Fertility Flashcards

1
Q

Which cell type secretes mullerian hormone

A

Granulosa cells

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2
Q

When is mullerian hormone produced

A

From 36 weeks gestation till menopause

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3
Q

What is the predominant cause of anovulatory infertility

A

PCOS

>80-90% of cases

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4
Q

What is the main mechanism by which hyperprolactinaemia causes secondary amenorrhoea

A

Inhibition of LH pulsatility

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5
Q

What classification of OHSS is described below

Abdominal bloating
Mild abdominal pain
Ovarian size usually 8cm

A

Mild OHSS

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6
Q

What classification of OHSS is described below

Moderate abdominal pain
N&V
USS ascites
Ovarian size 8-12cm

A

Moderate OHSS

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7
Q

What classification of OHSS is described below

Clinical ascites 
Oliguria
Haematocrit >45%
Hypoproteinaemia
Ovarian size usually >12cm
A

Severe OHSS

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8
Q

What classification of OHSS is described below

Tense ascites or large hydrothorax
Haematocrit >55%
Wcc >25,000/ml
Oligo/anuria
Thromboembolism 
Acute respiratory distress syndrome
A

Severe OHSS

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9
Q

How is the free androgen index calculated and when is it used

A

Baseline chemical test for hyperandrogenism

Total testosterone divided by sex hormone biding globulin x 100

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10
Q

What proportion of PCOS are overweight or obese

A

40-50%

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11
Q

What is the estimated level of endometriosis in infertile women

A

50%

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12
Q

How long after rubella vaccine should women wait prior to attempting conception

A

1 month

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13
Q

What is the minimum endometrial thickness advised prior embryo transfer

A

5mm

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14
Q

Regarding semen WHO normal ranges, what is the

Semen volume

A

1.5ml

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15
Q

Regarding semen WHO normal ranges, what is the

sperm concentration

A

15 10*6ml

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16
Q

Regarding semen WHO normal ranges, what is the

Total number

A

39 10*6/ejaculate

17
Q

Regarding semen WHO normal ranges, what is the

Total motility

A

40%

18
Q

Normal adult range for male FSH

A

1.5-12.5

19
Q

What are the markers of a high responder for IVF

A

Antral follicle count >16
Mullerian hormone >25
FSH <4

20
Q

What are the markers of a low responder for IVF

A

Antral follicle count <4
Mullerian hormone <5
FSH > 9

21
Q

Regarding semen WHO normal ranges, what is the

Progressive motility

A

32%

22
Q

Regarding semen WHO normal ranges, what is the

pH

A

> 7.2

23
Q

Regarding semen WHO normal ranges, what is the

Total vitality

A

58%

24
Q

Regarding semen WHO normal ranges, what is the

Normal forms

A

4%