Fibromyalgia Flashcards

1
Q

FM is a syndrome of:

A

Persistent, widespread pain, stiffness, fatigue, disrupted and unrefreshing sleep, cognitive difficulties, anxiety and depression

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2
Q

FM typically presents in

A

young or middle aged women

MC in AA women in US, adolescence

peak prevalence is 60-70

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3
Q

FM patho

A

disorder of central pain processing or a syndrome of central sensitivity

altered functional connectivity and chemistry in pain processing system of the brain

therefore they experience increased sensation

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4
Q

pain response in fibromyalgia

A

while usually pain is adaptive – in fibromyalgia the pain response is maladaptive

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5
Q

fibromyalgia etiologies (list)

A
  1. genetics
  2. female sex hormones
  3. sleep
  4. physical deconditioning
  5. stress dysregulation
  6. psychologic factors
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6
Q

genetics in FM

A

altered serotonin metabolism

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7
Q

sleep/deconditioning in FM

A

sleep poorly + more painful days

sedentary persons experience sleep disruption

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8
Q

FM symptoms

A
  1. widespread MSK pain
  2. fatigue
  3. anxiety and depression
  4. headache
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9
Q

MSK pain in FM

A

hurts all over

pain is localized to muscle + joints

100% of patients

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10
Q

fatigue in FM

A

unrefreshed from sleep

frequently awaken early in AM and difficulty getting back to sleep

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11
Q

original diagnostic evaluation of FM

A

widespread pain and tenderness at least 3 months both above and below waist bilaterally

mush have 11/18 points to be tender on FM

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12
Q

WPI

A

ask patient about 19 areas of pain in last week

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13
Q

SS score

A

fatigue, waking unrested, cognitive symptoms and clinician assigns severity score

low, mod, high to history max 12

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14
Q

diagnostic criteria for FM

A
  1. WPI > 7 + SS >5 or WPI 3-6 and SS > 9
  2. symptoms present for at least 3 months
  3. not a better disorder
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15
Q

FM tx goals

A

reducing major symptoms of d/o

chronic widespread pain, fatigue, insomnia, and cognitive dysfunction

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16
Q

non RX tx of FM

A

emphasis of sleep and sleep hygiene

tx underlying psych disorder

exercise and referral `

17
Q

FM medications

A
  1. TCAs (amytriptilline) low dose at night
  2. Pregabalin
  3. duloxetine
18
Q

lyrica and cymbalta

A

Cymbalta AM is better for depression

lyrica preferred for patients who have more issues with sleep

19
Q

management of pts unresponsive to mono therapy

A
  1. combining medications
  2. specialist referral
  3. CAM (tia chi, yoga)
20
Q

fibromyalgia prognosis

A

mortality not increased, but suicide present

incomplete symptom relief common and likely disabled

21
Q

what is associated with poor outcomes in FM

A

unemployment
obesity
Low SES
female sex