Final Exam Flashcards
Surveillance for Infectious and Communicable Diseases
To gather the who, when, what, and where to determine why
Systematically collect, organize, and analyze data for a defined disease
Surveillance for agents of bioterrorism—anthrax, smallpox
List of Reportable Diseases- varies by state
National Notifiable Diseases- infectious and non-infectious
Populations at increased risk for transmission and infection
Children
Older adults
Immunosuppressed
High-risk lifestyles
Travelers
Health care workers
most probable cause of the increase in new emerging infectious diseases
Activities or behavior of humans, including changes in the environment
Emerging infections
Those in which the incidence has increased in the past two decades or has the potential to increase in the future
Airborne infections examples
Measles
Chicken pox
TB
Pertussis
Influenza
SARS
Foodborne infections
Salmonella
Hepatitis A
Trichinosis
E. Coli
Norovirus
Botulism
Mercury poisoning
waterborne infections
Cholera
Typhoid
Dysentery (diarrhea with blood or mucus)
Giardia
Hepatitis A
Most who die from this are small children
vector borne infections
West Nile
Lyme disease
Malaria
Rocky Mountain Spotted Fever
direct contact infections
mono
lice
scabies
STDs
Vaccine preventable diseases
Measles
Mumps
Rubella
Pertussis
Influenza
Polio
Tetanus
Incubation/latency period
time interval between invasion by infectious agent and symptoms
Prodromal period
here the pathogen continues to multiply, and the host begins to experience general signs and symptoms of illness
Too general to know what it is that’s making you sick
Period of illness
the signs and symptoms of disease are most obvious and severe
Period of decline
treatment or sickness passed
Replication stops, the number of pathogen particles begins to decrease, and the signs and symptoms of illness begin to decline
communicable period
time interval during which an infectious agent may be transferred directly or indirectly from an infected person
Can happen in any stage
Active immunity
Antibodies synthesized by the body in response to antigen stimulation
NATURAL active immunity
contact with an antigen through exposure
ARTIFICIAL active immunity
immunization with an antigen
Passive immunity
antibodies produced in one individual and transferred to another
NATURAL passive immunity
immunity from the placenta transferred from mother to child
ARTIFICIAL passive immunity
injection of serum from an immune human or animal i.e. , gamma globulin
Herd immunity
Type of immunity in which a large proportion of people in a population are not susceptible to a communicable disease, and the few susceptible people will not be likely to be exposed and contract the illness
Flu
Influenza is a viral respiratory infection
Transmission is airborne
Vaccines available!
Symptoms of flu
temp 100+
cough
sore throat
underlying condition that increases risk
Tuberculosis
Caused by Mycobacterium tuberculosis
Transmission is usually by airborne droplets from persons with TB
Negative pressure room!
symptoms of TB
cough, blood-tinged sputum, fatigue, Gradual weight loss, low-grade fever, nocturnal diaphoresis
critical period and meds times with TB
Critical period 6-12 months after infection
4-9 months meds with annoying side effects, compliance is key!
Treatment of TB
Targeted tuberculin testing and treatment of latent tuberculosis infection
Contributing factors for TB
Overcrowding
Poor ventilation
Poor health
HIV/AIDS
Poor diet
Homelessness
TB blood tests
also called interferon-gamma release assays or IGRAs
measures how the immune system reacts to the bacteria that cause TB
by testing the person’s blood in a laboratory
IGRAs
QuantiFERON®–TB Gold In-Tube test (QFT-GIT)
T-SPOT®.TB test (T-Spot)
Positive IGRA
means the person has been infected with TB bacteria. Additional tests are needed to determine if the person has a latent TB infection or active TB disease. A healthcare worker will then provide treatment as needed
Negative IGRA
means that the person’s blood did not react to the test and that latent TB infection or TB disease is not likely
Who are IGRAs the preferred method of testing for
People who have received bacille Calmette–Guérin (BCG). BCG is a vaccine for TB disease.
