Fetus Varicella Syndrome

Question 1

Fetal Eyes in Varicella Syndrome

Answer 1

• Microphtalmia
• Chorioretinitis
• Cataracts

Question 2

Fetal Skin in Varicella syndrome

Answer 2

Scarring in dermatological distribution

Question 3

Fetal Limbs in varicella syndrome

Answer 3

Hypoplasia

Question 4

Neurological sequelae in fetus with varicella syndrome

Answer 4

• Microcephaly
• Cortical atrophy
• Mental restriction
• Dysfunction of bowel
• Dysfunction of bladder sphincters

Question 5

Facts about fetal varicella syndrome

Answer 5

• More likely if chicken pox in mother before 28 weeks, worse 3-28/40
• Result not from primary infection but reactivation in uterus
• Risk slightly lower in 1st trimester

Question 6

Amniocentesis in diagnosis of fetal varicella syndrome

Answer 6

• Strong negative predictive value but a poor positive predictive value in detecting fetal damage that cannot be detected by non-invasive methods
• It should not be performed before the skin lesions have healed

Question 7

USS in the diagnosis of fetal varicella syndrome

Answer 7

• At least 5/52 from initial exposure

- Fetal MRI could be considered