FETAL DEVELOPMENT Flashcards
When do centers of ossification appear?
12 wks
When do skin and nails develop?
12 weeks
When are fingers and toes differentiated?
12 weeks
When do eye movements begin?
16 weeks
When does midbrain maturation begin?
16 weeks
When do eyes open?
26 weeks
When does subcutaneous fat deposit?
36 weeks
When does vernix caseosa form over skin?.
28 weeks
When does vaginal canalization begin?
16 weeks
When does testes descend?
20 weeks
When does canalicular development complete?
24 weeks
When is the fetal liver and spleen the sites of hematopoiesis
28 weeks
When does type ii pneumocytes begin to secrete surfactant?
24 weeks
When does downy lanugo cover the body?
20 weeks
When does fetal uterus form?
16 weeks
When do fingers and toes differentiate?
12 weeks
When is the bone marrow the major site of hematopoeisis?
28 weeks
What significant fetal changes occur during 36 weeks?
Subcutaneous fat deposition
Body becomes rotund
Face becomes fuller
What significant fetal changes occur during 28 weeks?
Vernix caseosa
Bone marrow for hematopoiesis
What significant fetal changes occur during 24 weeks?
Skin wrinkles, fat deposits begin
Head enlarged
Canaliculra kung devt nearly complete
Surfactant begins
When does brown fat form?
20 weeks
What significant fetal changes occur during 20 weeks?
Testes descends
Brown fat forms
Downy lanugo
What significant fetal changes occur during 16 weeks?
Eye movement
Midbrain maturation
Uterus
Vaginal canalization
What significant fetal changes occur during 12 weeks?
Centers of ossification
Skin and nails
Fingers and toes
What significant fetal changes occur during 4-5 weeks?
Ureteric bud from mesonephric duct will become the kidney
What significant fetal changes occur during 7 weeks?
Cloaca divides into rectum and urogenital sinus
What are the three parts of the urogenital sinus
Cephalad (vesicle): bladder
Middle (pelvic): urethra
Caudal (phallic): lower vagina, batholins and paraurethral glands
What significant fetal sex changes occur during 10th week?
Uterus is formed by union of mullerian ducts in the middle
What significant fetal sex changes occur during 16th week?
Primordial follicle begin to form which contain oogonia
What significant fetal sex changes occur during 20th week?
Final uterine cavity formed
Vaginal canalization is complete (begins at 16 weeks)
Three fetal shunts
Ductus venosus
Foramen ovale
Ductus arteriosus
What are the 3 umbilical vessels
AVA
2 arteries
1 vein
Trace flow of blood from placenta
Oxygenated - Umbilical vein - Portal v (liver) - Ductus vein (IVC) Mixed blood - IVC - Right atrium - foramen ovale - left atrium - left ventricle - aorta - common iliac (2) - hypogastric a (2) - umbilical a (2)
Functional closure
Ductus arteriosus
10-12 hours
Functional closure
Foramen ovale
Few mins
Functional closure
Ligamentum venosum
10-96hours
Closure
Ligamentum teres
3-4 days
Closure of umbilical ligament
3-4 days
Anatomic closure
Ductus arteriosis
2-3 weeks
Anatomic closure
Foramen ovale
1 yr
Anatomic closure
Ligamentum venosum
2-3 weeks
Fetal lung development Pseudoglandular stage (1st): growth of intrasegmental bronchial tree
5-17 weeks
When can chest wall movements be detected sonographically?
11 weeks
Fetal lung development
Canicular lung development is nearly complete by
24 weeks
Type II pneumocytes begin to secrete surfactant by
24 weeks
Terminal sac stage (3rd) by?
25 weeks
Which stage of fetal lung development involves growth of intrasegmental bronchial tree?
A. 1st - Pseudoglandular stage
B. 2nd - canalicular stage
C. 3rd - terminal sac stage
A. Pseudoglandular stage (1) at 5-17 weeks