People who have a difficult time returning for a second appointment to look for a reaction to the TEST
TB skin test
Intradermal injection in the forearm- 0.1 ml PPD
Read reaction 48-72 hours after injection
Measure and record results in millimeters of induration
An induration of 5 or more mm is considered positive in
HIV-infected people
People who have had a recent contact with another person with TB
People with fibrotic changes on chest radiograph consistent with prior TB
Patients with organ transplants
People who are immunosuppressed for other reasons (like taking the equivalent of >15 mg/day of prednisone for 1 month or longer, taking TNF-α agonists)
An induration of 10 or more mm is considered positive in
Recent immigrants (<5 years) from high-prevalence countries
Injection drug users
Residents and employees of high-risk congregate settings
Mycobacteriology laboratory personnel
Persons with clinical conditions that place them at high risk
Children <4 years of age
Infants, children, and adolescents exposed to adults at high risk for developing active TB
An induration of 15 or more mm is considered positive in
Any person, including people with no known risk factors for TB. However, targeted skin testing programs should only be conducted among high-risk groups
Treatment and prevention of TB
Long-course anti-TB medication - can be up to 6-12 months on meds for active disease
DIRECTLY OBSERVED THERAPY
Healthcare professionals observe clients to ensure that they ingest each dose of anti-TB medication to maximize the likelihood of completion of therapy.
CDC recommends video DOT (vDOT) as an alternative to in-person DOT for people in TB treatment
Examples of diseases of travelers
Malaria
Foodborne and waterborne diseases
Diarrheal diseases
Yellow fever
Hepatitis
Chikungunya
Other endemic diseases
Zoonosis
an infection transmitted from a vertebrate animal to a human under natural conditions- rabies (hydrophobia)
Parasitic diseases
more prevalent in tropical climates and countries with inadequate prevention and control methods
What are nosocomial infections
in the hospital
People coming in and out of hospital are at risk
What is an Emerging Infectious Disease
Newly appearing in a population or community that hasn’t existed before
Measles
An acute viral respiratory illness.
VERY CONTAGIOUS
Lives on surfaces 2 hours
1 person can infect 9-10 people
S/S of measles
fever (as high as 105°F) and malaise,
the three “C”s: cough, coryza, and conjunctivitis
Koplik spots - inside the mouth on the cheeks
followed by a maculopapular rash
Rash – flat, red spots that can become raised
Koplik spots – whitish-blue spots on the inside of the cheeks–followed by maculopapular rash
Mumps
A highly contagious viral illness in young adults
Transmission: coughing, sneezing, kissing, sharing food or drinks
Need to spend 9 days in isolation
No treatment or cure
S/S of mumps
Flu-like symptoms followed by painful swelling of one or both glands in cheek near jaw line**
It can start as an earache or tenderness along the jaw
Usually last for 9 days
What can mumps lead to
Meningitis
Painful swollen testicles
Painful swelling of ovaries and breasts
Pancreatitis
Permanent deafness
Spontaneous abortions
Rubella
It is a contagious viral disease that can cause a mild illness to serious health problems
Contagious for about a week before and a week after the rash appears
Transmission: coughing, sneezing, or touching contaminated surfaces
S/S of rubella
Mild fever
Headache
Sore throat
Red rash
Swollen lymph nodes.
The rash usually starts on the face and spreads to the rest of the body. About half of people who get rubella don’t develop a rash
Complications of rubella
If a pregnant woman gets rubella, she has a 90% chance of passing it to her fetus
Treatment of rubella
Usually resolves on own
Pain medications
Vaccination
pertussis
A bacterial infection that causes severe coughing fits and can be life-threatening for babies.
Spreads easily through coughing or sneezing
Babies may not cough much, or they may not cough at all. Instead, they may have apnea
If people are visiting newborn babies, make sure they’re vaccinated!
Treatment of whooping cough
Antibiotics
Rest, fluids, and avoid cigarette smoke
Vaccine
Polio (poliomyelitis)
A highly contagious viral disease that can cause paralysis and death.
Due to vaccination programs, it has been eliminated in many areas
Common S/S of polio
Fever
Headache
Fatigue
Vomiting
Muscle pain
In more severe cases, polio can cause paralysis, affecting the arms, legs, or both. Paralysis can occur within hours of infection and is usually permanent
Can cause respiratory failure and death
Transmission of polio
Person-to-person contact with infected feces, contaminated food or water, or through respiratory droplets from an infected person
Treatment of polio
No cure
Bed rest, pain relievers, muscle relaxers, and physical therapy
Tetanus
Bacterial
S/S of tetanus
Muscle spasms in the jaw, face, throat, chest, neck, back, abdomen, and buttocks
Fever
Trouble swallowing
Rapid heart rate
Incontinence
Treatment of tetanus
Focused on managing complications
Vaccination
Hepatitis
Viral hepatitis refers to a group of infections that primarily affect the liver. These infections have similar clinical presentations but different causes and characteristics
Hep A
It may last several weeks and can be debilitating, but most people recover
Affects the liver–jaundice, clay colored stools, dark urine
Vaccine preventable!!
