Final Flashcards

1
Q

Between asthma and COPD, which causes irreversible airflow limitation?

A

COPD

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2
Q

Which is more responsive to steroids, COPD or asthma?

A

Asthma

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3
Q

What spirometry is required for the diagnosis of COPD?

A

FEV1/FVC ratio of < 0.70

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4
Q

What is FEV1?

A

Forced expiratory volume in 1 second

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5
Q

What is FVC?

A

Forced vital capacity

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6
Q

What is LAMA?

A

Long acting muscarinic agonist

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7
Q

Which SABA theoretically causes less tachycardia?

A

Levalbuterol

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8
Q

LABA monotherapy does not increase risk of death in COPD or asthma?

A

COPD

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9
Q

Can LABA be used as monotherapy in asthma?

A

No

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10
Q

Which has fewer side effects, LABA or LAMA?

A

LAMA

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11
Q

Is monotherapy with inhaled steroids approved for use in asthma or COPD?

A

Asthma

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12
Q

When should ICS be added for COPD?

A

When the pt has exacerbations despite being on LABA/LAMA

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13
Q

When to add a PDE-4 inhibitor to COPD therapy?

A

In severe COPD

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14
Q

Should SABA ever be used alone in asthma?

A

No, should be used with ICS

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15
Q

Does all opioid physical dependence lead to addiction?

A

No

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16
Q

Can schedule II medications be refilled?

A

No

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17
Q

Is informed consent required for pain management?

A

Yes

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18
Q

What percent of caucasians are poor metabolizers of codeine?

A

About 10%

19
Q

Can an opioid naive pt tolerate Fentanyl?

A

Usually not

20
Q

Which opioid prolongs QT?

A

Methadone

21
Q

What is affinity?

A

The strength with which a drug binds to a receptor

22
Q

What is receptor dissociation?

A

The speed with which a drug disengages from a receptor

23
Q

Why is naloxone added to buprenorphine?

A

To decrease abuse potential

24
Q

Is opioid tolerance reversible?

A

Yes

25
Q

What is the max dose of Tylenol for chronic use?

A

2-3 grams per day

26
Q

What is the benefit of salsalate?

A

Lower risk of gastric side effects as compared to other NSAIDs

27
Q

What effect can ibuprofen have on a pt who takes ASA?

A

Can reduce cardiovascular benefits of ASA

28
Q

Which two NSAIDs do not interfere with platelet aggregation?

A

Cox-2 inhibitors and salsalate

29
Q

What should you monitor when first starting SNRI?

A

Blood pressure

30
Q

8% capsaicin must be applied by who?

A

A healthcare provider

31
Q

Gemfibrozil with a statin increases risk of what?

A

Myopathy/ rhabdo

32
Q

Can you give gemfibrozil with a statin?

A

No

33
Q

Can a fenofibrate be given with a statin?

A

Yes

34
Q

Which raises LDL, EPA or DHA?

A

DHA

35
Q

Canaglifozin raises risk of what?

A

Foot and leg amputations

36
Q

Can sulfonylureas be given to someone with a sulfa allergy?

A

No

37
Q

DDP4 inhibitors increase risk of what?

A

Heart failure

38
Q

Insulin can lower levels of which electrolyte?

A

Potassium

39
Q

What is the preferred first line agent in gestational diabetes?

A

Insulin

40
Q

What is the blood pressure goal for diabetics?

A

Less than 130/80

41
Q

Afreeza is contraindicated in diabetic pts with which comorbidities?

A

COPD/ asthma

42
Q

Which statin has the least drug-drug interactions?

A

Pravastatin

43
Q

When should ACE/ARB not be given to a diabetic pt?

A

If they have normal BP and normal urine creatinine