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Oral Pathology and Medicine > Diseases Of Skin > Flashcards

Diseases Of Skin Flashcards

1
Q

What is Christ - Siemen’s Tourian Syndrome?

A

Type I : Hyponidrotic form of
Ectodermal Dysplasia.

3 H seen here
• Hypohydrosis
• Hypotrichasis
• Hypodontia

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2
Q

Genetic nature of Christ - Siemens Tourian
Syndrome

A

X- linked recessive disorder.

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3
Q

Only condition where Anodontia is seen is

A

Ectodermal Dysplasia (although very rarely)

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4
Q

What is Lyon’s hypothesis /
Lyonization

A

It is a hypothesis for any
✗ -linked recessive
disorder

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5
Q

Genetic nature of Psoriasis

A

Auto immune skin
disease

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6
Q

What is Koebner’s phenomenon

A

Aka Isomorphic effect

→ trauma induced lesion
formation

(also seen in lichen Planus but is characteristic of
Psoriasis)

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7
Q

What is AUSPITZ’s Sign

A

Seen with psoriasis

pinpoint bleeding spots
when silvery white scale is removed.

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8
Q

Which is the sign that shows

pinpoint bleeding spots
when silvery white scale is removed..

And is seen with which condition.

A

AUSPITZ’s Sign seen in psoriasis

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9
Q

Histopathology of psoriasis shows

A

test tube shaped rete ridges

Is also seen with:
Gingival fibromatosis and
Drug induced gingival enlargement

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10
Q

-Test tube shape Rete Ridges
Shape seen with

A

• Psoriasis
• Gingival fibromatosis
• Drug induced gingival
enlargement

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11
Q

What are Munro’s micro abscess

A

Intra epithelial micro abscess
Seen in psoriasis

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12
Q

What is Psoriasiform lesion

A

Geographic tonge
• Not related to Psoriasis.

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13
Q

LICHEN PLANUS
• first described by

A

Erasmus Wilson

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14
Q

Genetic nature of

LICHEN PLANUS

A

Auto immune
(T- lymphocyte mediated)

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15
Q

What is Grinspan Syndrome

A

lichen Planers + Diabetes Mellitus + Hypertension

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16
Q

What is Greenspan lesion

A

Is another name for Oral Hairy leukoplakia.

Not related to lichen Planus

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17
Q

Whicham’s striae /
honitons lace

A

.. seen ONLY in lichen
Planus.

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18
Q

Whicham’s striae baker.

A

honitons lace
seen ONLY in lichen
Planus.

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19
Q

honitons lace
Aka

A

Whicham’s striae

seen ONLY in lichen
Planus.

20
Q

Which is the most common clinical type of lichen plants

A

Reticular lichen planus

21
Q

What is the confirmatory diagnosis of lichen Planus.

A

DIF
Direct immuno flourescence

(DIF can be done for an
autoimmune disease)

22
Q

Saw tooth Rete pegs seen in

A

Hypertrophic lichen Planus

23
Q

Max-Jacob /Max-Joseph
space seen in

A

Hypertrophic lichen Planus

between the epithelium and connective tissue

24
Q

Which type of lichen Planus is a premalignant condition

A

Erosive lichen planus

(here squamous cell carcinoma eventually develops)

25
Q

Genetic nature of PEMPHIGUS

A

’

Autoimmune

26
Q

cerebriform tongue seen with

A

Pemphigus vegetans

27
Q

Histopathology of Pemphigus shows:

A

Tzank cells

28
Q

Tzank test is done for diagnosis o

A

① Pemphigus
② Herpes simplex

29
Q

DIF (direct immunofluorescence) of Pemphigus shows

A

IgG in the Intercellular area with Chicken wire pattern or fish net pattern.

30
Q

Chicken wire pattern or fish net pattern seen in the histopathology of

A

DIF
(direct immunofluorescence) of Pemphigus

31
Q

Treatment of Pemphigus

A

Pulse Therapy
→ DCP pulse therapy
(Dexamethasone cyclophosphamide)
[DCP can cause testicular diseases in males and hence Azathioprine is used instead]

32
Q

Nikolsky’s sign seen in

A

Pemphigus

33
Q

Asboe Hansen sign
Aka and seen in

A

Nikolsky’s sign seen in Pemphigus

34
Q

Pemphigus foliaceus
aka brazilian wildfire

A

brazilian wildfire

35
Q

brazilian wildfire aka

A

Pemphigus foliaceus

36
Q

pemphigus erythematosus
aka

A

Senear- usher - syndrome

37
Q

Senear- usher - syndrome aka

A

pemphigus erythematosus

38
Q

Hailey Hailey disease aka

A

familial benign Pemphigus

39
Q

familial benign Pemphigus aka

A

Hailey Hailey disease

40
Q

Genetic nature of PEMPHIGOID

A

Autoimmune

(Ig G4)

41
Q

DIF in PEMPHIGOID shows

A

deposition of IG g and C 3 in the basement membrane zone in Linear pattern.

42
Q

Stevens Johnson syndrome aka

A

Erythema Multiforme major

43
Q

Erythema Multiforme major aka

A

Stevens Johnson syndrome

44
Q

Lyell’s disease aka

A

TENS (toxic epidermal necrolysis)

45
Q

Target-like/Iris/ bulls eye lesions seen in

A

Erythema Multiforme

46
Q

BLOODY ENCRUSTATIONS seen on lips in

A

Erythema Multiforme

Oral Pathology and Medicine (4 decks)

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