might it be a bad idea for women to loose weight while nursing?

A

c) Because a mom might dump her toxins into her kid

72
Q

34) Why did the author send her house dust to be tested?

A

c) To see if she had toxins in her dust

73
Q

36) What was tris linked to in the 1970’s?

A

a) DNA mutations

74
Q

37) Which countries soak their furniture in flame-retardants?

A

d) The US and UK

75
Q

38) Has the US ratified the 2004 UN treaty that bans or restricts 21 of the worst persistent chemicals?

A

no

76
Q

1) A woman who has her first child before the age of ___________ has about half the lifetime risk of breast cancer as a non-mother or a mother who waits until her thirties to have children.

A

20

77
Q

2) What do over-the-counter pregnancy testers measure?

A

b) Human chorionic gonadotropin

78
Q

3) What is the leading hypothesis regarding the role of pregnancy and cancer?

A

a) As breasts become more fully mature at the end of pregnancy, their stem cells turn into cancer-resistant dairy equipment.

79
Q

4) In humans, known genetic factors account for about _________% of all breast cancers.

A

10

80
Q

5) True or false: “lobules type 1” are less prone to cancer than are lobules type 4.

A

false

81
Q

6) Do type 1 or type 4 lobules have more receptors for estrogen?

A

1

82
Q

7) What does HCG in human urine do to plants?

A

d) stimulates seed growth

83
Q

8) How did ancient Egyptians take advantage of the effect of HCG on plants?

A

c) created an early pregnancy test

84
Q

9) What was the gist of the paper published by Janet Daling?

A

d) Women who had abortions before the age of 18 were more likely to get breast cancer.

85
Q

11) What is involution?

A

a) What happens to breasts after they’re finished lactating.

86
Q

12) Gross was aware of a non-intuitive finding. What was it?

A

d) Sometimes, directly after childbirth, a fast and horrible breast cancer can develop.

87
Q

13) What is Schedin’s “involution hypothesis”?

A

b) During breast involution, tiny growths break free inside milk ducts, tap into blood veins, and produce cancerous growths.

88
Q

14) Why do some researchers think the breast is so plastic and poised to respond?

A

a) Because breasts need to be ready to feed that baby asap.

89
Q

15) Is breast-feeding always easy and natural for humans?

A

b) No. Some women struggle with it.

90
Q

16) What is mastitis?

A

d) An infection in the milk ducts

91
Q

17) Which babies sleep through the night: bottle-fed babies or breast-fed babies?

A

b) Bottle-fed babies because the formula takes longer to digest.

92
Q

18) If a mom hires a wet nurse, what happens to mom’s fertility?

A

d) It increases because mom isn’t making prolactin, which suppresses ovulation.

93
Q

19) Why does the author describe breast-feeding as an “ingeniously calibrated feedback loop?”

A

e) Because the breast changes the milk it makes depending on the baby’s needs.

94
Q

20) When was the first baby formula sold worldwide?

A

1870

95
Q

21) True or false: Breast-feeding fell out of fashion when people started to understand germ theory.

A

true

96
Q

22) Infant formula confers a drop of ________ IQ points.

A

4

97
Q

23) Childhood lead levels (coming from paint and leaded gasoline) conferred a drop of _____________ IQ points.

A

4

98
Q

1) What is benzophenone, and where did the author find it?

A

d) An endocrine disruptor found in “green” hand soap

99
Q

2) NIEHS and NCI spent $40 million to try to understand the link between ________ and_____.

A

c) Early puberty, cancer

100
Q

3) Currently, at what age do girls start budding, on average?

A

a) 8.8-9.8 years

101
Q

4) Even before we were dumping fake estrogens into the environment, what was happening to the age of sexual maturity in the US? Why?

A

b) Getting earlier because of good nutrition

102
Q

5) How long does a human need to grow a fully mature prefrontal cortex?

A

d) About 20 years

103
Q

6) What does the prefrontal cortex do?

A

c) Governs self-control

104
Q

7) What do you suppose happens when the body reaches maturation long before the prefrontal cortex?

A

c) People make bad decisions

105
Q

8) Why do some people call fat “the third ovary?”

A

b) Because it can make estrogen

106
Q

9) What two dietary ingredients seem to delay puberty?

A

c) Fiber and vegetables

107
Q

10) Does fat always trigger puberty?

A

a) No. Skinny girls sometimes hit puberty first.

108
Q

11) Does puberty always start with budding or does it always start with pubic hair.

A

c) Sometimes starts with budding and sometimes starts with pubic hair.

109
Q

12) Who is Lise Aksglaede?

A

b) A pediatric endocrinologist at the University of Copenhagen

110
Q

13) What did Aksglaede discover when she compared the timing of budding in 2006 and 1991 in her hometown?

A

a) Girls budded a year earlier in 2006 compared to 1991.

111
Q

15) What is the light hypothesis of early puberty?

A

b) Light at night allows young girls to produce more hormones.

112
Q

16) What’s the problem with the light hypothesis?

A

a) Denmark has had lights on at night for longer than the period between 1991 and 2006, but the age of puberty changed hadn’t changed until 1991.

113
Q

17) What is the divorce hypothesis of early puberty?

