Final Flashcards
Pathogens are not acclimated with which types of flora?
Transient flora, although this flora may cause disease at other locations after its short rout through the mouth.
When do biofilm first form?
When the first teeth erupt.
Strep. sanguinis is…
a pioneer species in tooth plaque development.
When does strep. mutans, first manifest?
typically first appear in large numbers when the pits & fissures of the second molar emerge at about 2-years.
The three bugs responsible for most caries
S. mutans
lactobacillus
Actinomyces
What subs for Ca^2+ in Hydroxyapatite
Ss2+
Mg^2+
What subs for OH in Hydroxyapatite
F-
Cl-
What subs for PO4^3- in Hydroxyapatite, What might be a problem?
CO3^2- (above 3% sub is bad, less resistance to acid)
Xerostomia is most often caused by…
Drugs, side effects
Junctional epithelial cells display…
HLA class II and therefore can present extracellular antigenic peptides, thereby activating Th cells.
Junctional epithelial cells, if stimulated by certain microbial products,
release large amounts of…
chemokine IL-8 and numerous other
cytokines and chemokines that can activate and stimulate local capillaries,
mast cells, and are chemotactic for PMNs.
Supragingival plaque biofilm is primarily made of..
facultative and microaerophilic bacteria
