Fertility Flashcards
Which cell type secretes mullerian hormone
Granulosa cells
When is mullerian hormone produced
From 36 weeks gestation till menopause
What is the predominant cause of anovulatory infertility
PCOS
>80-90% of cases
What is the main mechanism by which hyperprolactinaemia causes secondary amenorrhoea
Inhibition of LH pulsatility
What classification of OHSS is described below
Abdominal bloating
Mild abdominal pain
Ovarian size usually 8cm
Mild OHSS
What classification of OHSS is described below
Moderate abdominal pain
N&V
USS ascites
Ovarian size 8-12cm
Moderate OHSS
What classification of OHSS is described below
Clinical ascites Oliguria Haematocrit >45% Hypoproteinaemia Ovarian size usually >12cm
Severe OHSS
What classification of OHSS is described below
Tense ascites or large hydrothorax Haematocrit >55% Wcc >25,000/ml Oligo/anuria Thromboembolism Acute respiratory distress syndrome
Severe OHSS
How is the free androgen index calculated and when is it used
Baseline chemical test for hyperandrogenism
Total testosterone divided by sex hormone biding globulin x 100
What proportion of PCOS are overweight or obese
40-50%
What is the estimated level of endometriosis in infertile women
50%
How long after rubella vaccine should women wait prior to attempting conception
1 month
What is the minimum endometrial thickness advised prior embryo transfer
5mm
Regarding semen WHO normal ranges, what is the
Semen volume
1.5ml
Regarding semen WHO normal ranges, what is the
sperm concentration
15 10*6ml