Final Flashcards
What is classical presentation for ringworm in horses?
alopecia around periocular, face, girth area
What horse derm dz causes severe pruritis, happens in winter, and causes alopecia on the mane and neck?
pediculosis (lice)
What horse derm dz happens in the summer, is progressive and causes rat tail?
culicoides
What horse derm dz causes extreme pruritis, happens in the summer, and occurs in horses greater than 4 years old?
onchocerciasis
What horse derm dz causes paintbrush scabs along dorsum and occurs in fall and winter?
dermatophilosis
What is the only pemphigus dz that affects horses?
pemphigus foliaceus
What hypersensitivity type is caused by sensitized T lymphocytes and is involved in allergic contact dermatitis?
Type 4
What do most treatments for atopic dermatitis act on?
TH2 cells
What do animals with atopy have increased numbers of?
langerhan cells, T helper 2 cells, cytokines
What is the MOA of cyclosporine?
inhibits cytokine release, inhibits langerhan cells, inhibits histamine
What drug can be given with cyclosporine to decrease the dose?
ketoconazole
What is the difference between atopy and contact dermatitis?
atopy: type 1-4, typically 1
contact: type 4
What are the treatment options for feline plasma cell pdododermatitis?
doxycycline, cyclosporine, chrysotherapy
What type of hypersensitivity is food allergies?
type 1-3, can be immediate or delayed
What is the disease that causes vesicles and urticarial plaques in response to drug reactions in small animals?
erythema multiforme
What is the name of the disease that is a serious drug reaction and results in large areas of skin to necrose and slough?
toxic epidermal necrolysis
WHat drugs can cause erythema multiforme?
cephalexin, chloramphenicol, gentimicin, thyroxine, TMS, penicillin, aurothioglucose, diethylcarbamazine
What lesions are present in subcorneal pustular dermatosis?
nonfolicular pustules that are transient, may be pruritic
What is the treatment for subcorneal pustular dermatosis?
sulfonamides
What breed is predisposed to panniculitis?
dachsunds
What is the treatment for panniculitis?
tocopherol (Vit E), pentoxiphyline, steroids, tetra
Term for sudden hair loss immediately after severe illness or chemotherapy?
anagen defluxion
Term for massive shedding due to stressful event.
telogen defluxion
What underlying diseases are associated with metabolic epidermal necrosis?
hepatic disease (DM, glucagon tumor, cushings)
What causes the lesions associated with metabolic epidermal necrosis?
hypoaminoacidemia or high glucagon
What is the characteristic histopathological lesion associated with metabolic epidermal necrosis?
french flag lesion - red white and blue