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Infectious disease drug cards > Final exam > Flashcards

Final exam Flashcards

1
Q

Azithromycin brand name

A

Zithromax, Z-pak

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1
Q

Azithromycin class

A

Macrolide antibiotic

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2
Q

Azithromycin dosage form

A

tablet and powder for oral suspension

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3
Q

Azithromycin on-label

A

Acute infective exacerbation of COPD, skin or tissue infection; Bacterial sinusitis; Chancroid, nongonococcal cervicitis; Community-acquired pneumonia; Sexually transmitted infections; Streptococcal pharyngitis

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4
Q

Azithromycin off-label

A

Traveler’s dirrhea

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5
Q

Azithromycin BBW

A

None

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6
Q

Azithromycin CI

A

Hypersensitivity to macrolides or ketolide antibiotic

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7
Q

Azithromycin adverse effects

A

Diarrhea, nausea, vomiting

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8
Q

Clarithromycin brand name

A

Biaxin

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9
Q

Clarithromycin class

A

Macrolide antibiotic

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10
Q

Clarithromycin dosage form

A

tablet, suspension and ER

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11
Q

Clarithromycin on-label

A

Acute infective exacerbation of bronchitis; Community-acquired pneumonia; Disseminated infection due to M . avium-intracellulare; H. pylori GI tract infection; Streptococcal pharyngitis-group A; COPD, acute exacerbation

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12
Q

Clarithromycin off-label

A

Bacterial endocarditis prevention for high risk patients

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13
Q

Clarithromycin BBW

A

None

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14
Q

Clarithromycin CI

A

Hypersensitivity to any macrolide or ketolide antibiotic; concomitant colchicine, cisapride, pimozide, astemizole, terfenadine, ergotamine, dihydroergotamine, or HMG-CoA reductase inhibitors metabolized by CYP3A4/5, history of cholestatic jaundice/hepatic dysfunction with use of clarithromycin, colchicine in renal or hepatic impairment

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15
Q

Clarithromycin adverse effects

A

taste disturbance

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16
Q

Erythromycin brand name

A

Erythrocin

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17
Q

Erythromycin class

A

Macrolide antibiotic

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18
Q

Erythromycin dosage form

A

capsule, tablet (DR), suspension

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19
Q

Erythromycin on-label

A

Bacterial infection

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20
Q

Erythromycin off-label

A

Chlamydia trachoma’s infections, uncomplicated; Nongonococcal urethritis

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21
Q

Erythromycin BBW

A

None

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22
Q

Erythromycin CI

A

Concurrent use with ergotamine, terfenadine, astemizole, lovastatin, simvastatin, cisapride

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23
Q

Erythromycin adverse effects

A

Diarrhea

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24
Q

Doxycycline brand name

A

Vibramycin, Doxy 100

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25
Q

Doxycycline class

A

Tetracycline antibiotic

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26
Q

Doxycycline dosage form

A

powder for oral suspension, tablet, capsule, syrup

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27
Q

Doxycycline on-label

A

Acinetobacter infection; Acne vulgaris; Gonorrhea, uncomplicated; Staphylococcal infection of skin; Pneumonia, community-acquired

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28
Q

Doxycycline off-label

A

Lyme disease prevention; Prosthetic joint infection; Otitis media, acute; Cellulitis, mild to moderate

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29
Q

Doxycycline BBW

A

None

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30
Q

Doxycycline CI

A

Hypersensitivity, concurrent retinoic acid derivatives

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31
Q

Doxycycline adverse effects

A

Esophageal injury; Photosensitivity, skin hyperpigmentation, tooth discoloration in children <8 yo

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32
Q

Minocycline brand name

A

Minocin

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33
Q

Minocycline class

A

Tetracycline antibiotic

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34
Q

Minocycline dosage form

A

tablet, capsule

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35
Q

Minocycline on-label

A

Acne vulgaris; allergy to penicillin-bacterial infectious disease

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36
Q

Minocycline off-label

A

None

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37
Q

Minocycline BBW

A

none

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38
Q

Minocycline CI

A

hypersensitivity

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39
Q

Minocycline adverse effects

A

dizziness and vertigo, tooth discoloration in children <8 yo, headache

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40
Q

Clindamycin oral brand name

A

Cleocin

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41
Q

Clindamycin class

A

Lincosamide antibiotic

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42
Q

Clindamycin dosage form

A

capsule, granules for oral solution

43
Q

Clindamycin oral, on-label

A

Bacterial infectious disease (streptococci; staphylococci; pneumococci); Infection of skin; Infectious disease of abdomen; Lower respiratory tract infection; Pelvic inflammatory disease; Septicemia; Osteomyelitis; Diabetic foot infection

44
Q

Clindamycin off-label

A

Bacterial vaginosis; Streptococcal pharyngitis, penicillin-allergic patients; Prosthetic joint infections

45
Q

Clindamycin oral BBW

A

Colitis

46
Q

Clindamycin oral CI

A

Hypersensitivity

47
Q

Clindamycin oral adverse effects

A

Nausea

48
Q

Albendazole brand name

A

Albenza

49
Q

Albendazole class

A

Antihelmintic

50
Q

Albendazole dosage form

A

tablet

51
Q

Albendazole on-label

A

Parenchymal neurocysticercosis caused by Taenia solium

52
Q

Albendazole off-label

A

Ancylostoma caninum (round and hookworm); Enterobius vernicularis (pinworm); Giardiasis; Chinese liver fluke worm; Cutaneous larva migrans; Gnathostomiasis and microsporidiosis; Oesophagostomum bifurcum; Toxocariasis; Trichinellosis

