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Hematology 2 > Fibrinolysis > Flashcards

Fibrinolysis Flashcards

1
Q

Process wherein the temporary fibrin clot is systematically and gradually dissolved in order to restore normal blood flow

A

Fibrinolysis

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2
Q

Major inhibitor of plasmin

A

Alpha2-antiplasmin

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3
Q

Plasminogen activators

A

FXIIa, Kallekrin, HMWK

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4
Q

Plasmin

A

Fibrinolysin (lyses that fibrin clot)

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5
Q

Inhibitors of Fibrinolysis

A
  1. Alpha2-antiplasmin
  2. Alpha1-antitrypsin
  3. Apha2-macroglobulin
  4. Thrombospondin
  5. Plasminogen activator-inhibitor 1 & 2
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6
Q

Uncontrolled, inappropriate formation of fibrin within the blood vessels

A

Disseminated Intravascular coagulation

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7
Q

Screening procedure for the measurement of fibrinolytic activity

A

Euglobulin clot lysis time

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8
Q

Administration of Heparin

A

IV

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9
Q

First agent administered as an anticoagulant to patients with DIC

A

Heparin

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10
Q

Heparin is reversed by

A

Protamine sulfate

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11
Q

Oral anticoagulants

A

Warfarin, coumadin, coumarin (all are Vit. K Antagonists)

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Hematology 2 (3 decks)

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