Final Flashcards
Patient is a heavy smoker, symptoms worse at waking up, high pollution, and cold weather, he had pneumonia multiple times, hyperinflated chest
COPD
Obstructive lung diseases
Chronic bronchitis Bronchiolitis Asthma Broncheiectasis Emphysema (permanent destructive enlargement of airspaces)
What paraclinical investigations would you request for COPD? What would you expect to find?
CXR - hyperinflation, flattened diaphragm, hyperlucent lungs
Arterial blood gas - CO2 retention (in severe cases)
ECG
Lung function test (FEV1 and FVC < 70%)
COPD
Progressive, non-reversible airflow obstruction which does not change markedly over several months
Emphysema
Walls of alveoli are destroyed and lose elasticity, hindering the outflow of air when a person exhales
Risk factors of COPD
Smoking, occupation, male, pollution
Management of COPD
Smoking cessation
Brochodilators and corticosteroids
Home oxygen therapy in severe cases
Vaccination against pneumonia and flu
Asthma
Chronic inflammatory disorder with episodic, reversible airway obstruction and increased airway responsiveness
Increased number of mucus gland cells, infiltration of immune cells, dilation of blood vessels
Risk factors for asthma
Multifactorial
Immune system (ie in response to allergens) for early-onset
Drugs (beta blockers, aspirin, antibiotics)
Infection
Smoking during pregnancy
Clinical presentation of asthma
Wheezing, dyspnea, cough, chest tightness
Diagnosis of asthma
15% improvement in FEV1 or PEF following bronchodilator use
15% improvement during 1 week home monitoring
Management of asthma
Acute attack - give oxygen, beta2 agonists, systemic corticosteroids, maybe mechanical ventilation
Chronic - patient education, self-monitoring, avoidance of triggers, drug treatments (relieve w/ b2 agonists, anti-cholinergs or prevent with corticosteroids)
7 common respiratory symptoms
Dyspnea (breathlessness) High respiratory rate (>12-20) Cough (dry/productive) Hemoptysis Chest pain Wheeze Stridor
Wheezing
Wheezing is expiratory due to obstruction of small peripheral airways
Stridor
Stidor is inspiration due to obstruction of central airways
Crackles
Crackles are the popping sound of alveoli when they have fluid, mucus
Paraclinical investigations for respiratory conditions
CXR Sputum examination Blood tests Pulse oximetry Arterial blood gas analysis Spirometry and peak expiratory flow (PEF)
Inspection in pneumonia
General discomfort, use of accessory respiratory muscles, skin color, respiratory rate
Auscultation in pneumonia
Consolidation, crackles
Investigations for pneumonia
CXR Blood tests (WBC for infection) Temperature (elevated due to infection) Blood, sputum culture Arterial blood gases
Clinical features of pneumonia
Fever, breathlessness, cough with purulent sputum, rigor/malaise/anorexia, confusion in elders
Risk factors for pneumonia
Smoking (kills cilia), alcohol, corticosteroids (inhibit immune system), age (<2 or >65), comorbidities (asthma, COPD, heart failure)
Severity of pneumonia
Respiratory rate >30 Diastolic BP <60 mm Hg S-urea >7 mM Confusion 2+ of these is a 36-fold increase in mortality
Management of pneumonia
Supportive therapy (oxygen, fluids)
Antibiotics (broad spectrum, more specific after sensitivity test)
Lung physiotherapy
Complications of pneumonia
Respiratory failure (change antibiotics, consider respirator) Spreading to other organs (pericarditis, endocarditis, meningitis, arthritis)
Hemoptysis
Coughing up blood in sputum
Causes of hemoptysis
TB, pneumonia, bronchial/lung cancer, lung embolism, exacerbation of COPD