Final Flashcards
hypothalamus: location, hormone type/produced, function
base of the brain, hormones that stimulate or suppress the release of hormones in the pituitary gland, controls water balance, sleep, temperature, appetite, and blood pressure
pineal gland: location, hormone type/produced, function
middle of the brain, melatonin, regulate circadian clock
pituitary gland: location, hormone type/produced, function
below the brain, controls many functions of other endocrine glands
thyroid: location, hormone type/produced, function
front of the neck, metabolism
adrenal glands: location, hormone type/produced, function
on top of the kidneys, corticosteroid hormones and epinephrine, maintaining blood pressure and regulating
metabolism
gut: location, hormone type/produced, function
stomach, small & large intestine, regulates digestion and hunger
adipose tissue: location, hormone type/produced, function
all over body, leptin, regulation of hunger and fat storage
pancreas: location, hormone type/produced, function
behind the stomach, insulin and glucagon, regulate blood sugar and digestion
ovaries: location, hormone type/produced, function
either side of uterus, estrogen and progesterone, contain eggs and release sex hormones
testis: location, hormone type/produced, function
outside body, testosterone, contain sperm and release sex hormone
placenta: location, hormone type/produced, function
inside uterus, human chorionic gonadotropin (hcg), estrogen + progesterone, stimulates corpus luteum to release progesterone
hypothalamus: thyrotropin releasing hormone
targets anterior pituitary to stimulate release of TSH
hypothalamus: corticotropin releasing hormone
promotes production of adrenocorticotropin hormone (ACTH)
hypothalamus: gonadotropin releasing hormone
promotes production of FSH and LH in anterior pituitary
hypothalamus: growth hormone releasing hormone (GHRH)
promotes production of growth hormone
hypothalamus: oxytocin
stimulates production of oxytocin in pituitary
hypothalamus: antidiuretic hormone (ADH)
stimulates production of ADH in pituitary
posterior pituitary: oxytocin
targets uterus and mammary glands, stimulates uterine contractions during labor, release of milk by mammary glands
posterior pituitary: antidiuretic hormone (vasopressin)
stimulates reabsorption of water by the kidneys
anterior pituitary: FSH
targets gonads, egg development, sperm production and maturation, promote sex hormone production which feedback to inhibit FSH and LH production
anterior pituitary: LH
targets gonads, ovulation (egg release), promote sex hormone production which feedback to inhibit FSH and LH production
anterior pituitary: prolactin
breast growth/milk release after birth
anterior pituitary: growth hormone
targets soft tissue and bones to promote cell division, protein synthesis and bone growth
anterior pituitary: thyroid stimulating hormone (TSH)
stimulates release of thyroid hormones
anterior pituitary: adrenocorticotropin hormone
targets adrenal glands to produce cortisol
pineal: melatonin
targets brain to control circadian and seasonal rhythms
thyroid: thyroid hormone
targets all tissues and increases metabolic rate, regulating growth and development
adrenal cortex: cortisol
targets all tissues, regulates blood pressure, long term stress response, day/night cycle, inflammation
adrenal cortex: aldosterone
targets kidneys to regulate sodium and potassium levels, fluid levels and blood pressure
adrenal medulla (under neural control): adrenaline/noradrenaline (a.k.a epinephrine/norepinephrine)
targets cardiac/other muscles, released in emergency situations and raises blood glucose levels (fight or flight response)
stomach: gastrin
stimulates gastric juice production
stomach: ghrelin
targets hypothalamus and the amygdala (reward center in brain) to regulate hunger (increases appetite)
stomach: somatostatin
targets pituitary and gut to inhibit synthesis of ghrelin and gastrin
intenstines: secretin
helps pancreas to neutralize acid, inhibits secretion of gastric acid in stomach
intestines: cholecystokinin (CCK)
stimulates gallbladder to contract
and release bile into intestine and stimulates release of digestive
enzymes from the pancreas
intestines: somatostatin
inhibits synthesis of CCK
adipose tissue: leptin
regulates hunger (decreases appetite)
pancreas: insulin
lowers blood glucose
pancreas: glucagon
raises blood glucose
pancreas: somatostatin
inhibits release of glucagon and insulin
testes: androgens (testosterone)
targets gonads to promote male sex characteristics, inhibits FSH and LH
ovaries: estrogen and progesterone
targets gonads to promote female sex characteristics, inhibits FSH and LH
placenta: hCG (human chorionic gonadotropin), estrogen, progesterone
targets corpus luteum, placenta, and fetus to develop fetus and maintain pregnancy
What is the Hypothalamic-Pituitary-Gonadal Axis? Describe
Hypothalamic-Pituitary-Gonadal Axis; negative feedback loop
- Hyp produces GnRH (Gonadotropin Releasing Hormone)
- Anterior pituitary releases FSH and LH after stimulation by GnRH
- FSH and LH promote production of testosterone, estrogen, and progesterone depending on sex, these hormones feedback to the hyp to shut down the process
What hormone predicts ovulation?
LH, large spike before ovulation
What hormone is only produced when pregnant and thus is used to detect pregnancy?
hcG; human chorionic gonadotropin; produced only when pregnant (by placenta)
First fourteen days of menstrual cycle?
Follicular phase; follicular growth and egg maturation
XY sex determination pathway
Y chromosome has srYgene → srYgene produces TDF hormone (testis determining factor) → acts on primitive gonads to produce MIS (Mullerian Inhibiting Substance) to prevent female structures // produces testosterone to create Wolffian ducts and thus male structures
XX sex determination pathway
No testosterone → no development of Wolffian duct // no MIS → development of Mullerian ducts and thus female structures
What is the one relevant example of a positive feedback loop?
Oxytocin release during labor; Stretching of cervix = release of oxytocin = stretching of the cervix, cyclic
How long is a trimester?
13 weeks
How long is pregnancy?
~270 days
what inhibits melatonin production?
light received through the eyes
what fat is under the skin?
subcutaneous
what fat surrounds organs?
visceral
who has more visceral vs more subcutaneous gender wise?
men have more visceral, women have more subcutaneous
what makes up the pancreas?
islets of langerhans
type one diabetes
body does not produce insulin
type two diabetes
body’s cells become resistant to insulin