Final Flashcards

1
Q

Between asthma and COPD, which causes irreversible airflow limitation?

A

COPD

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2
Q

Which is more responsive to steroids, COPD or asthma?

A

Asthma

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3
Q

What spirometry is required for the diagnosis of COPD?

A

FEV1/FVC ratio of < 0.70

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4
Q

What is FEV1?

A

Forced expiratory volume in 1 second

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5
Q

What is FVC?

A

Forced vital capacity

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6
Q

What is LAMA?

A

Long acting muscarinic agonist

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7
Q

Which SABA theoretically causes less tachycardia?

A

Levalbuterol

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8
Q

LABA monotherapy does not increase risk of death in COPD or asthma?

A

COPD

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9
Q

Can LABA be used as monotherapy in asthma?

A

No

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10
Q

Which has fewer side effects, LABA or LAMA?

A

LAMA

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11
Q

Is monotherapy with inhaled steroids approved for use in asthma or COPD?

A

Asthma

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12
Q

When should ICS be added for COPD?

A

When the pt has exacerbations despite being on LABA/LAMA

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13
Q

When to add a PDE-4 inhibitor to COPD therapy?

A

In severe COPD

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14
Q

Should SABA ever be used alone in asthma?

A

No, should be used with ICS

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15
Q

Does all opioid physical dependence lead to addiction?

A

No

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16
Q

Can schedule II medications be refilled?

A

No

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17
Q

Is informed consent required for pain management?

A

Yes

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18
Q

What percent of caucasians are poor metabolizers of codeine?

19
Q

Can an opioid naive pt tolerate Fentanyl?

A

Usually not

20
Q

Which opioid prolongs QT?

21
Q

What is affinity?

A

The strength with which a drug binds to a receptor

22
Q

What is receptor dissociation?

A

The speed with which a drug disengages from a receptor

23
Q

Why is naloxone added to buprenorphine?

A

To decrease abuse potential

24
Q

Is opioid tolerance reversible?

25
What is the max dose of Tylenol for chronic use?
2-3 grams per day
26
What is the benefit of salsalate?
Lower risk of gastric side effects as compared to other NSAIDs
27
What effect can ibuprofen have on a pt who takes ASA?
Can reduce cardiovascular benefits of ASA
28
Which two NSAIDs do not interfere with platelet aggregation?
Cox-2 inhibitors and salsalate
29
What should you monitor when first starting SNRI?
Blood pressure
30
8% capsaicin must be applied by who?
A healthcare provider
31
Gemfibrozil with a statin increases risk of what?
Myopathy/ rhabdo
32
Can you give gemfibrozil with a statin?
No
33
Can a fenofibrate be given with a statin?
Yes
34
Which raises LDL, EPA or DHA?
DHA
35
Canaglifozin raises risk of what?
Foot and leg amputations
36
Can sulfonylureas be given to someone with a sulfa allergy?
No
37
DDP4 inhibitors increase risk of what?
Heart failure
38
Insulin can lower levels of which electrolyte?
Potassium
39
What is the preferred first line agent in gestational diabetes?
Insulin
40
What is the blood pressure goal for diabetics?
Less than 130/80
41
Afreeza is contraindicated in diabetic pts with which comorbidities?
COPD/ asthma
42
Which statin has the least drug-drug interactions?
Pravastatin
43
When should ACE/ARB not be given to a diabetic pt?
If they have normal BP and normal urine creatinine