Hep A route and transmission
Spread through fecal-oral route (when fecal matter enters the mouth)
Direct contact
Food and beverages
Cups and spoons
Objects handled by an infected person
Hep A S/S
N/V/D, stomach pain, anorexia, fever, fatigue, jaundice
Prevention of hep A
Hand hygiene education
Keeping toilets and bathrooms clean
Avoiding infected water sources
Peeling fruits and vegetables, and avoiding undercooked meat and fish
Drink bottled water or boil tap water before drinking
People at high risk of hep A
Daycare workers
People traveling to countries with high rates
IV drug users
homosexual men
anybody with chronic liver disease
Hep B
More self limited
Bigger ability to infect compared to HIV because it stays outside the body for longer
Vaccine-preventable
OSHA mandate requires healthcare workers to be offered scene at the expense of their employer
Hep B route and transmission
Spread through blood and body fluids
Hep B people at risk
IV drug users
immigrants
refugees
healthcare workers
hemodialysis patients
prisoners
persons with STDs
Hep B acute vs chronic
Acute: Will develop antibodies and rid the body of the virus on its own. You will have lifelong immunity to acute hep b
Chronic: Mostly seen in immunodeficiency, can’t rid self of virus so they will remain lifelong carriers. Can lead to hepatic carcinoma and chronic active hepatitis
Hep C and spread
Most common chronic blood-borne infection in the US
The leading cause of chronic liver disease, end-stage liver disease, liver cancer, and liver transplants. Very serious!
Spread through blood or body fluids
High risk of Hep C
healthcare workers
infants born to infected moms
IV drug users
persons with multiple sex partners
risk factors for STDs
younger than 25
minority
urban setting
poverty
using crack cocaine
older adults
Gonorrhea
Gram negative, goes for mucus membranes, affects anus, GU tract/genitals, pharynx
Can be spread from mother to child
Increased risk for PID in women
S/S of gonorrhea
Maybe no symptoms!
Abdominal pain or pain with intercourse
Vaginal discharge and bleeding
Infected kidneys
UTI (dysuria)
Burning sensation with urination
Inflammation of the penile
Swollen testicles
Green discharge from the penis
Syphilis
Risk is increasing
Babies can get this and die a lot from it
Stage 1 syphilis
Sore on entry site/chankra
Starts macular, will grow and ulcerate to create indented sore on back
30-90 days after exposure
Will go away into 3-6 weeks or continue into stage 2
Stage 2 syphilis
Body rash that starts on palms of hands and soles of feet, moves inward to trunk
Sore throat, fever, and swollen lymph nodes
4-10 weeks after initial infection
Stage 3 syphilis
Rare because of antibiotics
Affects internal organs
Can lead to blindness, psychosis, and cardiovascular damage
Can lead to death of babies, blindness, deafness, or premature birth
Meningitis, anemia, low birth weight, and death in babies born
3-15 years after initial infection
Chlamydia
The most common reportable STD in the US
About 70-80% of women with chlamydia don’t notice any symptoms
Cervix, rectum, or throat in women
Urethra, rectum, or throat in men
Treated with antibiotics
Exposure again can make you get it again
S/S of chlamydia
usually appear 1-3 weeks after exposure
Pain when urinating
Discharge
Urinary frequency
Pain in the lower abdomen
Pain in the testicles
Fever, nausea
Painful intercourse
Herpes
Can be passed in childbirth
Painful, no cure (chronic, has latency periods of dormancy and reactivation)
Linked to cervical cancer, spontaneous abortions, and high risk of transmission to newborns
Prodromal period before outbreak
Herpes treatment
Antiviral medications include acyclovir, famciclovir, and valacyclovir.
The World Health Organization (WHO) recommends starting treatment within the first three days of an initial outbreak
HPV
Genital warts found on shaft of penis or vulva/vagina/cervix and around anus
Viral infection
Caused by only a few of the 100+ strains of HPV
Transmitted by skin/skin contact in genital area
Treatable
Visual test
Common in young, sexually active women
Can cause cancer
Vaccine preventable
S/S of HPV
Genital warts
Cervical cancer
precancerous lesions
lesions of upper respiratory tract
Plantar warts
Usually no manifestations, they can be dormant and activate when there is a drop in immunity
Genital warts in HPV
Usually soft, fleshy, and moist. They may ooze, bleed, get pustular and itch, at times
In women, they can be seen on the labia majora, minora, cervix, vagina, and anus
In men, they mostly appear on the scrotum or penis