Final Flashcards
Function of the Medial Longitudinal Fasciculus (MLF)
The function of the MLF is to coordinate bilateral eye movement and eye/head movement.
It also coordinates all the LMN across the 3 nuclear groups: Oculomotor, Trochlear and Abducens.
Cranial Nerve III
Superior Rectus Medial Rectus Inferior Rectus Inferior Oblique Levator Palpabrae
Cranial Nerve IV
Superior Oblique
Cranial Nerve VI
Lateral Rectus
Superior Oblique Action
Looking down and medial
Inferior Oblique Action
Looking upward and medial
Deep Cerebellar Nuclei (DCL)
Dentate Nucleus
Interposed Nucleus
Fastigial Nucleus
Medial Vestibulospinal Tract
Responsible for head relative to eye position.
Descending: Inferior and Medial Vestibular Nuclei.
Travels in bilateral MLF
Lateral Vestibulospinal Tract
Controls posture and balance.
Goes all the way down to the Lumbosacral spinal cord.
Does not travel in the MLF rather lateral tegmentum?
Striatum
Caudate Nucleus
Putamen
Nucleus Accumbuns
Lenticular Nuclei
Globus Palladum (E and I) Putamen
Glutamate
Excitatory +
GABA
Inhibitory -
Dopamine
Excitatory + OR Inhibitory -
Acetylcholine
Excitatory +
Corticostriatal Pathways + or -
Allcortical inputs to the BG are glutamatergic (+)
What NT do striatal neurons project to the external and internal globus pallidus?
GABAergic (-)
What NT do the Globus pallidus and substantial nigra pars reticulata neruons project to the VL thalamas
GABAergic (-)
Subthalamic neurons projecting tothe globus pallidus internal project what type of NT?
Glutamatergic (+)
Basal Ganglia Outpt Circuits
GPi and SNpr are the basal ganglia output cicuits.
Their axons project to the VA/VL Thalamas (Gpi) and superior colliculus (SNpr).
Input to the Basal Ganglia
Corticostriatal Pathways from coritcal inputs from M1 and Premotor cortex.
All inputs feed into the BG cia the striatum (Caudate and Putamen)
Nigrostriatal Pathways also projects to teh striatum to modulate the corticostriatal inputs.