FINAL - exam 1 and 2 Flashcards
Highly protein bound drug (%)
89%
Low protein bound drug (%)
30%
2 high protein bound drugs lead to
Toxicity
Hypoalbuminemia puts you at risk for
Toxicity
Trough
Time of LOWEST plasma drug concentration
-Shows RATE OF EXCRETION, helps understand kidney function
When do you draw trough?
Right before the next dose
Acute Asthma Attack Management drugs (5)
Sympathomimetics - Epinephrine (Adrenalin)
Selective Beta 2 Receptor Agonists - Albuterol (Proventil)
Steroids - Dexamethasone IV, Hydrocortisone IV
Bronchodilators
Albuterol
- classification + mechanism
- onset
- duration
- side effects
Selective Beta-2 Receptor AGONIST - works directly with beta 2 receptors in the bronchi to cause BRONCHODILATION , opening upt the airway
- Rapid onset
- Long duration
- Few side effects
Systemic effects of Selective Beta-2 Receptor Agonists
Increased BP, increased HR, decreased GI motility and tone
Steroids for Acute Asthma Attack
Promote smooth muscle relaxation through beta adrenergic receptor activity, decrease swelling, promote anti-inflammation
Bronchodilator assessment
Assess RR, use of accessory muscles, JVD, edema
Bronchodilator intervention
Teach patient on peak flow meter
Annual flu shot
Pneumonia vaccine x 5 years
Bronchodilator evaluation
Assess peak flow readings, breath sounds, O2 sat, color, ability to perform ADLs
Diuretic categories for emergencies (4)
Thiazide diuretics - Hydrochlorothiazide (HCTZ)
Loop Diuretics - Furosemide (Lasix)
Potassium Sparing - Spirnolactone (Aldactone)
Osmotic Diuretics - Mannitol (Osmitrol)
Primary line of therapy for patients with HF
Diuretics
