final

Question 1

hexokinase negative regulated by

Answer 1

G6P
turns g6p to f6p

Question 2

pyruvate kinase positively regulated by

Answer 2

F6BP

Question 3

GLUT1

Answer 3

passive uptake of glucose

Question 4

GLUT2

Answer 4

B-cell in pancreas

Question 5

GLUT3

Answer 5

non-insulin mediated uptake in CNS + neurons

Question 6

GLUT4

Answer 6

insulin stimulated glucose uptake in muscle + adipose

Question 7

PFK1 regulation

Answer 7

positively regulated by AMP + fructose
negatively regulated by ATP + Citrate + H

Question 8

rate limiting step of gluconeogenesis

Answer 8

PEP carboxylate that turns

Question 9

G6Pase

Answer 9

reverses hexokinase
liver only organ in body to produce G6Pase

Question 10

Frutose bisphosphate phosphatase

Answer 10

reverses PFK1

Question 11

pyruvate dehydrogenase

Answer 11

pyruvate + coa + nad+ –> acetyl-coa + co2 + nadh

Question 12

ketone bodies

Answer 12

used in brain + skeletal muscles as fuel when glucose is low
ketone body converted to acetyl-coa then produces atp

Question 13

TCA cycle

Answer 13

Acetyl-coa –> 2co2 + 3NADH + 1FADH + 1GTP(ATP)

Question 14

pyruvate carboxylase

Answer 14

first enzyme in gluconeogenesis
converts pyruvate to oxaloacetate

Question 15

oxidative respiration

Answer 15

carbon fuels + O2 –> CO2 + h2o + ATP

Question 16

FA synthesis

Answer 16

occurs in cytosol
acetyl group not water soluble so transferred onto oxaloacetate to create citrate
commitment step: conversion of acetyl-Coa to malonyl coa
uses NADH
8 acetyl-coa + 7 ATP + 14 NADPH —> palmitate + 7 ADP + 14 NADP

Question 17

FA oxidation

Answer 17

occurs in mitochondria
palmitate + ATP 7 FAD + 7NAD+ –> 8 acetyl-coa + 7FADH + 7 NADH + AMP

Question 18

HMG-CoA reductase

Answer 18

converts HMG coa to mevalonate in cytosol

Question 19

3 irreversible steps for gluconeogenesis

Answer 19

carboxykinase
f16BPase
G6Pase