A

d) Girls without fathers develop earlier.

114
Q

18) Describe the drawback of the divorce hypothesis?

A

c) Families are more stable in 2006 than in 1991, but the age of puberty onset has decreased.

115
Q

19) Describe the media hypothesis of early puberty?

A

c) Watching TV makes girls sexier.

116
Q

20) What evidence weakens the media hypothesis?

A

d) The amount of estrogen in girls’ bloodstream hasn’t changed.

117
Q

21) Describe Aksglaede’s hypothesis?

A

a) Girls are exposed to hormone-mimicking chemicals that cause early puberty.

118
Q

22) What evidence does Paul Kaplowitz offer that he believes weakens Aksglaede’s hypothesis?

A

c) If external estrogens were affect girls, you’d think you’d see early puberty in boys.

119
Q

23) How does Aksglaede counter Kaplowitz?

A

b) We do see earlier puberty onset in boys.

120
Q

24) During the 1980’s and 1990’s in Puerto Rico, toddlers experienced an epidemic. Describe it?

A

a) Early sexual development

121
Q

26) What are phthlatates?

A

a) A family of molecules used to stabilize scents
b) Endocrine disruptors
c) Substances added to plastics to make them more flexible
d) Substances found in most shampoos and lotions

122
Q

27) Did the author get her BPA level to zero with a little effort?

A

no

123
Q

28) Did the author get her triclosan level to zero with a little effort?

A

no

124
Q

29) What point does the chemical industry love to make?

A

a) The amount of chemicals released from any one thing is too small to be biologically important.

125
Q

30) Who had the highest breast-cancer rates after Hiroshima?

A

c) young girls

126
Q

31) What does BPA do to suppressor genes, and what does that mean for cancer?

A

c) BPA turns them off, making cancer more likely.

127
Q

32) What does BPA do to promoter genes, and what does that mean for cancer?

A

d) BPA turns them on, releasing cancer cells.

128
Q

33) Describe Jose Russo’s take-home message?

A

a) Don’t let young girls near endocrine disruptors.

129
Q

what is the name of the hypotheses that suggests that parasites and pathogens drive sexual reproduction

A

the red queen hypothesis

130
Q

within organisms that reproduce only sexually do you think that individuals might avoid mates with obvious parasite loads why

A

yes they are not healthy

131
Q

in nature what do scientists think symmetry indicates

A

high gene quality

132
Q

in human studies facial symmetry is found to be favored in two ways what are they

A

symmetry is attractive across individuals and cultures

133
Q

explain the rationale behind the idea that symmetry indicates genotypic quality

A

imperfect development is thought to cause deviations from symmetry

134
Q

sceintists think only _________ individuals can maintain ________ under enviornmental and genetic strain

A

high quality and symmetry

135
Q

does asymmetry significantly impact attractiveness

A

yes

136
Q

aside from developmental assault what causes deviations from symmetry

A

age

137
Q

besides symmetry what else predicts facial beauty

A

sexually demorphic facial cues

138
Q

what female facial features are consistently rated as beautiful

A

delicate jaw and small brows

139
Q

what male facial features are consistently rated as hot

A

large jaw and prominent brows

140
Q

what do males need to grow strong jaws and thick brows

A

testosterone

141
Q

why is testosterone expensive

A

metabolic energy and suppresses immune system

142
Q

what empirical evidence supports the idea that masculine traits indicate good genes

A

masculine faced men have lower incidence of disease and better medical health

143
Q

do individual women always prefer the same degree of symmetry and masculinity?

A

no

144
Q

three causes for vatiation across individual women

A

already has partner, thinks she is pretty, at peak fertility

145
Q

trade-off

A

situation that involves losing one quality in return for gaining access to something else

146
Q

three ways masculine faces make mens lives difficult

A

invest less in each partner, less likely to marry, perceived as poor quality parents

147
Q

what factors might influence whether a woman chooses good genes or high resources

A

enviornment

148
Q

enviornment has a lot of pathogens what kind of mate might a woman want

A

masculine to protect kids

149
Q

embodied capital

A

physical investment made in a person

150
Q

why do we reproduce sexually

A

to have kids

151
Q

first disadvantage of sex

A

diluted relatedness

152
Q

the theory of evolution through natural selection suggests_______________

A

organisms are evolved to maximize genetic representation in future generations

153
Q

which species gets more genes into the next generation: a snap dargon or an amoeba

A

amoeba

154
Q

what does sex do to genetic representation

A

cuts it in half

155
Q

what is the second big disadvantage of sex

A

males are a waste

156
Q

from an evolutionary perspective, why might scientists think males are a waste

A

cant reproduce by themselves, only contribute genes to offspring, cost mothers a lot of time and investment

157
Q

5 parasites

A

hookworm, filarial worm, round worm, tape worm, botfly

158
Q

who is likely to experience higher susceptibility to a parasite to which you are susceptible: your daughter or your clone?

A

clone

159
Q

what did alice and the red queen do to generate the red queen hypothisis

A

run fast but get nowhere

160
Q

until 2011 what kind of evidence provided sole support for the red queen hypothesis

A

field

161
Q

genetic recombination confers what benefit

A

mixes up alleles