FEVER ( PYREXIA ) Flashcards
A classical sign of infection
Fever
The immune response releases chemical called ______ which stimulate the “hypothalamus” leading elevation of the body thermostat.
CYTOKINE
Causes of Fever:
1.infection
2. Cell injury
3.neoplastic diseases or cancer
Alterations in the body temperature
- HYPERpyrexia
- NORMAL
- HYPOTHERMIA
Hyperpyrexia & Pyrexia =
FEBrile
Normal =
AFEbrile
Types of Fever
1.INtermittent
2.RElapsinh
Fever withIN hours
INtermittent
Fever : Duration DAYs
Relapsing
“Wide” range of temperature: more than 2° C
REMIttent
MINIMAL FLUNCTUATIONS
Constant
Temp:
6 AM - 38.3
10 AM - 38.5
2 PM - 39.0
Constant
6 AM - 40.3 ° C
10 AM - 38.0°
2 PM - 41.0 C
Remittent
On & Off Fever
INTERMITTENT & RELAPSING
Fever fever fever
REMIttent & Constant
Decline of Fever
LYSIS -
CRISIS/FLUSH -
“Sudden “ decline of fever
CRISIS / FLUSH
“Gradual” Decline
LYSIS
Clinical manifestations
Onset
EFFECTS OF FEVER
Good Effects
Bad Effects
- Enhanced cellular metabolism supporting MITOSIS
- Increased utilization of glucose by the cells making it less available for pathogens to consume.
- Mobilize and Activates WBC especially neutrophils
Good Effects of Fever
Cytoplasmic protein coagulation leadibg to “cell death” especially of the neurons.
Utilization of glucose and fat in recurring fever results in weight loss and fat loss
BAD EFFECTS OF FEVER