Fetal Growth Restriction Flashcards
Discuss the causes of a small fetus
Define the cocept of FGR
Pathophysiology of poor placentation using Doppler assessment
Methods of detecting FGR
Diagnotic and management differences
FGR
Notoriusly difficult to define
Definition is conceptual
Is a condition in which the fetus does not reach its biological growth potential
Often equated to being small
Not all small fetuses are growth restricted
Not all small fetuses are growth restricted
Not all growth restricted fetuses are small
Growth vs Size
Growth involves increment in a time interval
Usual method is to plot fetal size against gestationos
Causes of smallness
Dating problems
Constitutional
Primary fetal/ environmental problem
Placental insufficiency
Smallness: Fetal/Environmental
ROCK BOTTOM FEET
Inefection (HPV) causing deformities
Smallness: Fetal/Environmental
Chromosomal conditions
Congenital infections
Genetic syndromes
Teratogens
Maternal problem (Cyano
Placental insufficiency
Placenta function is nutrient and gas exchange
Poor function will lead:
- slowing growth
- hypoxemia-> hypoxia–> asyphyxia
Placentall insufficency: clinical setting
Risk factor
- maternal age >40years
- ongoing smoker (at booking)
- drug misuse
previous history
positive uterine artery doppler screen
abnormal placental echo-texture
AC/EFW below the 3rd centile
SMOKING: lesser chance of eclampsia
Foetal-maternal circulation
Umbilical arteries have deoxygenated blood and travel to placenta
Umbilical vein has oxygenated blood
Ductus venosus shunts the blood through the foramen ovale straight into the left side of the heart and then systemic circulation- first goes to head + neck via carotid, so goes up to brain
Then goes back down descending aorta and back to placental arteries
Doppler looks at placental function + foetal response
Test placental function on maternal and foetal side
Maternal = uterine arteries
Foetal = umbilical arteries- want a low resistance for good perfusion
Consider foetal response too:
Foetal = middle cerebral artery (want high resistance as low resistance means there’s a lack of oxygen), ductus venosus (backflow means there’s no perfusion)
Important things to consider;
Uterines- maternal side of placental function
Umbilical arteries- foetal side of placental function
Foetal response to any hypoxia
Middle cerebral artery- is it compensating?
Is baby decompensating w abnormal ductus venosus?
Redistribution
In case of baby having hypoxia, there will be shunt to the brain (can be detected)
(PLACENTAL FUNCTION- LOOK AT BABy’S RESPONSE TO IT)
Uterine arteries is maternal
Umbilical arteries is foetal
High resistance in in the heart= high resistance in the uterine areries