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Immunology > Final > Flashcards

Final Flashcards

1
Q

Mechanism/s for cell damage in type II hypersensitivity

A

All of the above

classical complement cascade, natural killer cells, opsonization

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2
Q

incompatible blood transfusion could induce a hemolytic reaction that results in intravascular lysis of the rbc’s, and release of _____ from lysed cells.

A

hemoglobulin

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3
Q

the lack of immune response for self -antigens in the tissue is caused by:

A

A and B

deletion of self reactive cells, inactivating the cell (anergy)

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4
Q

T/F function of T suppressor cells is important in suppression

A

true

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5
Q

antibodies against antibodies called _____

A

anti-idiotype antibody

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6
Q

T/F in graves disease antibodies in the blood, the TSH (thyroid stimulating hormone) receptors on the thyroid gland

A

true

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7
Q

which of the following autoimmune disease is associated with butterfly rash on the face?

A

systemic lupus

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8
Q

which of the following factors is/are involved in insulin dependent diabetes mellitus autoimmune disease?

A

A and B

infection, HLA gene

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9
Q

which one of the following biochemical/s is/are going to be reduced in hashimoto’s thyroiditis?

A

thyroxin

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10
Q

which of the following is called rheumatoid factor?

A

IgM-antibody against F-c portion of a patients own IgG

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11
Q

autoantibodies in double-stranded DNA are typical findings in which of the following disorders?

A

Systemic Lupus erythematosus

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12
Q

multiple sclerosis is associated with which of the following types of hypersensistivity reactions?

A

IV and III

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13
Q

the antibodies in warm agglutinin type immune hemolytic anemia consist of which of the following classes of immunoglobulins?

A

IgG

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14
Q

allografts of lymphoid tissue are particularly immunogenic because of the high content of

A

MHC class II expressing cells

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15
Q

An example of a type III immune complex disease is

A

Rheumatoid arthritis and (SLE) Scleroderma

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16
Q

the localized reactions to infected antigens in the same body site such as booster shot are called

A

Arthus reaction

17
Q

a positive tuberculin skin test is an example of

A

a delayed type allergy

18
Q

contac dermatitis is causes by

A

chemical absorbed by the skin

19
Q

a graft transplanted between individualS That are members of different species

A

xenograft
(allographt same species
autograft same individual
isograft (syngraft) genetically identical. same species, i.e. twins)

20
Q

factors that affecting the immune system and decrease the immune functions are as follow

A

A and C

  • chronic disease
  • emotional stress
21
Q

T/F patient with severe immunodeficiency disease in both T- cells and B-cells compartment accept a allogenic bone marrow graft

A

true

22
Q

natural antibodies have the following characteristics

A

all of the above

low affinity, low specificity, harmless, have some rule for clearing infection

23
Q

in natural tolerance 95% of apoptisis (PCD) of T cells found in

A

thymus

24
Q

central tolerance is within _____

A

thymus

25
Q

Post streptococal (glomerulonephritis)

A

immune complex disease

26
Q

arthus reaction

A

Type III hypersensitivity (local)

27
Q

serum sickness

A

type III hypersensitive (systemic)

28
Q

contact hypersensit-IV-ity

A

type IV

29
Q

T suppressor cells prevent ____ to make antibodies, and also prevent ______ from maturing into T-cytotoxic cells

A

B-cells, T cells

30
Q

T/F prexisting infections can have positive or negative effects on immune response

A

true

31
Q

this is an induced tolerance in which an animal will fail to respond to non-self antigens (all exogenous antigens) from outside the body that would normally be immunologic

A

acquired tolerance

32
Q

which of the following factors are involved in autoimmune disease

A

All of the above

infection, hormonal, genetic

33
Q

these monkey antigens (Rh factor) are presenting in __ of humans and absent in the other ___

A

85%, 15%

34
Q

transfusion reaction may cause

A

all of the above

Immunology (3 decks)

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