Final Flashcards
Between asthma and COPD, which causes irreversible airflow limitation?
COPD
Which is more responsive to steroids, COPD or asthma?
Asthma
What spirometry is required for the diagnosis of COPD?
FEV1/FVC ratio of < 0.70
What is FEV1?
Forced expiratory volume in 1 second
What is FVC?
Forced vital capacity
What is LAMA?
Long acting muscarinic agonist
Which SABA theoretically causes less tachycardia?
Levalbuterol
LABA monotherapy does not increase risk of death in COPD or asthma?
COPD
Can LABA be used as monotherapy in asthma?
No
Which has fewer side effects, LABA or LAMA?
LAMA
Is monotherapy with inhaled steroids approved for use in asthma or COPD?
Asthma
When should ICS be added for COPD?
When the pt has exacerbations despite being on LABA/LAMA
When to add a PDE-4 inhibitor to COPD therapy?
In severe COPD
Should SABA ever be used alone in asthma?
No, should be used with ICS
Does all opioid physical dependence lead to addiction?
No
Can schedule II medications be refilled?
No
Is informed consent required for pain management?
Yes
What percent of caucasians are poor metabolizers of codeine?
About 10%
Can an opioid naive pt tolerate Fentanyl?
Usually not
Which opioid prolongs QT?
Methadone
What is affinity?
The strength with which a drug binds to a receptor
What is receptor dissociation?
The speed with which a drug disengages from a receptor
Why is naloxone added to buprenorphine?
To decrease abuse potential
Is opioid tolerance reversible?
Yes
What is the max dose of Tylenol for chronic use?
2-3 grams per day
What is the benefit of salsalate?
Lower risk of gastric side effects as compared to other NSAIDs
What effect can ibuprofen have on a pt who takes ASA?
Can reduce cardiovascular benefits of ASA
Which two NSAIDs do not interfere with platelet aggregation?
Cox-2 inhibitors and salsalate
What should you monitor when first starting SNRI?
Blood pressure
8% capsaicin must be applied by who?
A healthcare provider
Gemfibrozil with a statin increases risk of what?
Myopathy/ rhabdo
Can you give gemfibrozil with a statin?
No
Can a fenofibrate be given with a statin?
Yes
Which raises LDL, EPA or DHA?
DHA
Canaglifozin raises risk of what?
Foot and leg amputations
Can sulfonylureas be given to someone with a sulfa allergy?
No
DDP4 inhibitors increase risk of what?
Heart failure
Insulin can lower levels of which electrolyte?
Potassium
What is the preferred first line agent in gestational diabetes?
Insulin
What is the blood pressure goal for diabetics?
Less than 130/80
Afreeza is contraindicated in diabetic pts with which comorbidities?
COPD/ asthma
Which statin has the least drug-drug interactions?
Pravastatin
When should ACE/ARB not be given to a diabetic pt?
If they have normal BP and normal urine creatinine