Fetus and the Newborn Flashcards
Risk Factors for Severe Bronchiolitis
FHx of Asthma School age kids at home No breast feeding Multiple Births Smokers Low Birthweight
Triple screen interpretation
AFP. HCG. E3
NTD. up. — —
Trisomy 21. Dn. up. Dn
Trisomy 18. Dn. Dn. Dn
Signs of Severe Brochiolitis
- O2 sat < 95%
- PO2 < 65%
- PCO2 > 40%
- CXR showing atelectasis
- RR> 70bpm
Lab/clinical Findings Consistent with CF
- FTT
- Decreased albumin
- anemia
- Hyponatremia
- recurrent pna
- steatorrhea
- Hypochloremic alkalosis
VOCAL CORD PARALYSIS
A baby with a hoarse cry
- difficulty on INSPIRATION
- normal puse ox with no response to Beta agonist
- blunted inpiratory loop on spirometry
- associated with Uri, Chemical exposure, GERD
When to Start Long acting Beta agonist on kids 0-4yrs
- at least 4 episodes of wheezing lasting longer than a day, that interferes with sleep and has a POSITIVE ASTHMA PREDICTIVE INDEX
- 2 or more exacerbation in the last 6 mo requiring oral CS
ASTHMA PREDICTIVE INDEX ( 1 major or 2 minor)
Major: MINOR
PARENTAL HX OF ASTHMA POS SKIN TEST
MD DX ATOPIC DERM EOSINOPHILIA > 4%
Wheezing without URI
Diagnosis of EXERCISE INDUCED ASTHMA
Consistent with a 15% decrease in PEFR or FEV1 during exercise challenge
RISK FACTORS FOR PERSISTENT ASTHMA
- Onset before age 3yr
- increased IgE
- Maternal HX of asthma
- eosinophilia
- Eczema or AR
- tobacco exposure
- obesity
ABPA
Colonization of the airways with hypersensitivity to mold
-TYPE I and TYPE III RXN
CLINICALLY
sputum eosinophilia
Increased serum IgE
Antibodies to A fumigates
RAST positive
BPD CLINICAL MANIFESTATION
Chronic Lung dz in infants
O2 Dependency beyond 28 DOL
CLINICAL Tachypnea SOB Tracheomalacia Cyonotic spells FTT Pulmonary HTN GERD Feeding problems
BETA 2 Adrenergic effects on NEONATES
Ex. Terbutaline (tocolytic)
Hyperinsulinism–» hypoglycemia
IVH GRADING
GRADE I – Germinal Matrix
GRADE II –IVH WITHOUT DILATATION
GRADE III – IVH WITH DILATATION
GRADE IV – EVERYTHING PLUS PARENCHYMAL INVOLVEMENT
Metabolic Derangements associated withIVH
Hyperglycemia
Thrombocytopenia
Hyponatremia
Acedemia
Occurs within 96 hrs of life
Metabolic Associations with Polycythemia
Hyperbilirubinemia
Thrombocytopenia
Hypoglycemia
Arterial blood gas values in normal NEONATES
PO2 60-90
PCO2 35-45
DISTINGUISHING RDS FROM GBS PNA IN A PREEMIE
Band:Neutrophil
If > or equal to 0.2 sepsis or PNA more likely
Breast Milk Content
GREATER IN
- protein
- Na
- lactoferrin
- LCFA
- IGA
Premature Breast Milk low in
- protein
- calcium
- VITAMIN D
- iron
- phosphate
Factors that reduce the incidence of Neonatal Jaundice
- maternal heroine
- smoking
- alcohol
- phenobarbital
- phenytoin
Estimate of Preemie BP
Mean arterial BP should not be < than corrected GA in weeks
Factors that impact the prognosis of preemies
GA
Morbidity in the NICU
INTRACRANIAL HEMORRHAGE
SE of MgSO4 on the NB
- delayed stooling
- thrombocytopenia
- neutropenia
Complications of Exchange Transfusion
Transfusion Impact No!!
Potassium high
Calcium low
Thrombocytopenia
Volume NO (hypovolemia)
Common Causes of Hemorrhagic dz of the NEW BORN
- maternal use of drugs
- anticonvulsants
- anticoagulants
- quinolones
- cephalosporins
- TB drugs
APT TEST
Tests for the presence of maternal blood in a neonates gastric aspirates