fibrotic lung disease

Question 1

a low FVC reflects which type of lung disease?

Answer 1

restrictive
(asthma / p.fibrosis / sarcoid)

Question 2

a low FEV1 reflects which type of lung disease

Answer 2

obstructive
(COPD / EMPSYEMA)

Question 3

what is tlco?

Answer 3

transfer factor of carbon monoxide
indication for total absorptive capacity

Normal = >75%

Question 4

low FEV1 / FVC ratio indicates which lung defect?

Answer 4

Obstructive

Question 5

high TLCO / high KCO ratios are seen in which 4 conditions?

Answer 5

polycythemia
high cardiac output
pulm. haemorrhage
early asthma

Question 6

low TLCO / KCO ratios are seen in which condtions?
(what is the ‘rule’)

Answer 6

conditions ‘stopping transfer’

PE
Anaemia
ILD
Pulm odema
pneumonia

Question 7

which 3 conditions show a TLCO low but KCO high?

Answer 7

pneumonectomy
chest wall restriction
neuromuscular

Question 8

does EAA cause an upper or lower lobe fibrosis?

Answer 8

upper

Question 9

does CFA cause an upper or lower lobe fibrosis?

Answer 9

lower

Question 10

does ank spond cause an upper or lower lobe fibrosis?

Answer 10

upper

Question 11

does RA cause an upper or lower lobe fibrosis?

Answer 11

lower

Question 12

which 4 conditions cause a lower lobe fibrosis?

Answer 12

RA
CFA
Asbestosis
SLE

Question 13

which 4 conditions cause an upper lobe fibrosis?

Answer 13

EAA
Ank Spond
Silicosis
TB

Question 14

which drug use for treating UTI causes fibrosis?

Answer 14

nitro

Question 15

which drug use for treating AF causes fibrosis?

Answer 15

amiodarone

Question 16

which drugs use for treating RA cause fibrosis?

Answer 16

Methotrexate
Sulphasalazine

Question 17

which drugs use for treating cancer cause fibrosis?

Answer 17

bleomycin
cyclophosphomide

Question 18

what is the normal PCWP?

Answer 18

<18mmHg

Question 19

in ARDS what is the PCWP?

Answer 19

‘normal’
<18mmHg