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Toxicology > Final > Flashcards

Final Flashcards

1
Q

initial effect of inhaling CO

A

HA

confusion

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2
Q

chronic use of steroidal anti-inflammatory medications will cause what effects

A

ulcers
hyperglycemia
cataracts

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3
Q

what oxidizes Hb to form Methemoglobin

A

nitrous oxide

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4
Q

asprin should not be used to manage s/s of what

A

Gouty arthritis

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5
Q

Chronic use of steroidal anti-inflammatory Rx can cause GI ulcers because of inhibition of what enzymes

A

phospholipase A2

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6
Q

CO inhilation will do what

A

reduce amt Hb avail to transport O2
misdx as flu
cause fatal damage

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7
Q

Air pollutants cause what

A

pulmonary edema

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8
Q

prevention of phospholipase A2 does what

A

prevents formation of arachidonic acid

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9
Q

characteristic squale of dermal contact with strong acid

A

superfical damage with eschar formation

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10
Q

hypertensive crisis is serious advers interaction involving what substance

A

monoamine oxidase inhibitors

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11
Q

delayed onset pulmonary tox is char of which chem exposure

A

inhalation of irritant gas with low water solubility

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12
Q

methemoglobinemia is characterized by

A

caused by exposure to oxidizing chemicals

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13
Q

person using corticosteroids for osteroarthritis over chronic duration will have hyperglycemia dt

A

stimulation of gluconeogenesis

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14
Q

exposure to organophosphate insecticide (acetylocholinesterase inhib) will cause which effects

A

increase exocrine secretions

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15
Q

CO has greatest binding affinity for which form of Hb

A

fetal

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16
Q

Had hatter disease is consequence of chronic exposure to which toxic chemical

A

Mercury

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17
Q

risk for parkinsons disease and angina is increased upon exposure to which chem

A

CO

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18
Q

Daily use of low doses of asprin is perscribed to pt to prevent intravascular clotting after cardio sx. theraputic dose to manage px, fever, inflammation is 6x this dose. rationale for low dose is

A

inhibit thomboxane synth

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19
Q

cheyne-stokes respiration caused by fluctuations in PCO2 lvls. effect of what

A

narcotic analgesic overdose

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20
Q

chronic use of what therapeutic agent most likely increase risk for fracture and osteoporosis

A

proton pump inhibitor

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21
Q

dental anesthetic NO must be combo with O2 to prevent

A

methemoglobulinemia

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22
Q

CO causes

A

HA
hypoxia
bright venous blood

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23
Q

highly soluble irritant gases pose highest risk to what patients

A

those with asthma

24
Q

confirmation of CO poisoning

A

carboxyhemoglobin blood levels

25
Q

toxic chem that has a sweet taste

A

Lead acetate

26
Q

what category chemical will cause liquefactive necorsis

A

strong base

27
Q

excessive consumtion of what food will increase risk for mercury poisoning

A

fish/tuna

28
Q

metallic poison that causes psychosis

A

lead

29
Q

non steroidal anti-iflam rx provide palliative relief by inhib what enxymes

A

cyclo-oxygenase

30
Q

acute overdose with aspirin can cause hyperthermia why

A

asprin uncouples oxidative phos

31
Q

low dose use of aspirin on a chronic basis can increase risk for GI ulcers

A

aspirin inhib COX 1 in gastric mucosa

32
Q

what are anti-iflammatory steroids

A

cortisol
prednisone
dexamethasone

33
Q

overuse of what anti-inflam rx will not cause s/s cushings

A

aspirin

34
Q

what aggrivates gouty arth

A

aspirin

35
Q

reyes syndrome is associated with management of viral fevers in children with what antipyretic agent

A

aspirin

36
Q

narcotic analgesic agents will cause what effects

A

suppress coughing
stim vomit
CNS depression

37
Q

pinpoint pupil is characteristic of what

A

narcotics

38
Q

50yo pt active peptic ulcer takes recomended analgesic to manage pain complain lack energy . lab data anemic and prolonged bleeding time. what is the cause

A

aspirin

39
Q

exposure to cyanide can cause death as a result of which

A

inhibition of cytochrome oxidase (block ATP synth)

40
Q

pt with asthma exitis moon face, buffalo hump and mild hyperglycemia what rx are they taking

A

dexamethasone

41
Q

acute OD produces centrilobar hepatic necrosis

A

tylenol

42
Q

chocolate cyanosis is associated with

A

methmeglobinemia

43
Q

what chemical causes coagulative necrosis

A

strong acid

44
Q

first indicator of methemoglobulinemia

A

cyanosis

45
Q

rish for angina increase with exposure to

A

CO

46
Q

exposure to what chemicals will cause chocolate cyanosis

A

nitrates
nitrites
chlorates

47
Q

well water in midwest may cause hypoxia because of high concentration of

A

nitrates and nitrites

48
Q

cherry red cyanosis is associated with

A

CO poisoning

49
Q

allergic rxn to aspirin caused by increase production of

A

leukitrienes

50
Q

forms carbamino-Hb

A

CO2

51
Q

pulmonary infarct

A

ground level ozone

52
Q

inhib cytochrome oxidase

A

cyanida

53
Q

forms carboxy hemoglobin

A

CO

54
Q

asphyxiant

A

hydrogen sulfide

55
Q

assoicated with reyes syndrome

A

aspirin

56
Q

cause hyerpglycemia through glycogenolysis

A

epinephrine

57
Q

stimulates gluconeogenesis

A

prednisone

Toxicology (3 decks)

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