Fever - Naren Flashcards

1
Q

What is the most accurate place to measure temperature to estimate core temp?

A

esophagus, at the cardia.

This is not so easy to do, so rectal is the next best.

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2
Q

What is an exogenous factor? Endogenous?

A

something outside the body, like external temperature or humidity, physical activity, diet, or insulation.
Something inside the body, like progesterone, which increases temp; rhythms, gender, subcutaneous insulation

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3
Q

What is the best way to get rid of heat?

A

evaporation

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4
Q

Where is main control of temperature in the body located?

A

hypothalamus

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5
Q

Where are warm fibers located?

A

In Ruffini’s corpuscles.

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6
Q

Where are cold fibers located?

A

in the end-bulb of Krause

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7
Q

What channel do warm fibers use to send signals? What artificial substance is commonly used to activate it as a thermal pain therapy?

A

TRPV3. Capsaicin

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8
Q

Why does menthol generate a cold sensation?

A

It activates the cold fiber signal channels

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9
Q

What effect on temp will sympathetic nervous activation have?

A

Fight or Flight. It will cause increased metabolism, activity, and vasoconstriction to periphery so body temperature will rise

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10
Q

Would you expect hyper or hypothermia in a patient with severe goiter?

A

Goiter is a result of iodine deficiency. This will decrease thyroid function (hypothyroidism) and decrease metabolism and heat production, making the patient more susceptible to hypothermia

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11
Q

Which nervous system triggers sweat gland action?

A

sympathetic

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12
Q

What organ triggers signals to cause diaphoresis?

A

diaphoresis is sweating. Hypothalamus

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13
Q

What is CFDR?

A

a gene that controls ion channels across mucosa and glands. When defective, Cystic fibrosis.

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14
Q

Whose core temperature cools more slowly: men or women?

A

Women.
Though men have higher body temperature and are able to produce more heat; women core temperature stays warmer longer.
The extremities of women are in greater risk of cold damage though.

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15
Q

What evnironmental temperature would cause increase in epinephrine secretion?

A

cold.

epinephrine stimulates heat production.

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16
Q

What are the upper and lower temp limits for survival?

A

20-45 C, 74-114 F

17
Q

What is heat exhaustion?

A

the bodies respond to increased temp.
Vasodilation, sweating.
sweating can decrease ECF and blood volume, leading to hypotension and fainting.

18
Q

What is heat stroke?

A

body temp increases to point of damage. Usually happens because of impaired temp regulatory controls.

19
Q

What is malignant hyperthermia?

A

rare life threatening condition (usually hereditary) where a massive increase in metabolic rate and O2 consumption occur in response to inhalation anesthetics (halothanes)

20
Q

How can alcohol impair the bodies ability to react to extreme heat?

A

alcohol suppresses the sympathetic nervous system, impairing temperature regulation in either direction.

21
Q

What molecular signal resets hypothalamus temperature?

A

PGE2. This is upregulated by immune and inflammatory responses.