fibre types & athletic performances Flashcards
contraction speed: what does the unloaded
shortening velocity experiment demonstrate
demonstrate differences
in contractile speed between muscle fibre
types
Contraction speed: describe the different speeds of type I, IIA and IIX
Type I fibres are ≈3 times
slower than IIA and ≈10*
times than IIX
limitation to the Unloaded shortening velocity experiment
dramatically different temperatures from our body temp to what the experiment is done at
solution to temperature problem in Unloaded shortening velocity experiment
In vitro motility (IVM) assay:
myosin function at molecular level
are male fibres stronger than female fibres and why
Male fibres are stronger, more force is generated because their Cross-sectional area are larger
describe the specific tensions between male and females
When corrected for the size difference, female fibres develop the same specific tension (amount of force per unit of cross sectional area) as male fibres
describe the specific tensions between the different fibres
Type IIX fibres generate greater specific tension compared to type I and
IIA fibres
do fibre NUMBER differ between sexes
Studies in the species where all fibres can be counted and compared between homologous muscles (e.g.
mice) indicated that there is no significant difference between male and females
can fibres co- express more than one MyHC (Myosin heavy chains)
yes as Slower isoform of myosin heavy chains (MyHC) determines the contraction speed of a fibre unless faster isoform is appreciably abundant (>50%)
Does variation in the fibre types have functional consequences?
force generated at high
(but not low) velocity and maximal speed of contraction positively correlate with proportion
of FT fibres.
how to Estimate muscle fibres in biceps
Cross-sectional area of the muscle (left)
* Mean fibre cross-sectional area from the biopsy (right)
what is the Number of fibres in b. brachii
Number of fibres in b. brachii between 172,085 and 418,884 (>2-fold difference)
what does the hypertrophy of the fibres in body builders do
contribute to a larger cross-sectional area (CSA) of the muscle (average CSA in body builders nearly 2- fold larger than in untrained subjects)
what does the proportion of fast fibres in the muscle corelate with
the ability to develop dynamic force and power
which muscle fibre contract slower
Type 1 fibres contract slower than type 2A or 2X fibres