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Oral Pathology and Medicine > Fibroosseous Lesions Of Jaws > Flashcards

Fibroosseous Lesions Of Jaws Flashcards

1
Q

Gene undergoing mutation for FIBROUS
DYSPLASIA

A

GNAS 1

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2
Q

McCune Albright Syndrome consists of

A

(a) Cafe au Lait spots (Melanocytes)
(b) Fibrous dysplasia (monostotic or polystotic) (osteoclasts)
(c) Precocious puberty (Endocrine cells)

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3
Q

Jaffe’s Syndrome consists of

A

Cafe au Lait spots (Melanocytes)

Fibrous dysplasia (polystotic) (osteoclasts)

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4
Q

most common bone affected because of monostotic
fibrous dysplasia

A
  1. Ribs
  2. Jaw bone
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5
Q

Radiographic appearance for fibrous dysplasia:

A

• Ground glass appearance
• orange peel / peau d orange
• frosted glass appearance

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6
Q

ground glass
appearance is a characteristic feature for

A

Hyperparathyroidism

< fibrous dysplasia

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7
Q

IOPA of fibrous Dysplasia shows

A

Finger print appearance

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8
Q

Finger print appearance is seen in

A

IOPA of fibrous Dysplasia

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9
Q

Histopathology of fibrous dysplasia shows

A

→ Woven - immature bone seen here
→ cuneiform /chinese letter pattern
→ Alphabet soup pattern

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10
Q

Woven - immature bone seen in

A

Histopathology of fibrous dysplasia shows

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11
Q

cuneiform /chinese letter pattern

A

Histopathology of fibrous dysplasia shows

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12
Q

Alphabet soup pattern seen in

A

-Histopathology of fibrous dysplasia shows

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13
Q

What is contraindicated in fibrous dysplasia and why

A

Radiotherapy is contraindicated as osteosarcoma can develop

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14
Q

Mazabraud’s Syndrome

A

fibrous Dysplasia with intramuscular myxomas

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15
Q

fibrous Dysplasia with intramuscular myxomas seen with

A

Mazabraud’s Syndrome

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16
Q

Most serious complication of polystotic fibrous dysplasia is
.

A

Osteosarcoma.

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17
Q

Gene mutation in Cherubism

A

SH3 BP2 gene

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18
Q

SH3 BP2 gene mutation seen in

A

Cherubism

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19
Q

Eye to Heaven appearance seen with

A

Cherubism

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20
Q

Radiographic appearance of
Cherobism.

A

floating tooth apperance

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21
Q

floating tooth apperance

A

-Radiographic appearance of
Cherobism

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22
Q

Which is the Radiographic grading of
Cherubim.

A

Arnott Radiographic grading of
Cherubim.

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23
Q

→ Syndromes associated with
Cherubism

A

• Ramon Syndrome
• Rutherford Syndrome
• Noonan syndrome

24
Q

The following syndromes are associated with?
• Ramon Syndrome
• Rutherford Syndrome
• Noonan syndrome associated with

A

Cherubism

25
Q

Histopathology of cherubism shows

A

→ Giant cells which are TRAP positive (Tastarate resistant acid phosphatase)
→ Perivascular eosinophilic cutting

26
Q

→ Giant cells which are TRAP positive (Tastarate resistant acid phosphatase)
→ Perivascular eosinophilic cutting
Seen with

A

Histopathology of cherubism

27
Q

Focal Cemento osseous dysplasia site :

A

Periapical mandibular molar

28
Q

Periapical cemento osseous dysplasia site :

A

Mandibular anterior region

29
Q

Florid Cemento osseous dysplasia site :

A

Multi quadrant varient of cemento osseous dysplasia

30
Q

Grenz zone seen in

A

Ossifying Fibroma
The pathology is separated from surrounding healthy bone by this zone of connective tissue.

31
Q

What connective tissue zone is present in Ossifying Fibroma

A

Grenz zone

32
Q

Types of Juvenile Ossifying Fibroma

A
  1. Trabecular type
  2. Psammamatoid type
33
Q

Parry Romberg syndrome aka

A

progressive hemifacial atrophy

34
Q

progressive hemifacial atrophy aka

A

Parry Romberg syndrome

35
Q

Crouzon Syndrome aka

A

Craniofacial dysostosis Craniosynostosis

36
Q

Gene responsible for Crouzon Syndrome

A

Gene: FGFR 2
FGFR 3

37
Q

frog faces seen in

A

Crouzon Syndrome

38
Q

Radiographic feature f
Crouson Syndrome

A

• Beaten metal appesance
• Copper beaten appesance

39
Q

• Beaten metal appesance
• Copper beaten appesance seen in

A

Radiographic feature of
Crouson Syndrome

40
Q

Tower skull seen in

A

Apert Syndrome

41
Q

Mitten hand and sock feet appearance seen in

A

Apert Syndrome

42
Q

Treacher Collins
Syndrome aka

A

Mandibulofacial dysostosis
And
First arch syndrome

43
Q

Treacher Collins
Syndrome gene

A

gene: Treachilin a TCOF

44
Q

Coloboma with normal vision seen in

A

Treacher Collins
Syndrome

45
Q

Fish face apperance seen in

A

Treacher Collins
Syndrome

46
Q

Triad of Pierre Robin Syndrome

A

Mandibular micrognathia
• Glossoptosis (OSA) (obstructive sleep apnea)
• Cleft palate

47
Q

Mandibular micrognathia
• Glossoptosis (OSA) (obstructive sleep apnea)
• Cleft palate
Seen in

A

Triad of Pierre Robin Syndrome

48
Q

Brush field spot seen in Iris in

A

Down Syndrome

49
Q

Tongue features of

Down Syndrome

A

• fissured tongue
• Macroglossia.

50
Q

Paget Disease aka

A

Osteitis Deformans

51
Q

Osteitis Deformans aka

A

Paget Disease

52
Q

Paget Disease gene

A

gene: sequestosome I
gene. SQS TMI as
p 62

53
Q

gene: sequestosome I
gene. SQS TMI as
p 62

Seen in

A

Paget Disease
Or
Osteitis Deformans

54
Q

Lion like face known as Leontasis Ossea seen in

A

Paget Disease
Or
Osteitis Deformans

55
Q

Cotton wool upperance is radiographic feature of

A

Paget Disease
Or
Osteitis Deformans

56
Q

Gorham’s
Disease aka

A

Phantom bone Syndrome aka Massive Osteolysis

57
Q

Phantom bone Syndrome aka Massive Osteolysis aka

A

Gorham’s
Disease

Oral Pathology and Medicine (4 decks)

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