53
Q

Albendazole BBW

A

None

54
Q

Albendazole CI

A

Hypersensitivity to albendazole or benzimidazole

55
Q

Albendazole adverse effects

A

Headache, elevated LFTs

56
Q

Acyclovir brand name

A

Zovirax

57
Q

Acyclovir class

A

Viral DNA polymerase inhibitor

58
Q

Acyclovir dosage form

A

capsule, tablet, suspension

59
Q

Acyclovir on-label

A

Genital herpes simplex, herpes zoster (shingles), varicella (chickenpox); cold sores

60
Q

Acyclovir off-label

A

Herpes simplex prevention in immunocompromised patients

61
Q

Acyclovir BBW and CI

A

None and Hypersensitivity

62
Q

Acyclovir adverse effects

A

Malaise

63
Q

Valacyclovir brand name

A

Valtrex

64
Q

Valacyclovir class

A

viral DNA polymerase inhibitor

65
Q

Valacyclovir dosage form

A

tablet

66
Q

Valacyclovir on-label

A

Genital herpes simplex; herpes zoster (shingles); varicella; herpes labials (cold sores)

67
Q

Valacyclovir off-label

A

CMV prevention in allogeneic stem cell transplant; herpes simplex or varicella zoster in cancer patients; bell palsy, new onset, adjunctive therapy

68
Q

Valacyclovir BBW and off-label

A

None and hypersensitivity

69
Q

Valacyclovir adverse effects

A

Malaise, headache, nausea, neutropenia, nasopharyngitis, increased LFTs

70
Q

Atazanavir brand name

A

Reyataz

71
Q

Atazanavir class

A

antiretroviral agent, protease inhibitor

72
Q

Atazanavir dosage form

A

capsule and powder

73
Q

Atazanavir on-label

A

Treatment of HIV-1 in naive patients, patients with prior virologic failure and pregnant patients

74
Q

Atazanavir off-label

A

none

75
Q

Atazanavir BBW and CI

A

None and hypersensitivity

76
Q

Atazanavir adverse effects

A

Rash, hyperlipidemia, elevated LFTs, abdominal pain, elevated bilirubin level, cough, fever

77
Q

Efavirenz brand name

A

Sustiva

78
Q

Efavirenz class

A

antiretroviral agent, reverse transcriptase inhibitor

79
Q

Efavirenz dosage form

A

capsule and tablet

80
Q

Efavirenz on-label

A

Treatment of HIV-1 infection

81
Q

Efavirenz off-label

A

none

82
Q

No BBW for Efavirenz; CI are?

A

Hypersensitivity or concurrent use of bepridil, cisapride, elbasvir, grazoprevir, midazolam, pimozide, triazolam, St. John’s wort, or ergot alkaloid

83
Q

Efavirenz adverse effects

A

Anxiety, dizziness, insomnia, headaches, rash, nausea, vomiting, diarrhea, hyperlipidemia

84
Q

Emtricitabine/Tenofovir Disoproxil brand name

A

Truvada

85
Q

Emtricitabine/Tenofovir Disoproxil clas

A

antiretroviral agent, reverse transcriptase inhibitor

86
Q

Emtricitabine/Tenofovir Disoproxil dosage form

A

tablet

87
Q

Emtricitabine/Tenofovir Disoproxil on-label

A

treatment of HIV-1 infection in combination with other antiretrovirals; preexposure prevention of HIV-1

88
Q

Emtricitabine/Tenofovir Disoproxil off-label

A

Treatment of hepatitis B; Postexposure prevention for HIV-1

89
Q

Emtricitabine/Tenofovir Disoproxil BBW

A

Hepatitis B exacerbation, lactic acidosis, drug resistance with preexposure prophylaxis

90
Q

Emtricitabine/Tenofovir Disoproxil CI

A

Do not use for preexposure prophylaxis in patients with unknown or HIV-1 positive status. Only for use in combination with other antiretrovirals

91
Q

Emtricitabine/Tenofovir Disoproxil adverse effects

A

Hyperpigmentation, rash, hypophosphatemia, nausea, diarrhea, abdominal pain, weakness, cough, rhinitis, dizziness, headache, insomnia, fatigue, decreased bone mineral density

92
Q

Maraviroc brand name

A

Selzentry

93
Q

Maraviroc class

A

antiretroviral agent; CCR5 antagonist

94
Q

Maraviroc dosage form

A

tablet and solution

95
Q

Maraviroc on-label

A

treatment of CCR5-tropic HIV-1 infection

96
Q

Maraviroc off-label

A

none

97
Q

Maraviroc BBW

A

Hepatotoxicity, severe rash, allergic reaction

98
Q

Maraviroc CI

A

Patients with CrCl <30 mL/min or ESRD who are taking potent CYP3A4/5 inhibitors or inducers

99
Q

Maraviroc adverse effects

A

Fever, rash, URI, cough, vomiting

100
Q

Raltegravir brand name

A

Isentress

101
Q

Raltegravir class

A

antiretroviral agent, integrase inhibitor

102
Q

Raltegravir dosage form

A

tablet; chewable tablets; oral packet

103
Q

Raltegravir on-label

A

Treatment of HIV-1 infections

104
Q

Raltegravir off-label

A

Occupational and nonoccupational HIV postexposure prevention

105
Q

Raltegravir BBW and CI

A

None and Hypersensitivity

106
Q

Raltegravir adverse effects

A

Elevated LFTs

Infectious disease drug cards (4 decks)

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