Fertilisation Flashcards
What are the pre fertilisation events of sperm
Traverse vagina
Transverse cervix
Movement to oviduct
Storage in oviduct
Further maturation “capacitation”
What might stop sperm from traversing at the vagina and how do they counteract this
Low pH in vagina
Prostate gland secrete alkaline solution to protect from acidity
Where is the prostate gland situated
In true pelvis
What might stop traversing of sperm in the cervix
Mucus present - traps sperm
Antibodies present to agglutinate sperm
Phagocytes present
What might stop sperm at the oviduct
Immunological defences of female
What happen to sperm at the oviduct in terms of storage
Acrosome binds to to receptor on mucosa - sperm reservoir waiting for ovulation
Where does the sperm stop moving at the oviduct
Isthmus
What does capacitation mean
Any change of the acrosome for acrosomal reaction
What doe hyperactivation mean
Changes in flagella beating
What happens at the further maturation stage of pre fertilisation of sperm
Sperm let go of isthmus and move to ampulla - final maturation
What does oestrogen do in terms of ovulation
stimulates release of LH
What does LH in terms of ovulation
Induce ovulation
Causes follicles to have growth spurt
What happens during ovulation
Oocyte detaches from follicle
Fimbrae of oviduct reposition to catch oocyte from ovary
Oocyte transported to oviduct
What does sperm push through and bind to during acrosome reaction
Push through follicular cells of corona radiata
Binds to zona pellucida
What is cortical reaction
Release of enzymes that prevent further binding of sperm to egg
